Practice4 Test 1 Set 1

Front 1

Drug History on Rx meds should include....(5)

Back 1

1)dose/frequency
2)time of admin
3)indication
4)duration of therapy
5)pharmacy/ies

Front 2

Drug History on NonRx meds should include... (7)

Back 2

1)HEENT (drops, sprays, analgesics)
2)respiratory (antihistamines, decongestants, cough/cold)
3)GI (constipation, diarrhea)
4)System wide (vitamins, herbals)
5)smoking/alcohol use
6)special diet restrictions
7)allergy hx and details

Front 3

Statin class CI's (3)

Back 3

1)liver disease
2)LFT elevations
3)pregnancy

Front 4

Statin class precautions (3)

Back 4

1)alcoholism
2)myopathy
3)rhabdomyolysis w/ renal failure

Front 5

Statin class drug interactions (1)

Back 5

1)myopathy w/ co-admin of fibrates, niacin, erythromycin

Front 6

Statin class ADR's (2)

Back 6

1)GI
2)HA

Front 7

Statin class pt consultation (2)

Back 7

1)LFT monitoring
2)watch out for muscles aches (myopathies)

Front 8

Lipid disorder classes (6)

Back 8

I)chylomicrons
IIa)LDL
IIb)LDL/VLDL
III)IDL
IV)VLDL
V)VLDL and chylomicrons

Front 9

Crestor
a)FDA indications
b)Drug interactions (3)
c)Pt consultation

Back 9

a)2a/b, 4 lipid disorder
b1)incr warfarin levels
b2)lopid incr crestor levels
b3)antacids limit crestor absorption
c)do not take antacids within 2hrs b4 or after

Front 10

Lescol
a)dosage forms
b)FDA indications

Back 10

a)IR and XL
b)2a/b ONLY

Front 11

Lipitor
a)FDA indications
c)drug interactions (3)
d)Pt consultation

Back 11

a)2a/b, 4
c1)incr digoxin levels
c2)AZOLE antifungals incr lipitor levels
c3)grapefruit juice incr lipitor levels
d)avoid grapefruit juice

Front 12

AZOLE's....

Back 12

are strong 3A4 inhibitors

Front 13

Lovastatin
a)FDA indications
c)CI*****
d)drug interactions (2)
e)pt consultation (2)

Back 13

a)2a/b
c)sporanox (itraconazole)
d1)AZOLE antifungals incr lovastatin levels
d2)grapefruit juice incr lovastatin levels
e1)avoid grapefruit juice
e2)admin w/ EVENING MEAL for max absorption

Front 14

Pravachol
a)FDA indications
b)drug interactions
c)pt consultation (2)

Back 14

a)2a/b
b)BAS limit absorption
c1)give 1hr b4 or 4hrs after BAS
c2)bedtime dosing

Front 15

Zocor
a)FDA indications
b)CI
c)pt consultation (2)

Back 15

a)2a/b, 4
b)sporanox (itraconazole)
c1)avoid grapefruit juice
c2)evening dosing

Front 16

Zocor drug interactions (5)

Back 16

1)incr digoxin/warfarin levels

ALL THE FOLLOWING INCR ZOCOR LEVELS
1)cyclosporine
2)amiodarone
3)verapamil
4)AZOLE antifungals

Front 17

Statins metabolized by CYP3A4 (3)

Back 17

1)zocor
2)lipitor
3)lovastatin

Front 18

Gemfibrozil
a)FDA indications
b)dose when
c)drug interactions (2)
d)CI (2)
e)pt consult

Back 18

a)4; low HDL/high LDL
b)30min prior to am/pm meal
c1)incr warfarin levels
c2)statins (risk of myopathies)
d1)hepatic/renal dysfxn
d2)gallbladder disease
e)watch for myopathies

Front 19

Tricor
a)FDA indications
b)dose when
c)drug interaxns (2)
d)CI (3)
e)ADR
f)pt consultation

Back 19

a)2a/b; 4
b)w/ meals
c)warfarin/statins (like lopid)
d1)liver/renal dysfxn
d2)gallbaldder disease
d3)LFT elevations
e)LFT elevations
f)surveillance for myopathy

Front 20

Fibrates incr chance of...

Back 20

GALL STONES

Front 21

Questran (cholestyramine)
a)drug interactions
b)precautions
c)ADR (3)
d)pt consultation (3)
e)can treat...

