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15 Cards in this Set
- Front
- Back
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What is Nitrates is the primary use of nitrates and side effects |
Primary use: angina
Side effects: dizziness, headache,tachycardia |
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What is Calcium Channel Blockers primary use and side effects |
Primary use: Angina,hypertension, supraventricular arrhythmias
Side effect: dizziness, headache, cardiac depression
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What is its mechanism of action |
Blocks the influx of extra-cellular calcium into cardiac and vascular smooth muscle resulting in reduced contractility, slows conduction through AV node (especially verapamil), peripheral vasodilation, dilate coronary arteries |
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What are the primary and side effects of beta blockers |
Primary use:angina, arrhythmias, hypertension. Also effective in slowing progression of CHF by blocking sympathetic nervous system
Side effects: Bronchospasm (not recommended for asthmatics), AV block, lower HDL and higher TG, masks symptoms of hypoglycemia (not recommended for diabetics), abrupt withdrawal can cause angina and MI |
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What are the different types |
1) Non-selective inhibit both beta-one (heart) and beta-two (peripheral arteries) receptors 2) Selective inhibit only beta-one receptors |
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What are the mechanism of action |
Reduce heart rate and contractility (both types), slow heart rate results in increased diastolic filling time which allows more oxygen-rich blood to perfuse the myocardium, blocking of sympathetic input reduces likelihood of arrhythmias. |
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What are the primary use and side effects in alpha 1 antagonist |
Primary use: Hypertension
Side effect:: Orthostatic hypotension, lower LDL and higher HDL, better for asthmatics than B-blockers, improves urinary function especially in men with prostatic hyperplasia (enlarged prostate) |
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What are the mechanism of action |
induce vasodilation by blocking Alpha I receptors (key regulator of vascular smooth muscle tone) |
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What are the primary uses of ACE Inhibitor |
-hypertension - Inhibits conversion of angiotensin I to angiotensin II via angitensin converting enzyme- Fewer side effects but can produce cough in some people-Improve vasomotor function – reduced levels of Ang II and aldosterone reduces ROS and increases NO -May reduce morbidity and mortality in CHF, stroke, and renal disease
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What are Angiotensin II primary use |
: hypertension,Blocks Ang II from binding to its receptors,Similar mechanism of action and benefits as ACE inhibitors with fewer reports of coughing,Angiotensin II is vasotoxic
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What are Aldosterone receptor blocker |
hypertension,Blocks Ang II from binding to its receptors,Similar mechanism of action and benefits as ACE inhibitors with fewer reports of coughing,Angiotensin II is vasotoxic
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what are the primary use for Digitalis |
Increases myocardial contractility and reduces supraventricular arrhythmias (i.e., atrial flutter or fibrillation),Reduces conduction velocity through AV node,Correct dosage sometimes difficult to determine
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What are the primary uses of Anti coagulants? |
anti-thromoblytic,Traditional meds such as heparin and warfarin (Coumadin) as well as newer rivaroxaban (Xarelto) block the blood clotting pathway at different points.Clopidogrel (Plavix) and aspirin act directly on the platelets, inhibiting aggregation. Aspirin is also anti-inflammatory.
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what is Aspirin |
Ø anti-inflammatory
Ø anti-coagulant |
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What is primary use of Statin |
blood cholesterol levels Not only improve blood cholesterol profile but also
Ø reduce intraplaque lipids Ø stabilize atherosclerotic plaque Ø improve vasomotor function (reduce ROS)
Ø anti-inflammatory |
