Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
25 Cards in this Set
- Front
- Back
Explain Uncomplicated Vs Complicated UTI's
|
Uncomplicated are typically in women only, cystitis or pyelonepritis, anatomically and functionally normal, resolves w/ normal treatment w/o long term renal disfunction even if recurrent.
Complicated would be strx or fx abnormal, antibiotic resistant, my require longer therapy or surgery, and may effect long term renal fx. |
|
A clinical syndrome, due to a UTI that has severe infection or systemic manifestations.
|
Urosepsis
|
|
Are UTI's more common in male or female neonates?
Does circumcision increase or decrease the likelihood of a UTI? In kids and adults UTI's are more common in males or females? |
Male
Decrease Females |
|
Which of the following is not a risk factor for UTI's?
Prior UTI/Family Hx 2 week of menstrual cycle Blood group nonsecretor (SGG and DSGG) Vesicoureteral reflux #&Frequency of sexual partners Spermicide Oral contraceptives Diaphram Voiding/Hygiene practices |
Voiding/Hygiene practices
|
|
Who are the typical culprits of a UTI?
|
Gram Negatives Uropathogens such as:
Enterobacteriaceae (E.coli, Klebsiella, Enterobacter and Proteus) Pseudomonas |
|
Out of the following, which one is known to have a propensity to form kidney stones, and 'splits urea'?
Enterobacteriaceae (E.coli, Klebsiella, Enterobacter and Proteus) Pseudomnas |
Proteus
|
|
Stap saprophyticus is the minor culprit in UTI in:
|
Young women
|
|
Enterococci can cause:
|
complicated UTI's
|
|
What are some key virulence factors in UTI's?
|
P fimbriae - attach
Type 1 fimbriae - are indirectly problematic because the trigger exfoliation, binding and the inflammatory response. |
|
Explain pathogenicity-associated islands
|
virulence factors are found together on large segments of DNA and are acquired by horizontal gene transfer.
|
|
What should be determined if lactobacilli, alpha hemoltic streptococci and anaerobes in urine?
|
Nothing really, they are typically considered to be contaminants unless sign of vaginal fistula is present.
|
|
Cystitis or Pyelonephritis
Dysuria and suprapubic pressure |
Cystitis
|
|
Cystitis or Pyelonephritis
Fever, GI symptoms, costovertebral or flank pain. |
Pyelonephritis
|
|
What can be a sign of sepsis, or due to an obstructed urinary catheter?
|
Decreased urinary output
|
|
Presumtive diagnosis:
Definative diagnosis: |
Symptoms
Pyuria (of leukocyte esterase) Bacteriuria (or gram stain or nitrite) |
|
Positive culture there should be at least how many of the same organism?
A negative culture usually means? |
100,000 cfu/mL
Typically an STD |
|
Treatment
Simple cystitis |
Trimeth/Sulf
Trimeth Fluoroquinolone for three days |
|
Treatment
Simple cystitis in woman over age 40 or diabetic |
Trimeth/Sulf
Fluoroquinolone For 7 days |
|
Treatment
Uncomplicated Pyelonepritis |
Trimeth/Sulf
Fluoroquinolone or 3rd gen cephalosporin |
|
Complicated UTI treatment?
|
Treat for 4-6 weeks
|
|
In Complicated UTI's:
Therapy should be guided by ____ ______, antibiotic course should be 4-6 weeks, oral therapy is usually ________, and you should correct any abnormalities. |
In Complicated UTI's:
Therapy should be guided by urine culture, antibiotic course should be 4-6 weeks, oral therapy is usually adequate, and you should correct any abnormalities. |
|
Patients with a history or clinical findings of renal stones should have:
|
intravenous pyelogram or computer tomography (stone protocol)
|
|
Definition of asymptomatic bacteriuria,
In women In men In catheterized |
In women: 2 consecutive w/ 100,000 cfu/mL
In men: 1 clean catch and 100,000 cfu/mL In catheterized: 1 urine specimen w/ 100 cfu/mL |
|
Only two groups shoud be screened and treated for asymptomatic bacterimia. Who are they?
|
Pregnant and pre-urologic procedures
|
|
Why should you treat asymptomatic bacteriuria in pregnant women and before urologic procedures?
|
Reduce risk of pyelonephritis in mom and prematurity in newborn, and decrease risk of post-operative infections.
|