Practice3 Drugs Test 1 Set 1

Front 1

Urecholine
a)where it acts
b)mechanism
c)use (3)
d)generic name

Back 1

a)M3 muscarinic agonist
b)direct acting cholinomimetic that stimulates smooth muscle in bladder
c)post-op/post-partum for bladder voiding, useful in chronic bladder conditions
d)Bethanechol

Front 2

Isopto Carpine
a)where it acts
b)mechanism
c)uses (2)
d)generic name

Back 2

a)muscarinic agonist
b)OCULAR direct acting cholinomimetic
c)miotic, facilitate outflow in OPEN angle glaucoma
d)Pilocarpine

Front 3

Nicotine
a)where it acts
b)mechanism
c)uses
d)dosage forms and which is better and why

Back 3

a)ganglionic nicotinic receptors
b)ganglionic nicotinic receptor stimulant and depressant
c)smoking cessation
d)buccal and transdermal, transdermal is better b/c it has more sustained levels

Front 4

Aricept
b)mechanism
c)uses
d)generic name
e)adverse effects

Back 4

b)Indirect cholinomimetic via reversible cholinesterase inhibitor in CNS
c)alheimer's dementia via incr of ACh
d)Donepizil
e)nausea, anorexia****

Front 5

Isopto Atropine
a)where it acts
b)mechanism
c)uses
d)generic name

Back 5

a)muscarinic antagonist
b)OCULAR direct cholinolytic
c)induce mydriasis, cycloplegia for pre/post eye procedures
d)Atropine

Front 6

Transderm-Scop
a)where it acts
b)mechanism
c)uses
d)generic name
e)counsel point

Back 6

a)muscarinic antagonist
b)PATCH with high CNS penetration into cerebral cortex and vestibular
c)motion sickness
d)Scopoloamine
e)Applicate patch 4 hours prior to event

Front 7

Cogentin
a)where it acts
b)mechanism
c)uses
d)generic name
e)adverse effects

Back 7

a)muscarinic antagonist
b)decr cholinergic tone imbalance due to dopamine deficiency
c)treats muscles rigidity and resting tremor in Parkinson's
d)Benztropine
e)dry mouth, drowsiness

Front 8

Bentyl
a)where it acts
b)mechanism
c)uses
d)generic name
e)counsel point

Back 8

a)anticholinergic
b)smooth muscle relaxation in GI tract
c)IBS, cramping
d)dicyclomine
e)admin 30 minutes prior to meal

Front 9

Levsin, Levbid
a)where it acts
b)mechanism
c)uses
d)dosage forms (and different in sig with them)
e)generic name
f)adverse effects

Back 9

a)anticholinergic
b)smooth muscle relaxation
c)IBS
d)SL, tablet; SL can be taken before meal prn, tablet is XR take same time each day
e)Hyoscyamine
f)dry mouth, drowsiness

Front 10

Atrovent
a)where it acts
b)mechanism
c)uses
d)generic name
e)duration of axn
f)schedule?
g)how rapidly it acts?

Back 10

a)anticholinergic
b)bronchial smooth muscle relaxant
c)COPD
d)Ipatropium
e)4-6 hours
f)use on schedule, not prn
g)NOT rapidly acting

Front 11

Combivent, Duoneb
a)where it acts
b)mechanism
c)uses
d)generic name
e)difference in the dosage forms

Back 11

a)anticholinergic & B2 agonist
b)bronchial smooth muscle relaxation
c)COPD
d)ipatropiun & albuterol
e)combivent is MDI, DuoNeb is nebulized

Front 12

Spiriva
a)where it acts
b)mechanism
c)uses
d)generic name
e)administration (2)

Back 12

a)M3 anticholinergic
b)bronchial smooth muscle relaxant
c)COPD
d)tiotropium
e)once daily, use handihaler

Front 13

Dopamine
a)where it acts
b)mechanism
c)uses
d)generic name
e)administration

Back 13

a)stimulate dopamine and B1 receptors
b)incr renal blood flow, incr systolic BP and heart rate
c)hemodynamic imbalances, cardic/shock conditions
d)n/a
e)by continuous IV b/c half-life is short

