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7 Cards in this Set

  • Front
  • Back
Draw a sarcomere. What fibres make up which part of it?
Actin = thin filaments
Myosin = thick filaments (M band)
Absolute vs relative refractory period
• Absolute refractory period
• Time period when no action potential can be generated.
• Due to the fact that..
□ Some Na+ channels are still inactivated
□ Some K+ channels are still open, and thus the membrane potential is still hyperpolarized (further away from threshold).

• Relative refractory period
• Generates an AP.
• Requires greater stimulus intensity than usual.
States of voltage-gated channels through the phases of an action potential.
A. Resting state
B. Rising phase
C. Falling phase
D. Afterhyperpolarization
What is the neurotransmitter for excitation at the spinal cord between a sensory Ia afferent neuron, and an alpha motor neuron? What is the neurotransmitter receptor called?
Neurotransmitter = glutamate
Receptor = AMPA receptor, which is also a non-specific cation channel.
What is the distance that a neuronal membrane depolarization can travel determined by?
The distance a depolarization can propagate along a neuron is governed by two factors:
• Axial resistance (Ra)
□ Increasing the diameter of the axon = decrease in Ra

• Membrane resistance (Rm).
□ Rm is increased by myelination
Length constant = (Rm/Ra) ^ 1/2
-An increase in Rm, or decrease in Ra, results in longer propagation distance
What factors affect the rate, or speed of the action potential propagation?
1. Diameter of the neuron.
- the larger the faster.
2. Membrane capacitance.
- lower capacitance = less time to charge the membrane, and greater rate of AP propagation.
- capacitance is inversely proportional to the distance between the parallel plates. Myelin increases the thickness of the membrane.
- capacitance is also proportional to the surface area of the membrane.
Sequence of events between myosin and actin filament during a contraction-relaxation cycle