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48 Cards in this Set
- Front
- Back
SIGECAPS
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Sleep
interest guilt energy concentration appetitie psychomotor suicidality |
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melancholia criteria
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anhedonia plus three of:
diurnal variation pervasive adn irremediable depressed mood marked psychomotor retard or agitation sig weight loss or anorexia excessive or inappropriate guilt early morning awakening |
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what type of depression responds best to phramacotherapy
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melancholia
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what depressed patients have high risk for suicide
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with psychotic features such as hallucinations and delusions
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criteria for atypical depression
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mood reactivity plus two of
- leaden paralysis - hypersomnia - rejection hypersensitivity - overeating - weight gain |
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major complaint in major depression
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anhedonia, NOT depressed mood
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what's depressed mood or anhedionia for less than two weeks, not due to a stressor? due to a stressor?
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depressive d/o NOS (or nothing)
vs adj d/o with depressed mood |
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cancers associated with depression
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brain
pancreatic |
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type of thyroid disease associated with depression
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hyper and hypo
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IDs associated with depression
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HIV
syphilis hepatitis lyme |
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what is dysthymic d/o
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chronic form of depression with 2 years of symptoms on more than half the days
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which responds better to drugs, depression or dysthymia
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depression
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time criteria for dysthymic d/o
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2 years (1 for adol and kids)
never without symptoms for more than 2 months at a time no MD during first two years |
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symptom criteria for dysthymic
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poor appetitie or overeating
insomnia or hyper low energy or fatigue low self-esteem poor concentration or difficulty decidin feelings of hopelessness |
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at what time point in bereavement do you consider MD as a diagnosis
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> 2 mos
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time criteria for adj disorder
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within 3 months of identifiable stressor
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treatment for adj d/o
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psychotherapy not drugs
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effect of SSRIs in pregnant women
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small risk in newborn of a transient withdrawal syndrome
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drugs of choice for pregnant depressed women
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SSRIs but NOT paroxetine
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which patients have a high risk of having recurring chronic depression
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people who are elderly when their first episode is diagnosed
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elderly person with insomnia, anorexia and fatigue
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depression
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drug for elderly depressed person
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SSRI
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tx for pseudodementia
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drugs
ECT |
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most specific symptom for bipolar disorder
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hypomanic episode
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criteria for manic episode
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1 week (or anything if need hospitalization)
3 or more of these during mood disturbance (4 if only irritable): - grandiosity - decreased sleep - talkative - flight of ideas, racing thoughts - distractibility - increased goal directed - excessive pleasurable activity not a mixed episode marked impairment not from substance |
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criteria for hypomanic
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at least 4 days
3 or more, 4 if irritable, of: - grandiosity - less sleep - talkative - FOI - distractibility - goal directed - pleasurable activities unequivocal change in function mood/function change observable not casing impairment not due to substance |
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which is more lethal in suicide attempts, SSRI or TCA
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TCA
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goal of acute phase tx for depression
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remission for a minimum of 6-8 weeks
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what absolutely must be present in acute phrase t
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psychiatric management
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how to differentiate non-, partial response, partial remission
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less than 25% decrease in baseline sx
vs 26-49% decrease vs 50% or greater ecrease with residual |
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what is first response if patients don't fully respond in acute phase
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increase dose
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when do you start reviewing causes of lack of moderate improvement in depression symtoms
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after initial 4-8 weeks
(first increase dose, then consider other things) |
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how long is the continuation phase
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16-20 weeks
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minimum length of tx for depression
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remission plus 16-20 weeks of continuation therapy
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what's purpose of maintenance phase tx for depression
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preventing recurrence
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dosing in maintenance phase
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same as in acute and continuation
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phases of medication
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Acute
Continuation Maintenance |
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which antidepressants are best for MD
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they're all good
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what are TCAs better for
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severe depression
depression with melancholia depression with physical pain |
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what shouldn't be given to heart patients
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TCAs
NRI |
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contraindications for TCAs and NRIs
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CV (esp conduction)
BPH urinary retention closed angle glaucoma |
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what are venlafaxine, milnacipran, duloxetine
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SNRIs
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antidepressants for chronic pain and diabetic neuropathy
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duloxetine
paroxetine |
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what does bupropion inhibit
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norepi
dopamine (not serotonin) |
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what are MAOIs better at
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atypical depression
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what does nefazodone block
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5-HT serotonin receptors
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what does mirtazapine block
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alpha 2 adrenergic receptors
specific serotnin receptors histamine receptors |
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on PHQ 9 what is scale
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0-4 non
-9 mild -14 moderate -19 moderately severe -27 severe |