Front 14

Sinemet/Sinemet CR
b)mechanism
c)uses
d)generic name
e)Sinemet CR special features
f)dose difference b/w reg and CR

Back 14

b)Carbidopa is a dopa decarboxlyase inhibitor making it so that L-dopa to dopamine not done in periphery
c)Parkinson's
d)L-dopa, Carbidopa
e)CR tablet that can be broken
f)CR will ALWAYS have higher doses

Front 15

Dobutrex
a)where it acts
b)uses
c)generic name
d)administration

Back 15

a)stim B1-receptors
b)cardiac decompensation, CHF
c)Dobutamine
d)continuous IV b/c short half-life

Front 16

Naphcon, Privine
a)where it acts
c)uses
d)generic name
d)difference in dosage forms
e)main side effect

Back 16

a)Alpha 1 adrenergic agonist
b)ocular vasoconstrictor, topical nasal decongestant
c)naphazoline
d)Naphcon is ocular, Privine is nasal
e)rebound congestion so limit use to 3 days

Front 17

OcuClear, Afrin
a)where it acts
b)uses
d)generic name
e)difference in dosage forms
f)main side effect

Back 17

a)alpha 1 adrenergic agonist
b)ocular vasoconstriction, topical nasal decongestant
c)oxymetazoline
d)Ocuclear is ocular, Afrin is nasal
e)rebound congestion so limit use to 3 days

Front 18

Sudafed-PE, Neosynephrine
a)where it acts
b)uses
c)generic name
d)difference in dosage forms
e)main side effects

Back 18

a)alpha 1 adrenergic agonist
b)oral decongestant, topical nasal decongestant
c)phenylephrine
d)Sudafed is oral, neosynephrine is nasal
e)highest incidence of rebound congestion is seen w/ PE

Front 19

Epinephrine
a)where it acts
b)mechanism
c)uses
d)BRAND names (2)

Back 19

a)alpha and beta adrenergic receptor agonist
b)vasoconstriction, bronchodilation
c)Type 1 hypersensitivity rxns
d)EpiPen, EpiPen Jr

Front 20

Catapres
a)where it acts
b)mechanism
c)uses
d)adverse effects
e)why is compliance essential
f)2 dosage forms
g)generic name

Back 20

a)CNS alpha 2 receptor agonist
b)inhibits central sympathetic outflow
c)hypertension
d)dry mouth, drowsiness, dizziness
e)b/c of rebound hypertension
f)transdermal, oral
g)clonidine

Front 21

Alphagan P
a)where it acts
b)mechanism
c)uses
d)generic name

Back 21

a)alpha 2 receptor agonist
b)decrease aqueous humor production and stimulates outflow
c)OPEN angle glaucoma
d)Brimonidine

Front 22

Proventil
a)where it acts
b)mechanism
c)use
d)generic name
e)adverse effects
f)counseling points (2)
g)usual dosage

Back 22

a)Beta-2 agonist
b)bronchodilator that relaxes broncial, uterine, vasular smooth muscle
c)relief and prevention of bronchospasm
d)albuterol
e)nervousness, tremor, tachycardia
f)tell how to use inhaler, look @ refill history to determine asthma control
g)1-2 puffs q4-6h prn

Front 23

Serevent
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage

Back 23

a)Beta-2 agonist
b)bronchodilator
c)Long Acting maintenance treatment of asthma, NOT for rapid relief via Diskus Device
d)salmeterol
e)1 inhalation q12h

Front 24

Maxair
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage

Back 24

a)beta-2 agonist
b)bronchodilator
c)relief of bronchospasm via Autoinhaler (breath activated)
d)pirbuterol
e)1-2 inhalations q4-6h prn

Front 25

Xopenex
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)dosage forms
g)side effects
h)____ isomer is used

Back 25

a)beta-2 agonist
b)short acting bronchodilator
c)relief of bronchospasm
d)levalbuterol
e)1 via nebulizer tid
f)aerosol and nebulizer
g)same as albuterol
h)R-albuterol

Front 26

Brethine
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)unlabeled use
g)what limits its use

Back 26

a)beta-2 agonist
b)bronchodilator
c)relief of bronchospasm
d)terbutaline
e)5mg tid
f)tocolytic agent to treat preterm labor
g)systemic SEs

