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15 Cards in this Set

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  • Back
What is the difference in the complete lipoprotein panel and a secondary lipoprotein panel?
Complete lipoprotein profile is preferred. It includes
fasting total cholesterol, LDL, HDL, triglycerides.

The secondary option is non-fasting and includes total cholesterol and HDL.
What do test do you order if the secondary lipid panel (non-fasting) comes back with TC>200 mg/dL or HDL <40 mg/dL?
Proceed to full lipoprotein profile.
What are the 5 major risk factors for determining 10 year CHD risk and LDL goals?
-Cigarette Smoking
-HTN: (BP ≥140/90 mmHg or on antihypertensive medication)
-Low HDL: (<40 mg/dl)
-Family history of premature CHD: (CHD in male first degree relative <55 years; CHD in female first degree relative <65 years)
-Age: (Men ≥45 years; women ≥55 years)
The following account for what in relation to hyperlipidemia:

Genetic Factors
Acquired Defects
Aging
Weight Gain
Poor Diet
Sedentary Lifestyle
Causes of primary hyperlipidemia.
What are the causes of secondary dislipidemia?
*Diabetes- the BIG ONE!
*Hypothyroidism- T4 is responsible for regulating metabolism. In this condition you put on the weight.
*Obstructive liver disease-if obstruction can’t breakdown lipids
*Chronic renal failure- if you are losing proteins in urine, liver starts kicking out more protein.
*Drugs that raise LDL cholesterol and lower HDL cholesterol (progestins, anabolic steroids, and corticosteroids)
What is the LDL goal for:
A. CHD Risk equivalent

B. 2+ risk factors

C. 0-1 risk factor
A. CHD Risk Equivalent:<100

B. 2+ Risk factors: <130

C. 0-1 Risk factors: <160
What is the 10 year risk of developing CHD if a patient has:
A. CHD Risk equivalent

B. 2+ risk factors

C. 0-1 risk factor
A. CHD Risk equivalent: >20%

B. 2+ risk factors: 10-20%

C. 0-1 risk factor: <10%
What is the standard 1st visit concerning lipid management?
*Begin Therapeutic Lifestyle Changes

*Emphasize reduction in saturated fats and cholesterol

*Initiate moderate physical activity

*Consider referral to a dietitian (medical nutrition therapy)

*Return visit in about 6 weeks
What is the standard 2nd visit concerning lipid management?
Evaluate LDL response

Intensify LDL-lowering therapy (if goal not achieved)
*Reinforce reduction in saturated fat and cholesterol
*Consider plant stanols/sterols
*Increase viscous (soluble) fiber

Consider referral for medical nutrition therapy

Return visit in about 6 weeks
What is the standard 3rd visit concerning lipid management?
Evaluate LDL response

Continue lifestyle therapy (if LDL goal is achieved)

Consider LDL-lowering drug (if LDL goal not achieved)

Initiate management of metabolic syndrome (if necessary)

Intensify weight management and physical activity

Consider referral to a dietitian
At what stage in hyperlipidemia DRUG THERAPY do you refer out to a specialist?
3rd
How long before you try drug therapy in a patient with hyperlidemia?
After about 3 months of TLC
When drug therapy is initiated for hyperlipidemia, what are the usual drug choices?
Initiate LDL-lowering drug therapy

*Usual drug options
Statins
Bile acid sequestrant or nicotinic acid

Continue therapeutic lifestyle changes

Return visit in about 6 weeks
What age group do men have a greater CHD risk than women?
Middle age 35-65.
At what age do women tend to develop CHD?
Most CHD in women occurs after age 65

CHD in women delayed by 10–15 years (compared to men)