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26 Cards in this Set
- Front
- Back
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What is another name for physiologic (racial) pigmentation?
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Melanoplakia
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Name the most common location for physiologic (racial) pigmentation/melanoplakia.
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Attached gingiva
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What causes physiologic (racial) pigmentation/melanoplakia?
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Increased ACTIVITY (not number) of melanocytes
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Name two risk factors (besides smoking) for Smoker's Melanosis.
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1 Female 2 Females on the Pill
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Name the three most common areas to see Smoker's Melanosis.
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1 Mandibular anterior (gingiva) 2 Buccal mucosa 3 Palate
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Is Smoker's Melanosis premalignant?
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No, not alone
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Does Smoker's Melanosis go away after quitting smoking?
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Yes, probably
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T/F: Oral Melanotic Macules are due to sun-exposure.
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False, freckles are
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What disease histologically features an increase in melanin granules, which is confined to the basal cell layer?
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Oral melanotic macule
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What is the most common of all human 'tumors'?
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Pigmented Cellular Nevus/ Acquired melanocytic nevus/Mole
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Name 2 synonyms for a mole.
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1 Pigmented Cellular Nevus 2 Acquired melanocytic nevus
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What's the difference between a mole and a freckle (ephelis)?
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A mole does NOT depend on sun exposure; freckles do.
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What do nevus cells look like (4)?
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1 Large 2 Oval 3 Epithelioid 4 Arranged in clumps
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What type of mole do all moles start out as?
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Junctional nevus
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What variant of mole is the second most common intraoral nevus?
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Blue
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Malignant melanoma is the (#) most common skin cancer. ____% of skin melanomas occur in the head/neck area. (Chronic/acute) sun damage is more important when it comes to malignant melanoma. The lifetime risk for a __(ethnicity)__ to get malignant melanoma is 1 in _____.
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3rd most common. 25% in head and neck. Acute is worse. Caucasians 1:100 will get them.
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What is the most common type of Malignant melanoma?
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Superficial spreading melanoma
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What type of Malignant melanoma is multicolored and flat?
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Superficial spreading melanoma
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1/3 of this type of Malignant melanoma are in the head and neck area.
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Nodular melanoma
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What type of Malignant melanoma is elevated, and sometimes has no pigmentation?
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Nodular melanoma
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What type of Malignant melanoma is melanoma in situ?
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Lentigo maligna melanoma
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What is the most common type of oral Malignant melanoma?
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Acral lentiginous melanoma
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Name the two most common sites for oral Malignant melanoma.
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1 Maxillary anterior mucosa 2 Hard palate
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Most oral Malignant melanomas are (primary/metastatic) and have (good/bad) prognosis.
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Metastatic, bad
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How does Addison's disease manifest in the skin/mucous membranes?
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Bronzing
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What are two clinical features of Peutz-Jeghers Syndrome?
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1 Oral freckles (melanotic macules) 2 Intestinal polyposis
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