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25 Cards in this Set

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Explain Uncomplicated Vs Complicated UTI's
Uncomplicated are typically in women only, cystitis or pyelonepritis, anatomically and functionally normal, resolves w/ normal treatment w/o long term renal disfunction even if recurrent.
Complicated would be strx or fx abnormal, antibiotic resistant, my require longer therapy or surgery, and may effect long term renal fx.
A clinical syndrome, due to a UTI that has severe infection or systemic manifestations.
Urosepsis
Are UTI's more common in male or female neonates?
Does circumcision increase or decrease the likelihood of a UTI?
In kids and adults UTI's are more common in males or females?
Male
Decrease
Females
Which of the following is not a risk factor for UTI's?
Prior UTI/Family Hx
2 week of menstrual cycle
Blood group nonsecretor (SGG and DSGG)
Vesicoureteral reflux
#&Frequency of sexual partners
Spermicide
Oral contraceptives
Diaphram
Voiding/Hygiene practices
Voiding/Hygiene practices
Who are the typical culprits of a UTI?
Gram Negatives Uropathogens such as:
Enterobacteriaceae (E.coli, Klebsiella, Enterobacter and Proteus)
Pseudomonas
Out of the following, which one is known to have a propensity to form kidney stones, and 'splits urea'?
Enterobacteriaceae (E.coli, Klebsiella, Enterobacter and Proteus)
Pseudomnas
Proteus
Stap saprophyticus is the minor culprit in UTI in:
Young women
Enterococci can cause:
complicated UTI's
What are some key virulence factors in UTI's?
P fimbriae - attach
Type 1 fimbriae - are indirectly problematic because the trigger exfoliation, binding and the inflammatory response.
Explain pathogenicity-associated islands
virulence factors are found together on large segments of DNA and are acquired by horizontal gene transfer.
What should be determined if lactobacilli, alpha hemoltic streptococci and anaerobes in urine?
Nothing really, they are typically considered to be contaminants unless sign of vaginal fistula is present.
Cystitis or Pyelonephritis
Dysuria and suprapubic pressure
Cystitis
Cystitis or Pyelonephritis
Fever, GI symptoms, costovertebral or flank pain.
Pyelonephritis
What can be a sign of sepsis, or due to an obstructed urinary catheter?
Decreased urinary output
Presumtive diagnosis:
Definative diagnosis:
Symptoms

Pyuria (of leukocyte esterase)
Bacteriuria (or gram stain or nitrite)
Positive culture there should be at least how many of the same organism?
A negative culture usually means?
100,000 cfu/mL

Typically an STD
Treatment
Simple cystitis
Trimeth/Sulf
Trimeth
Fluoroquinolone

for three days
Treatment
Simple cystitis in woman over age 40 or diabetic
Trimeth/Sulf
Fluoroquinolone

For 7 days
Treatment
Uncomplicated Pyelonepritis
Trimeth/Sulf
Fluoroquinolone
or 3rd gen cephalosporin
Complicated UTI treatment?
Treat for 4-6 weeks
In Complicated UTI's:
Therapy should be guided by ____ ______, antibiotic course should be 4-6 weeks, oral therapy is usually ________, and you should correct any abnormalities.
In Complicated UTI's:
Therapy should be guided by urine culture, antibiotic course should be 4-6 weeks, oral therapy is usually adequate, and you should correct any abnormalities.
Patients with a history or clinical findings of renal stones should have:
intravenous pyelogram or computer tomography (stone protocol)
Definition of asymptomatic bacteriuria,
In women
In men
In catheterized
In women: 2 consecutive w/ 100,000 cfu/mL
In men: 1 clean catch and 100,000 cfu/mL
In catheterized: 1 urine specimen w/ 100 cfu/mL
Only two groups shoud be screened and treated for asymptomatic bacterimia. Who are they?
Pregnant and pre-urologic procedures
Why should you treat asymptomatic bacteriuria in pregnant women and before urologic procedures?
Reduce risk of pyelonephritis in mom and prematurity in newborn, and decrease risk of post-operative infections.