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30 Cards in this Set
- Front
- Back
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Usually, you only want ____block |
Sensory |
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You accomplish a sensory only block by: |
Decreasing concentration of LA |
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_____ are less sensitive than sensory fibers |
Motor fibers |
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Clinically, _______ fibers get blocked first, although this is not what we want |
Autonomic |
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To achieve surgical anesthesia and motor block, ______ of high concentration of LA are needed |
Large vol |
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_______ block will occur even with low concentrations of LA |
Sympathetic |
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Sequence of clinical anesthesia, #1 |
Peripheral vasodilation |
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Sequence of clinical anesthesia, #2 |
Loss of pain and temp sensation |
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Sequence of clinical anesthesia, #3 |
Loss of touch and pressure sensation |
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Sequence of clinical anesthesia, #4 |
Motor weakness and paralysis |
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Chief determinants of block density |
Lipid solubilit and concentration of LA |
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______ agents are more potent and more readily penetrate lipid membranes |
Highly lipid soluble |
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_____ are able to occupy more receptors and provide a more dense block |
Higher drug concentrations |
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Speed of onset is influenced by |
pKa and concentration |
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The closer the pKa of LA is to the physiologic pH, the more _______ |
Uncharged base form |
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The more uncharged base form, the easier the____ |
Passage thru lipid membrate; hense faster onset |
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2-cholorprocaine should be a slow onset b/c its pKa is |
9 |
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2-cholorprocaine has a low ____ allowing higher concentrations to be given |
Toxcicity |
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2-cholorprocatin has a rapid onset d/t the ______ of drug administered |
Sheer mass |
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DOA is determined by |
Protein binding |
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LA with _____ for receptor protein stay bound for longer time and block Na channel for longer time |
High affinity |
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Dermatomes are cutaneous areas corresponding to individual: |
SC segments |
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The magnitude of the epidural block on the CV system is attributed to the |
Level/degree of sympathetic block |
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Blockade of the _____ --> peripheral vasodilation of the resistance and capacitance vessels |
Efferent sympathetic chain; L1-T4 |
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Elock extending above _____ will include the cardiac accelerator fibers |
T4 |
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Blockade of T4-1 will cause |
Decrease in HR and contractility |
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Blocks extending to T10 are usually well |
Compensated |
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Blocks to T10 |
Increase vasomotor tone in UE |
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Blocks to T10 |
Increase cardiac accelerator activity |
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Blocks to T10 |
Increase catechol secretion |
