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57 Cards in this Set

  • Front
  • Back
Urecholine
a)where it acts
b)mechanism
c)use (3)
d)generic name
a)M3 muscarinic agonist
b)direct acting cholinomimetic that stimulates smooth muscle in bladder
c)post-op/post-partum for bladder voiding, useful in chronic bladder conditions
d)Bethanechol
Isopto Carpine
a)where it acts
b)mechanism
c)uses (2)
d)generic name
a)muscarinic agonist
b)OCULAR direct acting cholinomimetic
c)miotic, facilitate outflow in OPEN angle glaucoma
d)Pilocarpine
Nicotine
a)where it acts
b)mechanism
c)uses
d)dosage forms and which is better and why
a)ganglionic nicotinic receptors
b)ganglionic nicotinic receptor stimulant and depressant
c)smoking cessation
d)buccal and transdermal, transdermal is better b/c it has more sustained levels
Aricept
b)mechanism
c)uses
d)generic name
e)adverse effects
b)Indirect cholinomimetic via reversible cholinesterase inhibitor in CNS
c)alheimer's dementia via incr of ACh
d)Donepizil
e)nausea, anorexia****
Isopto Atropine
a)where it acts
b)mechanism
c)uses
d)generic name
a)muscarinic antagonist
b)OCULAR direct cholinolytic
c)induce mydriasis, cycloplegia for pre/post eye procedures
d)Atropine
Transderm-Scop
a)where it acts
b)mechanism
c)uses
d)generic name
e)counsel point
a)muscarinic antagonist
b)PATCH with high CNS penetration into cerebral cortex and vestibular
c)motion sickness
d)Scopoloamine
e)Applicate patch 4 hours prior to event
Cogentin
a)where it acts
b)mechanism
c)uses
d)generic name
e)adverse effects
a)muscarinic antagonist
b)decr cholinergic tone imbalance due to dopamine deficiency
c)treats muscles rigidity and resting tremor in Parkinson's
d)Benztropine
e)dry mouth, drowsiness
Bentyl
a)where it acts
b)mechanism
c)uses
d)generic name
e)counsel point
a)anticholinergic
b)smooth muscle relaxation in GI tract
c)IBS, cramping
d)dicyclomine
e)admin 30 minutes prior to meal
Levsin, Levbid
a)where it acts
b)mechanism
c)uses
d)dosage forms (and different in sig with them)
e)generic name
f)adverse effects
a)anticholinergic
b)smooth muscle relaxation
c)IBS
d)SL, tablet; SL can be taken before meal prn, tablet is XR take same time each day
e)Hyoscyamine
f)dry mouth, drowsiness
Atrovent
a)where it acts
b)mechanism
c)uses
d)generic name
e)duration of axn
f)schedule?
g)how rapidly it acts?
a)anticholinergic
b)bronchial smooth muscle relaxant
c)COPD
d)Ipatropium
e)4-6 hours
f)use on schedule, not prn
g)NOT rapidly acting
Combivent, Duoneb
a)where it acts
b)mechanism
c)uses
d)generic name
e)difference in the dosage forms
a)anticholinergic & B2 agonist
b)bronchial smooth muscle relaxation
c)COPD
d)ipatropiun & albuterol
e)combivent is MDI, DuoNeb is nebulized
Spiriva
a)where it acts
b)mechanism
c)uses
d)generic name
e)administration (2)
a)M3 anticholinergic
b)bronchial smooth muscle relaxant
c)COPD
d)tiotropium
e)once daily, use handihaler
Dopamine
a)where it acts
b)mechanism
c)uses
d)generic name
e)administration
a)stimulate dopamine and B1 receptors
b)incr renal blood flow, incr systolic BP and heart rate
c)hemodynamic imbalances, cardic/shock conditions
d)n/a
e)by continuous IV b/c half-life is short
Sinemet/Sinemet CR
b)mechanism
c)uses
d)generic name
e)Sinemet CR special features
f)dose difference b/w reg and CR
b)Carbidopa is a dopa decarboxlyase inhibitor making it so that L-dopa to dopamine not done in periphery
c)Parkinson's
d)L-dopa, Carbidopa
e)CR tablet that can be broken
f)CR will ALWAYS have higher doses
Dobutrex
a)where it acts
b)uses
c)generic name
d)administration
a)stim B1-receptors
b)cardiac decompensation, CHF
c)Dobutamine
d)continuous IV b/c short half-life
Naphcon, Privine
a)where it acts
c)uses
d)generic name
d)difference in dosage forms
