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33 Cards in this Set
- Front
- Back
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who has pigmented lesions
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darker colored skin
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where are pigmented lesions mostly found?
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Most often found on attached gingiva
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what are DD for pigmented lesions
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amalgam tattoo and junctional nevus
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who gets smoker's melanosis?
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females who are on birth control that has been smoking for 3 years
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what are visual cues for smoking melanosis
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Visual cues:
Covered with intact mucosa Anterior gingiva of mandible for cigarette smokers Buccal mucosa Palate for pipe smoking Diffuse irregular brown patches |
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what is ephelis
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it is a freckle
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what is oral melanotic macule
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pigment made by basal layer in oral cavity
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what is labial melanotic macule
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pigment made by basal layer in lips
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where do you mostly get ephelis? where specifically on body
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sun exposed area. lips 85%
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where is oral melanotic macule found?
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buccal mucosa, palate, gingiva
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who mostly gets melanotic macule?
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female
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does melanotic macule get bigger after dx?
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no
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does melanotic macule dependent on sun exposure
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no
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what are tx for melanotic macule and ephelis? is it in danger of becoming a melanoma?
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biopsy/excision to see if melanoma. esp if it gets bigger. but it is not in danger of becoming a melanoma
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what is DD for melanotic macule and ephelis? and what is their clincial significance
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Differential diagnosis:
Amalgam tattoo Early malignant melanoma Melanocytic nevus Clinical significance: Peutz-Jeghers syndrome Addison’s disease |
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what does pigmented cellular nevus look like/description
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May be brown or non-pigmented, smooth or elevated
Does not blanch with pressure Can be smooth, flat or elevated Usually <6mm in diameter |
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where will you most likely find pigmented cellular nevus? *
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palatal
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pigmented cellular nevus stay forever
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may regress later in life
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what is The most common of all human “tumors” but uncommon in the oral cavity
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pigmented cellular nevus
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where are pigmented cellular nevus from
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neural crest
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what are classification of pigmented cellular nevus
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Classification is based on location and morphology:
Junctional Nevus Compound Nevus Intradermal Nevus |
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what are variations of nevi
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Other variations:
Blue Nevus Halo nevus Spitz nevus – benign juvenile melanoma Congenital melanotic nevus |
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define junctional nevus, compound nevus, and intradermal nevus
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Junctional nevus:
Cells are located at the junction of epithelium and connective tissue Any activity at the junction can easily become malignant melanoma Compound nevus: Cells are found along the junctional area and within the underlying connective tissue Intradermal nevus- Known as intramucosal nevus when found intraorally Cells are found only within the connective tissue The most common intraoral nevi |
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The most common intraoral nevi
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intradermal nevus
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2nd most common intraoral nevi. where commonly found
who gets it histo |
blue nevus
hard palate female spindles cells (think stars in blue sky) |
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tx for pigmented cellular lesions
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Treatment
Excisional biopsy Some lesions lose their color with age and may undergo regression |
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DD for pigmented cellular nevus
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Differential Diagnosis
Amalgam tattoo Melanotic macule Early melanoma |
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3rd most common cancer of the skin
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malignant melanoma
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where mostly for malig melanoma? by what
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25% occur in the head and neck area
Sunlight is strongly implicated |
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Ulceration is common in malig melanoma
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yes
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risk factors for malig melanoma
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Risk Factors
Fair complexion Light hair Tendency to sunburn History of blistering History of dysplastic or congenital nevus History of a relative with malignant melanoma |
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prog for oral melanoma
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Prognosis for Oral melanoma
45% for 5 years 28% for 10 years |
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Growth occurs in two phases
for malig melanoma |
1. Radial-growth Phase – cells spread laterally
but stay confined to the surface epithelium 2. Vertical-growth Phase – cells invade and populate the connective tissue. |