Front 27

Alupent
a)where it acts
b)mechanism
c)use
d)generic name

Back 27

a)beta-2 agonist
b)bronchodilator (for kids over 12yo)
c)asthma
d)metaproterenol

Front 28

Adderall/XR
b)mechanism
c)use (2)
d)generic name
e)usual dosage
f)special thing for XR

Back 28

b)CNS stimulant
c)narcolepsy, ADHD
d)Amphetamine
e)5-60mg qd for XR, 5-60mg bid for regular
f)XR capsules can be opened and sprinkled on applesauce

Front 29

Concerta
b)mechanism
c)use
d)generic name
e)usual dosage

Back 29

b)CNS stimulant via indirect adrenomimetic
c)ADD
d)methyphenidate
e)18mg qd; b/c long acting

Front 30

Ritalin
b)mechanism
c)use (2)
d)generic name
e)usual dosage

Back 30

b)CNS stimulant
c)ADD, narcolepsy
d)methylphenidate
e)5mg bid

Front 31

Strattera
b)mechanism
c)use
d)generic name
e)usual dosage
f)special thing about it

Back 31

b)CNS stimulant
c)ADHD
d)atomoextine
e)80mg in divided doses
f)first non-stimulant approved for ADHD

Front 32

Sudafed
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)schedule and max purchase amt
g)rebound congestion?

Back 32

a)alpha1 agonist
b)decongestant
c)nasal congestion
d)pseudoephedrine
e)60mg q4-6 prn
f)C5, 9g per 30 days
g)None if you use the oral systemic type, yes w/ topical

Front 33

Amitriptylline
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)problems (2)

Back 33

a)potentiates NE & 5-HT by blocking reuptake
b)tricyclic antidepressant
c)treat depression
d)Elavil
e)40-150mg qhs
f)high protein binding so problematic w/ overdose, lotsa SEs

Front 34

Tofranil
b)mechanism
c)use (2)
d)generic name
e)usual dosage
f)problems

Back 34

b)tricyclic antidepressant
c)depression, enuresis
d)imipramine
e)50-150mg qd
f)overdose due to protein binding

Front 35

Pamelor
b)mechanism
c)use
d)generic name
e)usual dosage
f)problems

Back 35

b)tricyclic antidepressant
c)depression (less sedating than amitriptylline)
d)Nortriptylline
e)75-150mg qd
f)overdose due to protein binding

Front 36

Nardil
b)mechanism
c)use
d)generic name
f)problems (2)

Back 36

b)Nonselective MAOI
c)severe depression that requires close monitoring
d)phenelzine
f)no tyramine foods (causes HTN crisis), interacts w/ drugs that interact w/ MAO

Front 37

Flomax
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage

Back 37

a)alpha-1a antagonist
b)relaxes prostate gland and bladder neck
c)BPH
d)Tamsulosin
e)0.4-0.8mg qd after same meal every day to limit SEs

Front 38

Minipres
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)problems
g)counsel points (2)

Back 38

a)alpha-1 antagonist
b)antihypertensive
c)HTN
d)Prazosin
e)6-15mg tid
f)adherence important b/c of alpha receptor downregulation
g)take hs b/c of orthostatic hypotension, start dose low and incr b/c tolerance will occur

Front 39

Cardura/XL
a)where it acts
b)mechanism (2)
c)use (2)
d)generic name
e)usual dosage
f)problems
g)counsel points (2)

Back 39

a)alpha-1 antagonist
b)dilate arterioles and veins, relax bladder neck and prostate
c)HTN, BPH
d)Doxazosin
e)1-4mg qd
f)adherence important b/c of alpha receptor downregulation
g)take XL @ any time, regular @ hs

Front 40

Hytrin
a)where it acts
c)use
d)generic name
e)usual dosage
f)problems

Back 40

a)alpha blocker
c)BPH, HTN
d)Terzosin
e)1-5mg qd
f)adherence important b/c of alpha receptor downregulation

Front 41

Lopressor/Toprol XL
a)where it acts
c)use (4)
d)generic name
e)usual dosage
f)problems (2)

