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10 Cards in this Set
- Front
- Back
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What is normal COHb?
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1%
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What is a smoker's COHb?
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3-15%
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What is the effect of increased COHb on the O2 dissociation curve?
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Shifts left d/t decreased O2 release to tissues
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What is the effect of inactivity (anesthesia, sleep) on COHb?
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Doubles
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What is the t1/2 of nicotine after 1 cigarette?
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30 minutes
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What are the effects of nicotine on the ANS?
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Increase Epi, Norepi, GF corticol
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What are the effects of nicotine on P450?
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Decreased intensity/duration of drugs metabolized in liver 10-15%
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What are the CV effects of smoking?
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CAD, PVD, stroke
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What are the respiratory effects of smoking
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COPD, reduced lung fx
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What are the GI effects of smoking?
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PUD, GERD, gum ds, tooth loss
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