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27 Cards in this Set
- Front
- Back
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penicillin G
penicillin V |
Staphylococcus aureus, Streptococcus pneumonia (MIC 0.1-1 mcg/ml)
Enterococcus (synergy with aminoglycoside) Pen G (Neisseria meningitidis) |
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nafcillin, oxacillin
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Staphylococcus aureus
Streptococcus pneumonia |
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ampicillin/sulbactam
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Staphylococcus aureus, Streptococcus pneumonia, gram negative (E. coli, Klebsiella, Haemophilus influenza) and anaerobes (Bacteroides)
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ticarcillin/potassium clavulanate
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Staphylococcus aureus, Streptococcus pneumonia, greater gram negative (E. coli, Klebsiella, Haemophilus influeza, Pseudomonas) and anaerobes (Bacteroides)
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1st generation Cephalosporin
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gram positive (Staphylococcus, Beta-hemolytic streptococcus)
minimal gram negative (E. coli, Klebsiella) |
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2nd generation Cephalosporin
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Equal gram neg/pos coverage
gram positive (Staphylococcus, beta-hemolytic streptococcus, Streptococcus pneumonia) gram negative (Haemophilus influenza) anaerobes - some activity against Bacteroides and Clostridium sp |
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3rd generation Cephalosporin
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greater gram negative than gram positive coverage
gram positive (beta-hemolytic streptococcus, streptococcus pneumonia) gram negative (E. coli, Haemophilus influenza, Proteus mirabilis) anaerobes - some activity against Bacteroides and Clostridium sp |
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4th generation Cephalosporin
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similiar to 3rd generation ceph. coverage
very good coverage for Pseudomonas aeruginosa and limited anaerobic coverage |
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Macrolides
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gram positive (Staphylococcal and Streptococcal sp)
gram negative (Haemophilus influenza, Moraxella, Legionella and Neisseria) atypical (Mycoplasma pneumoniae, Chlamydia) |
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Tetracyclines
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gram positive (Staphylococcal and Streptococcal sp)
gram negative (Haemophilus influenza, E.coli, Klebsiella and Neisseria sp.) atypical (mycoplasma pneumonia, chlamydia) other (Rickettsia, Borrelia) |
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Nitrofurantoin
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UTIs caused by susceptible gram positive (more) and gram negative organisms; not so much againt Pseudomonas, Serratia, and Proteus
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Fluoroquinolones
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gram positive (Staphylococcus aureus, Streptococusi aeroginosa)
gram negative (E.coli, Klebsiella sp, H. influenza, Pseudomonas aeruginosa) atypical (mycoplasma pneumoniae) - Levo anaerobic (Bacteroides sp, Fusobacterium sp - moxi/gati) Streptococci pneumoniae - levo/moxi/gati 1st DOC for CAP |
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Glycopeptides
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Severe Staph and Strept sp. including MRSA
coagulase (-) staph and enterococcus faecium/faecalis. Use in combo with aminoglycoside for strept and staph endocarditis. Life threatening infections of lower respiratory tract, bone, skin, and skin structure and septicemia |
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Aminoglycosides
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gram positive (S. aureus, Enterococcus sp. (faecalis, faecium)
gram negative (E. coli, Klebsiella, Proteus, Enterobacter, Pseudomonas aeruginosa, Serratia sp.) other (Salmonella) not effective for group D Streptococcus and anaerobes Always used in synergy |
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Sulfonamides
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gram positive (Staphyloccus aureus)
gram negative (H. influenza, E. coli, Klebsiella, Proteus) other (Toxoplasmosis, Malaria) |
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trimethoprim/sulfamethoxazole
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gram positive (Staph aureus, S. pneumoniae)
gram negative (H. influenza, E.coli, Klebsiella, Proteus, enterobacter sp.) other (PCP, cholera, salmonella) |
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Lincosamides
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gram positive (staph. aureus, strep pneumoniae)
(not used alone unless pt. is allergic to other agents) anaerobes (Bacteroides, actinomyces, peptococcus, peptostreptococcus) |
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Metronidazole
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anaerobes (Bacteroides, Actinomyces, Peptooccus, Peptostretococcus, clostridium)
other (H. pylori, and anaerobic protozoa including trichomonas and giardia sp) |
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Carbapenems
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gram positive (staph aureus (MSSA), strept viridans and pyogenes, enterococcus faecalis)
gram negative (E.coli, Klebsiella, proteus, H. influenza, Pseudomonas aeruginosa, Acinetobacter sp. serratia marcesens) anaerobes (Bacteroides, peptococcus, peptostretpococcus, clostridium) meropenem approved for bacterial meningitis in children (>3 month old) s. pneumoniae, H. influ, and N. meningitides |
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Chloramphenicol
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gram positive (staph aureus, enterococcus faecium/faecalis (VRE))
gram negative (H. influ, N. meningitides) anaerobes (Bacteroides) other (Rickettsia, Salmonella) |
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Rifampin
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treatment and prevention of TB, leprosy, meningococcal meningitis and H. influenza prophylaxis. Used in combo with other anti-infectives in the treatment of staph infections for synergy
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Streptogramins
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complicated skin/skin structure infections caused by methicillin susceptible and methicillin resistant staph aureus or strept pyogenes
life-threatening VRE infections |
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Oxalodinones
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complicated skin/skin structure infections caused by methicillin susceptible/methicillin resistant staph aureus or strept pyogenes
nosocomial pneumonia caused by staph aureus (MSSA or MRSA) or s. pneumoniae proposed for DOC of VAP induced VRSA linezolid has good lung penitrations |
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Monobactams
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gram negative (p. aeruginosa, E. coli, Enterobacter, Klebsiella, proteus, serratia and haeomophilus sp.)
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Lipopeptides
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complicated skin infections caused by MSSA, strept pyogenes and vacomycin susceptible strains of enterococcus faecalis. bloodstream infections including those with right-sided endocarditis, caused by MSSA and MRSA
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Ketolides
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CAP (strept pneumoniae, haemophilus influ, moraxella catarrhalis, chlamydophila pneumoniae, or mycoplasma pneumoniae)
FDA for bronchitis, acute sinusitis |
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Glycylcycline
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treatment of skin infections caused by MSSA, E. coli, S pyogenes, Bacteroides fragilis, and vancomycin-sensitive entorococcus faecalis
treatment of complicated intra-abdominal infections. Other organisms that have demonstrated in-vivo and in-vitro activity: E. coli, klebsiella pneumoniae, enterobacter cloacae, bacteroides sp. potent but no effect on pseud aueruginosa |