Back 41

a)beta-1 blocker CARDIOSELECTIVE
c)HTN, MI, angina pectoris, stable CHF
d)metoprolol
e)100-450mg qd
f)adherence important b/c of rebound HTN, loss of selectivity @ high doses

Front 42

Inderal/LA
a)where it acts
c)use (3)
d)generic name
e)usual dosage
f)problems (2)

Back 42

a)beta-blocker NONselective
c)HTN, arrhythmias, angina pectoris
d)propanolol
e)80mg bid for reg, 60-160mg qd for LA
f)adherence important b/c of rebound HTN, CI is bronchial asthma b/c block B2 receptors

Front 43

Betoptic
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage

Back 43

a)beta-1** blocker
b)decreases aqueous humor production
c)open angle glaucoma
d)Betaxolol
e)1-2 drops bid

Front 44

Tenormin
a)where it acts
c)use (2)
d)generic name
e)usual dosage
f)problems

Back 44

a)Beta blocker (BETA1, CARDIOSELECTIVE)
c)HTN, angina pectoris
d)Atenolol
e)50-200mg qd
f)adherence important b/c of rebound HTN

Front 45

Timoptic
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)CI

Back 45

a)NONselective Beta Blocker
b)decr aqueous humor
c)open angle glaucoma
d)Timolol
e)1 drop bid
f)broncial asthma b/c blocks Beta-2

Front 46

Cosopt
a)where it acts (2)
b)mechanism
c)use
d)generic name
e)usual dosage
f)CI

Back 46

a)beta blocker, carbonic anhydrase inhibitor
b)decrease aqueous humor production
c)open angle glaucoma
d)dorzolamide, timolol
e)1 drop bid
f)bronchial asthma b/c blocks beta-2

Front 47

Normodyne/Trandate
a)where it acts (2)
c)use
d)generic name
e)usual dosage
f)SEs/counsel

Back 47

a)alpha-1 blocker and beta-blocker
c)HTN
d)Lebataolol
e)200-400mg bid
f)dizziness, so start w/ low doses and titrate slowly

Front 48

Coreg
a)where it acts
b)mechanism
c)use (2)
d)generic name
e)usual dosage
f)counsel points (2)

Back 48

a)NONselective beta blocker, alpha-1 blocker
c)HTN, CHF
d)carvedilol
e)HTN 6.25mg bid, CHF 3.125mg bid
f)take w/ food to decr orthostatic hypotension, spend time w/ pt to discuss SEs

Front 49

Reserpine
b)mechanism
c)use
d)generic name
f)adverse effects
g)when to use

Back 49

b)depletes stores of catecholamine and 5-HT
c)HTN
d)n/a
f)long half life so LOTS of bad side effects
g)If last resort HTN drug

Front 50

Ditropan/XL
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)SEs (3)

Back 50

anti-muscarinic
b)urinary antisposmodic that relaxes bladder SM
c)overactive bladder
d)oxybutnin
e)XL 5mg qd, reg 5mg tid
f)dry mouth, dizziness, constipation

Front 51

Detrol/LA
a)where it acts
b)mechanism
c)use
d)generic name
e)usual dosage
f)SEs (3)

Back 51

a)competitive antimuscarinic
b)urinary antispasmodic
c)overactive bladder
d)tolterodine
e)reg 2mg bid, LA 4mg qd
f)dry mouth, dizziness, constipation

Front 52

Beta1 selective beta blockers (4)

Back 52

1)betaxolol
2)atenolol
3)metoprolol
4)acebutolol

Front 53

Beta-blockers CI what drugs

Back 53

Ca channel blockers

Front 54

Beta blocker, Ca channel blocker interaction mechanism (3)

Back 54

1)additive hypotension/bradycardia
2)(-) inotropic effects
3)slowed AV condution

Front 55

Beta blockers w/ ____ is the worst then ___ then ____

Back 55

VERAPAMIL
diltiazem
amlodipine

Front 56

Beta blockers w/ Ca channel blockers risk factor...

Back 56

CHF

Front 57

Monitor/educate patients taking beta blocker/Ca channel blocker on... (5)

Back 57

1)dizzyness
2)dyspnea
3)lethargy/fatigue
4)pulse rate
5)BP