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13 Cards in this Set

  • Front
  • Back
What is the main characteristic of obstructive lung disease?
Airflow limitation, not fully reversible and progressive and is associated with an abnormal inflammatory response to noxious stimuli(particles or gases)
What are the major characteristics of restrictive lung disease?
Inflammation and fibrosis of lung parenchyma resulting in abnormalities in gas exchange at rest or during exercise.
What happens to FEV1 and FVC in restrictive disease processes?
Both FEV1 and FVC are reduced(FEV1/FVC is normal or increased).
What happens to FEV1 and FVC in obstructive disease processes?
FEV1 is reduced more than FVC(FEV1/FVC is decreased).
What types of cells line the alveoli?
Two types.
Type 1 pneumocytes(90%) primary lining cells
Type 2 pneumocytes(10%), granular cells
What is respiratory dead space?
Space in the conducting zone of the airways where no gas exchange occurs.
What types of dead space exist?
1. Anatomic dead space(conducting airways)
2. Alveolar dead space (alveoli with no blood flow)
How can you approximate the volume of anatomic dead space/
Dead space in milliliter=body weight in pounds.
What are the functions of anatomic dead space?
Conditions air(is warmed and saturated with water vapor)
Removal of foriegn material.
What is alveolar ventilation?
The amount of air reaching the alveoli per minute.
How does dead space affect alveolar ventilation?
Some inspired gas is trapped in the dead space making alveolar ventilation less than the respiratory minute volume.
How does shallow versus deep breathing affect alveolar ventilation?
Rapid shallow breathing produces much less alveolar ventilation.
How can dead space V(D) be calculated?
P(e)CO2 X V(t)= P(a)CO2(V(t)-V(d) + P(i)CO2 X V(d)