Back 21

a)reduce absorption of many drugs
b)GI motility problems
c1)CONSTIPATION
c2)n/v
c3)can raise TG
d1)give other meds 1hr before or 4hr after this one
d2)give w/ lotsa fluids
d3)counsel on mix instructions and potential for constipation
e)11-20yo

Front 22

Welchol (cholesevelam)
a)dosing
b)precautions
c)ADR (2)
d)pt consult

Back 22

a)3tabs bid or 6tab qd @ one meal
b)GI motility problems
c1)constipation
c2)dyspepsia
d)take w/ lotsa fluids

Front 23

Niaspan
a)FDA indications
b)dose when
c)drug interaxn
d)CI (3)
e)monitor what...
f)ADR (3)
e)pt consult (2)

Back 23

a)2a/b; 4
b)bedtime w/ snack
c)statins (may incr myopathies)
d1)hepatic dysfxn/LFT elevations
d2)gout
d3)DM
e)base and follow-up LFT's
f)flushing, GI, rash
e1)premedicate w/ ASA/NSAID for flushing
e2)avoid alcohol

Front 24

Zetia
a)FDA indications
b)drug interactions (2)
c)precautions
d)pt consult (3)

Back 24

a)LDL reduction
b1)fibrate incr Zetia[]
b2)questran decr Zetia[]
c)hepatic dysfxn
d1)w/o regard to meals
d2)do NOT take within 2hrs before or 4hr after a BAS
d3)myopathy risk if taking w/ statin

Front 25

Vytorin is...

Back 25

zocor and zetia

Front 26

Diuretic
a)class CI (2)

Back 26

1)anuria
2)electrolyte depletion

Front 27

Diuretic class precautions (3)

Back 27

1)monitor electrolyte losses (b/c these can exacerbate arrhythmias and A.Fib)
2)DM (b/c if hypokalemia occurs, this can cause hyperglycemia)
3)gout

Front 28

Diuretic class drug interactions (3)

Back 28

1)digoxin (K+ loss can cause digoxin toxicity)
2)NSAID (negate some Na loss = decr diuretic fxn)
3)Lithium

Front 29

Diuretics class ADR's (6)

Back 29

1)decr K/Mg/Ca
2)hyperglycemia
3)incr uric acid/BUN
4)photosensitivity
5)dry mouth/dizziness
6)weakness/cramps

Front 30

Diuretic pt consultation (2)

Back 30

1)give in am w/ food/milk
2)avoid OTC laxatives (incr K/Mg loss)

Front 31

Loop diuretics general monitoring and 3ex of loops

Back 31

excrete more K/Mg/Ca than other diuretics

1)furosemide
2)torsemide
3)bumetanide

Front 32

Thiazide diuretics general monitoring and 3ex of loops

Back 32

primarily excretes K

1)HCTZ
2)indapamide
3)metolazone

Front 33

Loop + thiazide =

Back 33

major electrolyte loss

Front 34

Thiazide + K-sparing diuretic =

Back 34

K+ neutral

Front 35

Furosemide
a)dosage forms (3)
b)PK (3)

Back 35

a)tablets, solution, IV
b1)diuresis onset 30-60min
b2)F=50-60%
b3)oral dose is 2x the IV dose

Front 36

Bumetanide (Bumex)
a)dosage forms (2)
b)PK (2)

Back 36

a)oral, IV
b1)diuresis onset 30-60min
b2)F=80-90% (no adjustment oral to IV)

Front 37

Demadex
a)dosage forms (2)

Back 37

tablet, IV

Front 38

HCTZ
a)dosage forms
b)precautions

Back 38

a)tablets
b)less effective in pts w/ bad renal fxn

Front 39

Indapamide (lozol)
a)dosage forms

Back 39

tablets

Front 40

Zaroxolyn (metolazone)
a)dosage forms
b)use
c)precautions

Back 40

a)tablets
b)used in combo w/ loops for enhanced diuresis
c)close F&E monitoring needed

Front 41

Sprionolactone
a)FDA indications (2)
b)drug interactions (2)
c)CI (3)
d)ADR (2)

Back 41

a1)HTN
a2)edema due to CHF, nephrotic syndrome or cirrhosis
b1)ACEI
b2)K+ sparing meds/supplements
c1)anuria
c2)renal insufficiency
c3)hyperkalemia
d)HYPERKALEMIA, man boobs

Front 42

Dyazide/Maxzide
a)dosage forms and strengths
b)FDA indications (2)
c)precautions

Back 42

a)dyazide-capsules (37.5/25)
maxzide-tablets (37.5/25 & 75/50)
b1)HTN
b2)edema
c)when using other K+ sparing agents

Front 43

Potassium
a)ADR (3)
b)Pt consultation (2)

Back 43

a)diarrhea, n/v, ab cramps
b1)take w/ meals AND full glass of water
b2)swallow all but K-Dur whole (it can be divided)

