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32 Cards in this Set
- Front
- Back
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Carboxypenicillins (carbenicillin, ticaricillin) |
Can cause hypokalemia and hypernatremia |
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Augmentin (amoxicillin/clavulanic acid) |
Diarrhea and cholestatic hepatitis |
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Cephalosporins Safe for penicillin allergy |
cefdinir and cefuroxime |
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Carbapenems (imipenem, ertapenem, meropenem) |
Contraindicated in penicillin-allergy |
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Aztreonam is good/bad for renal toxicity |
GOOD |
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Aminoglycoside (gentamycin, tobramycin, amikacin) ADRs |
Irreversible ototoxicity Reversible nephrotoxicity Hypokalemia and hypomagnesia Do not use in diabetes or myasthenia gravis |
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Vancomycin ADRs |
Reversible ototoxicity and nephrotoxicicty Vestibular problems Thrombophlebitis Red man syndrome |
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Ortivancin Interaction |
Warfarin (prolongs aPTT and PT/INR) |
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Tetracycline (Doxycycline, minocycline, methacycline, tetracycline) ADRs |
Doxy- photo-onycholysis Mino- hyperpigmentation GI complaints Acute pancreatitis Erosive esophagitis Pregnancy/woman problems: Teeth staining, bone issues |
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Tetracycline Interactions |
Digoxin Accutane - pseudotumor cerebri risk |
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Macrolides (Azithromycin, clarithromycin, erythromycin) Interactions |
Increases digoxin, HMG CoA reductase inhibitors, Coumadin |
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Chloramphenicol ADR |
Gray baby syndrome Severe bone marrow toxicity Aplastic anemia |
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Bactrim Interactions |
Sulfonylureas - hypoglycemia risk Enhances marrow suppression with methotrexate Increases coumadin |
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Bactrim ADR |
Pancreatitis, hyperkalemia |
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Metronidazole (Flagyl) ADRs |
Peripheral neuropathy
Disulfram RXN Dark urine |
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Metronidazole (Flagyl) interactions |
Coumadin |
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Ciprofloxacin ADR |
Tendonitis and tendon rupture |
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Quinolones (-floxacin) ADRs |
Joint cartilage damage in <18 year olds and pregnant women |
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Rifampin interactions |
Increases hepatic clearance, decreases half lives of many drugs |
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Linezolid (Zyvox) ADR |
Myelosuppression ,N/V, peripheral and optic neuropathy Monitor CBC |
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Linezolid (Zyvox) Interaction |
SSRIs and MAOIs - serotonin syndrome |
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Tedizolid (Sivextro) ADRs |
N/V/D, headache |
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Daptomycin (Cubicin) Interactions |
Tobramycin |
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Daptomycin ADRs |
Myopathy - potentiated by statins Eosinophilic pneumonia |
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Tigecycline (Tygacil) ADR |
N/V Permenent discoloration of teeth |
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Terbinafine (Lamisil) Interactions |
TAMOXIFEN |
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Methylprednisone Interactions |
Antihypertensives Insulin Digoxin Cyclosporine Aspirin Vaccines Anticoagulants |
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Suldinac (Clinoril) ADR |
No renal effects Hypersensitivity - SJS and erythema multiforme |
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NSAID drug interactions |
Diuretics Propanolol Methotrexate Lithium Aspirin Warfarin Sulfonamides |
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Misoprostol (Cytotec; prostaglandin analogue) |
Spontaneous Abortion |
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Celecoxib (Celebrex) |
Cardiovascular issues - can cause MI due to thromboxane and prostacycline balance |
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Tapentadol (Nucynta) Interactions |
SSRI - Serotonin syn |
