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41 Cards in this Set

  • Front
  • Back

What are arteries otherwise known as?

Resistance vessels

What are capillaries otherwise known as?

Exchange vessels

What is the source of energy that propels the blood?

Muscular contraction

What are veins otherwise known as?

Capacitance vessels

How is flow restricted to one direction only?

Valves at the inflow and outflow points of the ventricles

How is the pump refilled after contraction?

By the atria passively leaking blood, and then actively squeezing blood, into the ventricles

How are the layers of myocardium arranged?

Sub endocardial myocytes are arranged in a superior-interior orientation. As you go up the layers, the myocytes twist 180 degrees, ending up at sup-inf again at the subepicardial myocytes

Which mechanism couples electricity and tension in the heart?

Excitation contraction coupling

Write the equation relating tension and pressure

Laplaces law

Why is laplaces law different in the ventricles to in the vessels?

Because the ventricles are a different shape to the vessels (cone vs rod)

What is the vicious cycle of maladaptive hypertrophy?

If a ventricle grows, it's radius increases. According to laplaces law, this will require a corresponding increase in tension to maintain the pressure. To increase tension, the heart grows more, further increasing radius and starting the cycle again

How are pressure and flow related?

Ohms law

What provides resistance in the heart?

Valves

What is an incompetent valve?

A valve that won't fully close, which may cause some blood to leak backwards

What is a stenosed valve?

A valve that won't fully open, leading to increased resistance and a corresponding higher pressure to maintain flow

What is the isovolumetric phase?

The phases of the cardiac cycle where both valves of a ventricle are closed, so the volume remains constant

What is the purpose of the isovolumetric phase?

To ensure that the AV valve is closed before the semi lunar valve opens, to prevent backflow

True or false - atrial systole takes place within ventricular diastole?

True

During atrial contraction, which valves are open?

AV only

During ventricular systole, which valves are open?

Semilunar only

What is the first phase of ventricular diastole?

Isovolumetric relaxation - the ventricular pressure is between aortic and atrial pressure, so all valves are closed. The ventricle pressure decreases without a change in volume

When do isovolumetric phases occur with relation to pressure?

When ventricular pressure is between arterial and atrial pressure

What is the second phase of ventricular diastole?

The filling phase, where ventricular pressure drops so low it sucks blood in through the AV valve. This is called passive recoil

What is the first phase of ventricular systole?

Isovolumetric contraction - the ventricle pressure increases without an accompanying change in volume

What is the second phase of ventricular systole?

Ejection into the aorta

When do the two heart sounds occur?

When the valves close at the start of the isovolumetric phases

Which is lub and which is dub?

Lub is AV closure at the start of isovolumetric contraction



Dub is semilunar closure at the start of isovolumetric relaxation

How much do the atria contribute to ventricular filling in young people?

10-20%

How much do the atria contribute to ventricular filling in the elderly?

50%

Why is atrial fibrillation a more dangerous condition in the elderly than young people?

Because as you get older, your recoil and passive ventricular filling decrease so the atria contribute more to ventricular filling

Draw a diagram of changing ventricular pressure during the cardiac cycle

Draw a diagram of changing ventricular volume during the cardiac cycle

What causes central venous pressure to rise?

Atrial contraction


A-V valve closure


Atrial filling

What causes CVP to fall during the cardiac cycle?

Atrial relaxation


AV valve opening

Why is CVP linked to atrial pressure?

Because there is no valve linking vena cavae to RA

Draw a labelled diagram to show jugular venous pressure in response to the cardiac cycle

What causes the A wave on a JVP curve?

Atrial systole

What causes the C wave on a jugular pressure graph?

Closure of the tricuspid valve - can hear the lub at this point

What causes the X descent?

Atrial relaxation

What causes the V ascent?

Atrial filling during ventricular systole

What causes the Y descent on a JVP graph?

The opening of the tricuspid valve