e)main side effect
a)Alpha 1 adrenergic agonist
b)ocular vasoconstrictor, topical nasal decongestant
c)naphazoline
d)Naphcon is ocular, Privine is nasal
e)rebound congestion so limit use to 3 days
OcuClear, Afrin
a)where it acts
b)uses
d)generic name
e)difference in dosage forms
f)main side effect
a)alpha 1 adrenergic agonist
b)ocular vasoconstriction, topical nasal decongestant
c)oxymetazoline
d)Ocuclear is ocular, Afrin is nasal
e)rebound congestion so limit use to 3 days
Sudafed-PE, Neosynephrine
a)where it acts
b)uses
c)generic name
d)difference in dosage forms
e)main side effects
a)alpha 1 adrenergic agonist
b)oral decongestant, topical nasal decongestant
c)phenylephrine
d)Sudafed is oral, neosynephrine is nasal
e)highest incidence of rebound congestion is seen w/ PE
Epinephrine
a)where it acts
b)mechanism
c)uses
d)BRAND names (2)
a)alpha and beta adrenergic receptor agonist
b)vasoconstriction, bronchodilation
c)Type 1 hypersensitivity rxns
d)EpiPen, EpiPen Jr
Catapres
a)where it acts
b)mechanism
c)uses
d)adverse effects
e)why is compliance essential
f)2 dosage forms
g)generic name
a)CNS alpha 2 receptor agonist
b)inhibits central sympathetic outflow
c)hypertension
d)dry mouth, drowsiness, dizziness
e)b/c of rebound hypertension
f)transdermal, oral
g)clonidine
Alphagan P
a)where it acts
b)mechanism
c)uses
d)generic name
a)alpha 2 receptor agonist
b)decrease aqueous humor production and stimulates outflow
c)OPEN angle glaucoma
d)Brimonidine
Proventil
a)where it acts
b)mechanism
c)use
d)generic name
e)adverse effects
f)counseling points (2)
g)usual dosage
a)Beta-2 agonist
b)bronchodilator that relaxes broncial, uterine, vasular smooth muscle
c)relief and prevention of bronchospasm
d)albuterol
e)nervousness, tremor, tachycardia
f)tell how to use inhaler, look @ refill history to determine asthma control
g)1-2 puffs q4-6h prn
Serevent
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
a)Beta-2 agonist
b)bronchodilator
c)Long Acting maintenance treatment of asthma, NOT for rapid relief via Diskus Device
d)salmeterol
e)1 inhalation q12h
Maxair
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
a)beta-2 agonist
b)bronchodilator
c)relief of bronchospasm via Autoinhaler (breath activated)
d)pirbuterol
e)1-2 inhalations q4-6h prn
Xopenex
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)dosage forms
g)side effects
h)____ isomer is used
a)beta-2 agonist
b)short acting bronchodilator
c)relief of bronchospasm
d)levalbuterol
e)1 via nebulizer tid
f)aerosol and nebulizer
g)same as albuterol
h)R-albuterol
Brethine
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)unlabeled use
g)what limits its use
a)beta-2 agonist
b)bronchodilator
c)relief of bronchospasm
d)terbutaline
e)5mg tid
f)tocolytic agent to treat preterm labor
g)systemic SEs
Alupent
a)where it acts
b)mechanism
c)use
d)generic name
a)beta-2 agonist
b)bronchodilator (for kids over 12yo)
c)asthma
d)metaproterenol
Adderall/XR
b)mechanism
c)use (2)
d)generic name
e)usual dosage
f)special thing for XR
b)CNS stimulant
c)narcolepsy, ADHD
d)Amphetamine
e)5-60mg qd for XR, 5-60mg bid for regular
f)XR capsules can be opened and sprinkled on applesauce
Concerta
b)mechanism
c)use
d)generic name
e)usual dosage
b)CNS stimulant via indirect adrenomimetic
c)ADD
d)methyphenidate
e)18mg qd; b/c long acting
Ritalin
b)mechanism
c)use (2)
d)generic name
e)usual dosage
b)CNS stimulant
c)ADD, narcolepsy
d)methylphenidate
e)5mg bid
Strattera
b)mechanism
c)use
d)generic name
e)usual dosage
f)special thing about it
b)CNS stimulant
c)ADHD
d)atomoextine
e)80mg in divided doses
f)first non-stimulant approved for ADHD
Sudafed
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)schedule and max purchase amt
g)rebound congestion?