Front 44

BB class CI (3)

Back 44

1)cardiogenic shock
2)bradycardia
3)no BB in decompensated CHF

Front 45

BB class precautions (2)

Back 45

1)asthma
2)DM

Front 46

BB class drug interactions (3)

Back 46

1)verapamil (additive bradycardia)
2)clonidine
3)NSAIDs (decr BB effect on BP)

Front 47

BB class ADR's (4)

Back 47

1)dizziness
2)drowsiness
3)fatigue
4)bradycardia

Front 48

BB class consultation (4)

Back 48

1)compliance important due to tachycardia and rebound HTN
2)CNS side effects like depression
3)hypoglycemia counseling for DM
4)less ADR's w/ cardioselectives

Front 49

Inderal
a)dosage forms (3)
b)FDA indications (3)
c)PK (2)
d)drug interactions (2)
e)CI

Back 49

a)tablets, SR capsules, solution
b1)angina
b2)HTN
b3)migraine
c)noncardio and crosses BBB
d)cimetidine, propafenone
e)asthma

Front 50

Tenormin
a)FDA indications (2)
b)PK (2)

Back 50

a1)HTN
a2)angina
b1)cardioselective
b2)does NOT cross BBB

Front 51

Tenoretic
a)FDA indications
b)CI
c)what is it?

Back 51

a)HTN
b)sulfonamide allergy
c)atenolol & chlorthalidone

Front 52

Lopressor
a)FDA indications
b)PK (2)
c)drug interactions (2)
d)pt counseling

Back 52

a)HTN, post MI
b1)cardioselective
b2)crosses BBB
c)theophylline, cimetidine
d)take w/ food to incr absorption

Front 53

Toprol XL
a)FDA indications (3)
b)PK (2)
c)drug interactions (2)
d)precautions
e)pt counsel (3)

Back 53

a)HTN, angina, CHF
b)cardioselective, crosses BBB
c)theophylline, cimetidine
d)if need to DC titrate over 1-2wks
e1)w/ CHF pts tell them to monitor wt gain and SOB
e2)take w/ food to incr absorption
e3)do NOT crush but can half tablets

Front 54

Trandate/Normodyne
a)FDA indications
b)PK (2)
c)Pt consultation

Back 54

a)HTN
b)alpha1 blocker AND non-selective BB
c)do not stop medication w/o aid of physician

Front 55

Zebeta (bisprolol)
a)FDA indications
b)PK
c)Pt consultation

Back 55

a)HTN
b)cardioselective
c)do NOT dc abruptly

Front 56

Ziac
a)what is it
b)FDA indications
c)CI
d)Pt consultation (2)

Back 56

a)Bisprolol/HCTZ
b)HTN
c)sulfonamide allergy
d1)take AM
d2)photosensitivity

Front 57

Coreg
a)FDA indications (2)
b)PK
c)Pt consultation

Back 57

a1)HTN start 6.25mg bid****
a2)CHF start 3.125mg bid****
b)non-selective BB and alpha1 blocker
c)take w/ food to decr orthostasis

Front 58

Take what BB w/ food? (2)

Back 58

1)metoprolol (both of em)
2)coreg

Front 59

2 BB for CHF

Back 59

1)coreg
2)toprol XL

Front 60

ACEI class precautions (3)

Back 60

1)pregnancy, nursing
2)impaired renal fxn (use caution, low dose)
3)pts on diuretics, NSAIDs, and/or CHF = higher risk of renal failure if taking ACEI too

Front 61

ACEI class drug interactions (3)

Back 61

1)K+ sparing diuretics/supplements
2)NSAIDs (decr ACEI effect)
3)alters Lithium levels

Front 62

ACEI ADR's (5)

Back 62

1)COUGH (incr bradykinin related)
2)dizziness
3)orthostasis
4)rash
5)ANGIOEDEMA (rare)

Front 63

ACEI pt counseling (3)

Back 63

1)orthostasis counseling
2)report facial swelling/SOB (angioedema)
3)avoid K+ supplements

Front 64

Accupril (quinapril)
a)FDA indications
b)other (2)

Back 64

a1)HTN
b1)lower accupril dose when using diuretics
b2)adjust dose for renal dysfxn

Front 65

Altace (ramipril)
a)FDA indicaions
b)other (2)
c)pt consultation

Back 65

a1)HTN
b1)lower accupril dose when using diuretics
b2)adjust dose for renal dysfxn
c)capsule dosage form can be sprinkled if needed

