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55 Cards in this Set
- Front
- Back
General Properties of the ANS
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Motor nervous system that controls glands, cardiac and smooth muscle
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ANS regulates ______ processes that maintain homeostasis
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unconscious
EX: blood pressure, body temperature, respiratory airflow |
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ANS carries out its actions ______ our intent
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without (automatically)
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ANS regulated by which parts of the brain and can change rapidly and with great intensity
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hypothalamus, pons and medulla
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Unconscious, automatic responses to stimulation of glands, cardiac or smooth muscle
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Visceral Reflexes
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Receptors detect ________ -- stretch, blood chemicals, body temperature, etc.
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internal stimuli
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_____ reflexes (urination, defecation, penile erection)
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Autonomic
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______ neurons carry motor signals to the effectors
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Efferent
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ANS ______ effector activity rather than causing it
--high blood pressure activates a visceral baroreflex |
modifies
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Visceral Reflex to High BP...
{{Separate reflex arc for low BP exists}} |
**High BP detected by arterial stretch receptors, signal transmitted to CNS, efferent signals travel to the heart, heart slows reducing BP
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-1 neuron to target organ
-acetylcholine (NT) -ACh + nicotinic cholinergic -Excitatory only (Effects) |
Somatic NS
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-2 neuron to target organ
-acetylcholine / norepinephrine - ACh+ muscarinic cholinergic or NE+alpha or beta adrenergic -Excitatory or inhibitory |
Autonomic NS
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ANS = 2 neurons span the distance from CNS to effectors
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1.presynaptic neuron cell body in CNS--brain or spinal
2. postsynaptic neuron cell body in peripheral ganglion |
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_____ division prepares body for physical activity
**increases heart rate, BP, airflow, blood glucose levels, |
Sympathetic
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______ division has calming affect on many body functions & assists in bodily maintenance
**digestion and waste elimination |
Parasympathetic
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______ is the normal rate of activity that represents the balance of the two systems
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Autonomic tone
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Effects of each divisions of the ANS depend upon ...
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neurotransmitters released and the receptors of the target organ
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Origin of Parasympathetic Pathways
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**Sacral region of spinal cord
**Brain stem (cranial nerves) |
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?? nerve narrows pupil & focuses lens
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Oculomotor nerve (III)
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?? nerve regulates secretion of tear, lacrimal & 2 salivary glands
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Facial nerve (VII)
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?? nerve regulates parotid salivary gland
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Glossopharyngeal (IX)
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?? nerve regulates muscles and glands of the viscera as far inferiorly as the proximal half of colon
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Vagus nerve (X)
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Origin of Sympathetic Pathways
Exit spinal cord in two regions |
thoracic
lumbar |
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Cholinergic Receptors for ACh
Acetylcholine binds to 2 classes of receptors.. |
nicotinic receptors
muscarinic receptors |
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**occur on all ANS postganglionic neurons, in the adrenal medulla, and at NMJ (skeletal muscle)
**excitatory when ACh binding occurs |
nicotinic receptors
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**occur on all gland, smooth muscle & cardiac muscle cells that receives cholinergic innervation
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muscarinic receptors
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**either excitatory or inhibitory when ACh binding occurs due to subclasses of muscarinic receptors
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muscarinic receptors
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muscarinic receptors
Blocked by ______ |
atropine
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Nor-epinephrine binds to 2 classes of receptors
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**alpha adrenergic receptors
**beta adrenergic receptors |
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alpha 1 + NE -->
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Smooth muscle contraction
&/or increase secretion of a gland |
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alpha 2 + NE -->
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Smooth muscle relaxation
&/or decrease secretion of a gland |
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beta 1 + NE/Epi -->
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Increase cardiac muscle concentration
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beta 2 + NE/Epi -->
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Smooth muscle relaxation
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Beta 1 ==> ??
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cardiac muscle & kidney
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Beta 2 ==> ??
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smooth muscle of airways & cardiac vasculature (coronary arteries)
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- ACh released
-Nicotinic cholinergic (receptor) -NE (usually)/ACh (sweat gl.) - α or ß adrenergic or muscarinic cholinergic |
Sympathetic
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- ACh released
-Nicotinic cholinergic (receptor) -ACh - muscarinic cholinergic |
Parasympathetic
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_______ are also known as cholinergic agonists or parasympathomimetics
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Cholinergic Agents
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Cholinergic Agents mimic the effect of _____
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ACh
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Cholinergic Agents activate _____ nervous system
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parasympathetic
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Cholinergic Agents result in _______
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SLUDGE (salivation, urinary incontinence, diarrhea, GI cramps, emesis)
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NOTE: Cholinergic Agents also pupil constriction, decreased intraocular pressure, increases salivation
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and sweating, decreased heart rate, vasodialtion, respiratory airway constriction
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___________ suppress activity
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Parasympatholytics
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also known as adrenergic agonists or sympathomimetics
ex. phenylephrine |
Adrenergic Agents
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Adrenergic Agents mimic the effect of _____
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NE or Epi
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NOTE: Alpha agonists bring :
-vasoconstriction and increase BP (α1) relaxation of GI smooth muscle |
-contraction of uterus and
bladder, male ejaculation, decrease insulin release, pupil dilation |
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Paired glands sit on superior pole of each kidney
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Adrenal Glands
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Adrenal Glands
Cortex secrete??? |
secretes steroid hormone
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Adrenal Glands-- Medulla ??
{{catecholamines (85% epi & 15% norepi)}} |
modified sympathetic ganglion that secretes NT (hormones) into blood and not onto other neurons
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Management of clinical depression- which drugs
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Prozac (SSRI)
MAO inhibitors |
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which drug blocks reuptake of serotonin to prolong its mood-elevating effect
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Prozac (SSRI)
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which drug interfere with breakdown of monoamine neurotransmitters
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MAO inhibitors
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______ competes with adenosine (inhibitory causing sleepiness) by binding to its receptors
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Caffeine
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Propanolol blocks the Beta 1-adrenergic receptors located in cardiac muscle tissue. This action would serve to:
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B. decrease heart rate
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When epinephrine binds to Beta 2-adrenergic receptors found in the smooth muscle of the airways, the result is ______.
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B. relaxation of the smooth muscle of the airways
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