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20 Cards in this Set

  • Front
  • Back

Celestone soluspan

Corticosteroid


Phosphate solution for short acting


Acetate for long acting (cloudy)



Decadron

Dexamethasone phosphate


Phosphate Glucocorticoid


Long acting

Kenalog

Triamcinalone acetonide


Acetate glucocorticoid


Intermediate acting

Methylprednisone

Oral Corticosteroid
Contraindicated in: GI disease
May cause necrosis of hip
Interactions: Insulin, antihypertensives, digoxin, aspirin, oral anticoagulants, cyclosporine, vaccines

Complications: glaucoma, weight gain (moon face), diabetes, cataracts

COX 1 and COX 2

COX 1: housekeeping enzymes


COX 2: responsible for inflammation

Diclofenac

COX 2 selective NSAID


Better than others for GI disease (and renal disease/asthma)

Naproxen

Non-selective NSAID


Aleve


Can be used in children (so can ibuprofen)


Also: Naproxen sodium - but also watch for hypertension (extra sodium)

Oxaprozin

Nonselective NSAID


Interacts with H2 receptor antagonists

Nabumetone

Non-selective NSAID


Only non-acidic NSAID, but still causes ulcers (from prostaglandin inhibition)

Sulindac (Clinoril)

Non-selective NSAID
No Renal effects
Causes hypersensitivity - erythema multiforme and SJS

Indomethacin (Indocin)

Non-selective NSAID


Used in acute gouty attacks


Very potent


Do not use in elderly - causes confusion


ADR: GI, thrombocytopenia, agranulocytosis

Tolmetin (tolectin)

Non-selective NSAIDs
Used in children

Fenoprofen (Nalfon)

Similar to ibuprofen


Onset of action: 15-30 minutes

Meloxicam (Mobic)

Less COX 1 activity than many NSAIDs


Used a lot today

Diclofenac

Commonly used, NSAID with less COX 1 activity


Good for asthmatics, GI issues

Misoprostol (Cytotec)

Prostaglandin analogue.


Pregnancy category X


Voltaren/Misoprostol (Arthrotec)

Celecoxib (Celebrex)

Selective COX 2 inhibitor


Can cause cardiovascular issues


Do not use in those with sulfa allergy


Interactions: lithium and diflucan (fluconazole)

Thromboxane is....

Formed by COX 1


Vasoconstrictor


Platelet Aggregator

Prostacyclin is...

Formed by COX 2


Vasodilator


Inhibits platelet aggregation

Colchicine

Gout treatment NSAID


C.I.: renal/hepatic disease, GI, cardiac disease


Dosing: 1.2 mg start of attack, .6 mg 1 hour later