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15 Cards in this Set

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Interorganismal chemical communication.

Chemical communication occurring outside the body. Pheromones(individuals of same species) and allelochemical (diff species).


Short range -alarm, recognition, courtship


Long range- Territory markers, sex attractants.

Intercellular chemical communication

Chemical communication that occurs better cells.


Short range- neurotransmitters


Long range- hormones

Intracellular chemical communication

Chemical communication within a cell. Intracellular messangers relay information from cell surface receptors to activate appropriate cellular responses.

Intercellular signalling- cells that release messanger chemicals that can affect:

Juxtacrine- Adjacent cells by direct contact.


Autocrine-Themselves


Paracrine - Nearby cells


Endocrine and Neuroendocrine- distant cells.


Pheromonal- other organisms


What is a ligand

A molecule that binds to another (usually larger) receptor molecule. Ligand classes : neurotransmitters, cytokinesis, growth factors, death factors, hormones.

Cytokines

Peptide, proteins or glycoproteins, they are intercellular signalling- molecules that may operate by Juxtacrine, Autocrine, paracrine or endocrine signalling. Can be produced by almost any cell type.

Growth factors.

A class of cytokines that specifically stimulate growth, proliferation or cellular differentiation.

Death factors

A class of cytokines that specifically stimulate programmed cell death (apoptosis).

Hormones

Chemically varibale amines, steroids, peptides that act by endocrine signalling but are produces from specific glands (eg insulin).

Hydrophilic chemicals signalling method.

Water soluble and cannot pass directly through lipid cell membranes (they must exert their effect via cell surfaces receptors to activate intracellular 2nd messanger chemicals).

Hydrophobic chemical signalling method

Hydrophobic chemicals are lipid soluble and therefore diffuse through lipid cell mebranes to bind directly to intracellular receptors.

Fast synaptic transmitters

Eg. Acetlycholine


Fast transmitters alter membrane permeabilities to ions -iontrooic effect.

Slow synaptic transmitters

Eg. Noradrenaline, dopamine


Slow transmitters stimulate the production of intracellular Messengers that affect the metabolism of the cell- metabotropic effects.

Hormonal effects depend on

Age, sex, season

Hormonal effects can be :



Organisational -occur early in life (usually permanent).Activational- occur in adults (effect only persists while the hormone is present).