Front 66

Capoten
a)FDA indications (2)
b)other
c)ADR
d)pt counsel

Back 66

a1)nephropathy and prevention of kidney failure in DM1
a2)incr survival post MI
b)adjust dose in renal dysfxn
c)taste disturbances
d)take on empty stomach 1 hour prior to meals

Front 67

Lotensin
a)generic
b)FDA indications
c)other (2)

Back 67

a)benzapril
b)HTN
c1)use lower lotensin doses when using a diuretic
c2)dose adjustment in renal dysfxn

Front 68

Lotensin HCT
a)FDA indications (2)
b)CI

Back 68

a1)HTN
a2)NOT FOR INITIAL THERAPY
b)sulfonamide allergy

Front 69

Mavik (trandolapril)
a)FDA indications
b)other

Back 69

a)HTN
b)dose adjustment in renal dysfxn and cirrhosis

Front 70

Monopril
a)generic
b)FDA indications (3)
c)pt consultation

Back 70

a)fosinopril
b1)HTN; use lower fosinopril doses when using diuretics
b2)CHF
b3)NO RENAL ADJUSTMENT NEEDED
c)avoid concomitant antacids within 1-2hours

Front 71

Univasc
a)generic
b)FDA indications
c)pt counsultation
d)other

Back 71

a)moexipril
b)HTN
c1)take on empty stomach 1hr prior to meals
d)reduce dose w/ renal dysfxn

Front 72

Vasotec
a)generic
b)dosage forms (2)
c)FDA indications (2)
d)other (2)

Back 72

a)enalapril
b)oral, IV
c)HTN, CHF
d1)use lower vasotec doses if using a diuretic
d2)needs adjustment w/ renal dysfxn

Front 73

Vaseretic
a)generic
b)FDA indications (2)

Back 73

a)enalapril/HCTZ
b1)HTN
b2)NOT FOR INITIAL THERAPY

Front 74

Zestril
a)FDA indications (3)
b)other (2)

Back 74

a1)HTN
a2)CHF
a3)within 24hrs of MI
b1)lower starting doses w/ diuretics
b2)dose adjustment w/ renal dysfxn

Front 75

Zestoretic
a)generic
b)CI
c)pt consultation (2)

Back 75

a)lisinopril/HCTZ
b)sulfonamide allergy
c1)take in AM
c2)photosensitivity

Front 76

Counsel ARB/ACEI on.... (4)

Back 76

1)orthostasis
2)NSAIDs
3)pregnancy
4)K+ supplements/salt substitutes

Front 77

ARB has same CLASS PRECAUTIONS, DRUG INTERACTIONS, ADR, PT CONSULTATION as ACEI

Back 77

n/a

Front 78

Atacand
a)FDA indications (3)

Back 78

1)HTN
2)CHF
3)lower starting doses if volume depleted (diuretics)

Front 79

Avapro (irbesarten)
a)FDA indications (3)

Back 79

1)HTN
2)diabetic nephropathy in DM2
3)lower starting dose if volume depleted (diuretics)

Front 80

Avalide
a)generic
b)pt consultation (3)

Back 80

a)irbesarten/HCTZ
b1)take in AM
b2)photosensitivity
b3)sulfonamide allergy

Front 81

Cozaar
a)generic
b)FDA indication (3)
c)precautions

Back 81

a)losartan
b1)HTN
b2)diabetic nephroapthy in DM2
b3)lower starting dose if volume depleted (diuretics)
c)lower doses w/ hepatic dysfxn

Front 82

Hyzaar
a)generic
b)pt counsel (2)

Back 82

a)losartan/HCTZ
b1)take in AM
b2)photosensitivity

Front 83

Diovan (valsartan)
a)FDA indications (3)
b)titrations (2)

Back 83

a1)HTN
a2)CHF
a3)lower starting dose if volume depleted (diuretics)

b1)addition of diuretic has a greater effect that dose increases beyond 80mg
b2)in CHF titration to 80/160mg bid should be done to highest dose as tolerated

Front 84

Diovan HCT (valsartan/HCTZ)
a)pt consultation (2)

Back 84

a1)take AM
a2)photosensitivity

Front 85

Benicar (olmesartan)
a)FDA indications
b)pt consultation

Back 85

a)HTN
b)prodrug--can cause diarrhea as converted to drug

Front 86

Benicar-HCT when use?

Back 86

substitute this combo product for titrated component

Front 87

Micardis
a)generic
b)FDA indication
c)dosing (3)
d)most effect is seen....

Back 87

a)telmisartan
b)HTN
c1)starting dose is 40mg
c2)titrate to 80mg
c3)if further BP control is needed after 2-4wks on 80mg; add diuretic
d)most effect seen @ 2wks; full effect obtained @ 4wks