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16 Cards in this Set
- Front
- Back
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aminoglycosides |
concentration-dependent prolonged PAE Cmax/MIC > 10-12 AUC/MIC |
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fluoroquinolones |
concentration-dependent prolonged PAE Cmax/MIC AUC/MIC 30-50 (+), 125(-) |
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beta-lactam |
time-dependent minimal PAE T>MIC 40-50% |
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macrolide |
time-dependent minimal PAE T>MIC |
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linezolid |
time-dependent minimal PAE T>MIC |
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azithromycin |
time-dependent moderate PAE AUC/MIC |
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clindamycin |
time-dependent moderate PAE AUC/MIC |
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tetracyclines |
time-dependent moderate PAE AUC/MIC |
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vancomycin |
time-dependent AUC/MIC >345 |
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vanco dosing, pre-HD levels |
<10 --> 15mg/kg IV post-HD 10-20 --> 1g IV post-HD 20-25 --> 500 mg IV post-HD >25 --> hold dose |
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vanco dosing, post-HD levels |
<10 --> 15kg/mg x 1 10-15 --> 5-10mg/kg x 1 15-20 --> hold dose |
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cefazolin or cephalothin |
PD 15 mg/kg intermittent LD 500; MD 125 |
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ceftazidime |
pd 1000-1500 mg intermittent LD 500; MD 125 |
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gentamicin or tobramycin |
pd 0.6 mg/kg LD 8; MD 4 |
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vancomycin pd |
pd 15-30 mg/kg q5-7d LD 1000; MD 25 |
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pd dosing considerations |
if renal fx >100 ml/d then inc dose by 25% and do not give aminoglycosides |