a)alpha1 agonist
b)decongestant
c)nasal congestion
d)pseudoephedrine
e)60mg q4-6 prn
f)C5, 9g per 30 days
g)None if you use the oral systemic type, yes w/ topical
Amitriptylline
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)problems (2)
a)potentiates NE & 5-HT by blocking reuptake
b)tricyclic antidepressant
c)treat depression
d)Elavil
e)40-150mg qhs
f)high protein binding so problematic w/ overdose, lotsa SEs
Tofranil
b)mechanism
c)use (2)
d)generic name
e)usual dosage
f)problems
b)tricyclic antidepressant
c)depression, enuresis
d)imipramine
e)50-150mg qd
f)overdose due to protein binding
Pamelor
b)mechanism
c)use
d)generic name
e)usual dosage
f)problems
b)tricyclic antidepressant
c)depression (less sedating than amitriptylline)
d)Nortriptylline
e)75-150mg qd
f)overdose due to protein binding
Nardil
b)mechanism
c)use
d)generic name
f)problems (2)
b)Nonselective MAOI
c)severe depression that requires close monitoring
d)phenelzine
f)no tyramine foods (causes HTN crisis), interacts w/ drugs that interact w/ MAO
Flomax
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
a)alpha-1a antagonist
b)relaxes prostate gland and bladder neck
c)BPH
d)Tamsulosin
e)0.4-0.8mg qd after same meal every day to limit SEs
Minipres
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)problems
g)counsel points (2)
a)alpha-1 antagonist
b)antihypertensive
c)HTN
d)Prazosin
e)6-15mg tid
f)adherence important b/c of alpha receptor downregulation
g)take hs b/c of orthostatic hypotension, start dose low and incr b/c tolerance will occur
Cardura/XL
a)where it acts
b)mechanism (2)
c)use (2)
d)generic name
e)usual dosage
f)problems
g)counsel points (2)
a)alpha-1 antagonist
b)dilate arterioles and veins, relax bladder neck and prostate
c)HTN, BPH
d)Doxazosin
e)1-4mg qd
f)adherence important b/c of alpha receptor downregulation
g)take XL @ any time, regular @ hs
Hytrin
a)where it acts
c)use
d)generic name
e)usual dosage
f)problems
a)alpha blocker
c)BPH, HTN
d)Terzosin
e)1-5mg qd
f)adherence important b/c of alpha receptor downregulation
Lopressor/Toprol XL
a)where it acts
c)use (4)
d)generic name
e)usual dosage
f)problems (2)
a)beta-1 blocker CARDIOSELECTIVE
c)HTN, MI, angina pectoris, stable CHF
d)metoprolol
e)100-450mg qd
f)adherence important b/c of rebound HTN, loss of selectivity @ high doses
Inderal/LA
a)where it acts
c)use (3)
d)generic name
e)usual dosage
f)problems (2)
a)beta-blocker NONselective
c)HTN, arrhythmias, angina pectoris
d)propanolol
e)80mg bid for reg, 60-160mg qd for LA
f)adherence important b/c of rebound HTN, CI is bronchial asthma b/c block B2 receptors
Betoptic
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
a)beta-1** blocker
b)decreases aqueous humor production
c)open angle glaucoma
d)Betaxolol
e)1-2 drops bid
Tenormin
a)where it acts
c)use (2)
d)generic name
e)usual dosage
f)problems
a)Beta blocker (BETA1, CARDIOSELECTIVE)
c)HTN, angina pectoris
d)Atenolol
e)50-200mg qd
f)adherence important b/c of rebound HTN
Timoptic
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)CI
a)NONselective Beta Blocker
b)decr aqueous humor
c)open angle glaucoma
d)Timolol
e)1 drop bid
f)broncial asthma b/c blocks Beta-2
Cosopt
a)where it acts (2)
b)mechanism
c)use
d)generic name
e)usual dosage
f)CI
a)beta blocker, carbonic anhydrase inhibitor
b)decrease aqueous humor production
c)open angle glaucoma
d)dorzolamide, timolol
e)1 drop bid
f)bronchial asthma b/c blocks beta-2
Normodyne/Trandate
a)where it acts (2)
c)use
d)generic name
e)usual dosage
f)SEs/counsel
a)alpha-1 blocker and beta-blocker
c)HTN
d)Lebataolol
e)200-400mg bid
f)dizziness, so start w/ low doses and titrate slowly
Coreg
a)where it acts
b)mechanism
c)use (2)
d)generic name
e)usual dosage
f)counsel points (2)
a)NONselective beta blocker, alpha-1 blocker
c)HTN, CHF
d)carvedilol
e)HTN 6.25mg bid, CHF 3.125mg bid
f)take w/ food to decr orthostatic hypotension, spend time w/ pt to discuss SEs
Reserpine
b)mechanism
c)use
d)generic name
f)adverse effects
g)when to use
b)depletes stores of catecholamine and 5-HT
c)HTN
d)n/a
f)long half life so LOTS of bad side effects
g)If last resort HTN drug
Ditropan/XL
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)SEs (3)
anti-muscarinic
b)urinary antisposmodic that relaxes bladder SM
c)overactive bladder
d)oxybutnin
e)XL 5mg qd, reg 5mg tid
f)dry mouth, dizziness, constipation
Detrol/LA
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)SEs (3)
a)competitive antimuscarinic
b)urinary antispasmodic
c)overactive bladder
d)tolterodine
e)reg 2mg bid, LA 4mg qd
f)dry mouth, dizziness, constipation
Beta1 selective beta blockers (4)
1)betaxolol
2)atenolol
3)metoprolol
4)acebutolol
Beta-blockers CI what drugs
Ca channel blockers
Beta blocker, Ca channel blocker interaction mechanism (3)
1)additive hypotension/bradycardia
2)(-) inotropic effects
3)slowed AV condution
Beta blockers w/ ____ is the worst then ___ then ____
VERAPAMIL
diltiazem
amlodipine
Beta blockers w/ Ca channel blockers risk factor...
CHF
Monitor/educate patients taking beta blocker/Ca channel blocker on... (5)
1)dizzyness
2)dyspnea
3)lethargy/fatigue
4)pulse rate
5)BP