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13 Cards in this Set
- Front
- Back
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Isoproterenol Dose Range and Effect
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2-30 mcg/min
Selective Beta1 and 2 Agonist |
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Milrinone Dose Range and Effect
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0.25-1.0mcg/kg/min
Phosphodiesterase Inhibitor (Incr. C-AMP lvls) |
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Dobutamine Dose Range and Effect
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2.5-20mcg/kg/min
Selective Beta1 Receptor Stimulant Little Alpha1 (vasoconstrictive) Effect |
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Dopamine Dose Range and Receptor/Effect
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Low Dose: 3-5mcg/kg/min
-Dopamine Receptors in Renal and Mesenteric Arteries = Vasodilation and Increased Perfusion Moderate Dose: 5-10mcg/kg/min Primary Beta1 Cardiac Receptors = Inotropic and Chronotropic Effects -High Dose: 10-20mcg/kg/min Primary Alpha1 Receptors = Peripheral Vasoconstriction |
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Epinephrine Dose Range and Effect
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1-5 mcg/min
Alpha, Beta 1 and 2 Agonist |
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Norepinephrine/Levarterenol
(Levophed) Dose Range and Receptors |
Alpha and Beta Agonist
2-12 mcg/min |
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Phenylephrine (Neo-Synephrine)
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Selective Alpha Agonist
100-200mcg/min |
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Dobutamine (Dobutrex)
Effects |
SELECTIVE BETA1 AGONIST
-Incr. Contractility and SV -Minimal Incr. HR -Decr. LV filling Pressure/PVR -Incr. O2 consumption -Incr. AV node conduction (arrhythmogenic potential) |
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Dopamine-Dobutamine Concentrations Rationale
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Dopamine 1.0-5.0 mcg/kg/min (Renal Perfusion)
Dobutamine 2.5 - 10 mcg/kg/min (Inotropic Effect) |
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Dopamine and Dobutamine Adverse Effects
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Tachyphylaxis (particularly if used > 72 hrs)
-Tissue Hypoxia -Met Acidosis -ARF -Infiltration Ectopy -V Tach -Incr Myocardial O2 consumption |
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Epinephrine mechanism of Action
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ALPHA, Beta 1 and 2 Agonist
Relaxation of bronchial smooth muscle Incr Cardiac Output Incr Myocardial Irritability and Incr Coronary Blood FLow Peripheral Vasoconstriction with Decr. Renal Blood Flow |
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Isoproteronol Effects
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-Relaxation of bronchial smooth muscle
-Incr. myocaridal contractility, HR, and O2 consumption -Coronary artery Dilatiation -->Coronary steal + worsening ischemia -Peripheral Vasodilation with AV shunting -Arrhythmogenic potential (V tach) |
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Levophed Effects
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ALPHA AND BETA AGONIST
Incr. PVR w/ increased SBP/DBP Reduced blood flow to peripheral tissues/organs Pulmonary Vasoconstriction Principal Cardiac Effect: Positive Inotropic Effect with Incr. O2 Consumption |
