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55 Cards in this Set

  • Front
  • Back
General Properties of the ANS
Motor nervous system that controls glands, cardiac and smooth muscle
ANS regulates ______ processes that maintain homeostasis
unconscious
EX: blood pressure, body temperature, respiratory airflow
ANS carries out its actions ______ our intent
without (automatically)
ANS regulated by which parts of the brain and can change rapidly and with great intensity
hypothalamus, pons and medulla
Unconscious, automatic responses to stimulation of glands, cardiac or smooth muscle
Visceral Reflexes
Receptors detect ________ -- stretch, blood chemicals, body temperature, etc.
internal stimuli
_____ reflexes (urination, defecation, penile erection)
Autonomic
______ neurons carry motor signals to the effectors
Efferent
ANS ______ effector activity rather than causing it
--high blood pressure activates a visceral baroreflex
modifies
Visceral Reflex to High BP...

{{Separate reflex arc for low BP exists}}
**High BP detected by arterial stretch receptors, signal transmitted to CNS, efferent signals travel to the heart, heart slows reducing BP
-1 neuron to target organ
-acetylcholine (NT)
-ACh + nicotinic cholinergic
-Excitatory only (Effects)
Somatic NS
-2 neuron to target organ
-acetylcholine / norepinephrine
- ACh+ muscarinic cholinergic or NE+alpha or beta adrenergic
-Excitatory or inhibitory
Autonomic NS
ANS = 2 neurons span the distance from CNS to effectors
1.presynaptic neuron cell body in CNS--brain or spinal
2. postsynaptic neuron cell body in peripheral ganglion
_____ division prepares body for physical activity
**increases heart rate, BP, airflow, blood glucose levels,
Sympathetic
______ division has calming affect on many body functions & assists in bodily maintenance
**digestion and waste elimination
Parasympathetic
______ is the normal rate of activity that represents the balance of the two systems
Autonomic tone
Effects of each divisions of the ANS depend upon ...
neurotransmitters released and the receptors of the target organ
Origin of Parasympathetic Pathways
**Sacral region of spinal cord
**Brain stem (cranial nerves)
?? nerve narrows pupil & focuses lens
Oculomotor nerve (III)
?? nerve regulates secretion of tear, lacrimal & 2 salivary glands
Facial nerve (VII)
?? nerve regulates parotid salivary gland
Glossopharyngeal (IX)
?? nerve regulates muscles and glands of the viscera as far inferiorly as the proximal half of colon
Vagus nerve (X)
Origin of Sympathetic Pathways
Exit spinal cord in two regions
thoracic
lumbar
Cholinergic Receptors for ACh

Acetylcholine binds to 2 classes of receptors..
nicotinic receptors

muscarinic receptors
**occur on all ANS postganglionic neurons, in the adrenal medulla, and at NMJ (skeletal muscle)
**excitatory when ACh binding occurs
nicotinic receptors
**occur on all gland, smooth muscle & cardiac muscle cells that receives cholinergic innervation
muscarinic receptors
**either excitatory or inhibitory when ACh binding occurs due to subclasses of muscarinic receptors
muscarinic receptors
muscarinic receptors
Blocked by ______
atropine
Nor-epinephrine binds to 2 classes of receptors
**alpha adrenergic receptors
**beta adrenergic receptors
alpha 1 + NE -->
Smooth muscle contraction
&/or
increase secretion of a gland
alpha 2 + NE -->
Smooth muscle relaxation
&/or
decrease secretion of a gland
beta 1 + NE/Epi -->
Increase cardiac muscle concentration
beta 2 + NE/Epi -->
Smooth muscle relaxation
Beta 1 ==> ??
cardiac muscle & kidney
Beta 2 ==> ??
smooth muscle of airways & cardiac vasculature (coronary arteries)
- ACh released
-Nicotinic cholinergic (receptor)
-NE (usually)/ACh (sweat gl.)
- α or ß adrenergic or muscarinic cholinergic
Sympathetic
- ACh released
-Nicotinic cholinergic (receptor)
-ACh
- muscarinic cholinergic
Parasympathetic
_______ are also known as cholinergic agonists or parasympathomimetics
Cholinergic Agents
Cholinergic Agents mimic the effect of _____
ACh
Cholinergic Agents activate _____ nervous system
parasympathetic
Cholinergic Agents result in _______
SLUDGE (salivation, urinary incontinence, diarrhea, GI cramps, emesis)
NOTE: Cholinergic Agents also pupil constriction, decreased intraocular pressure, increases salivation
and sweating, decreased heart rate, vasodialtion, respiratory airway constriction
___________ suppress activity
Parasympatholytics
also known as adrenergic agonists or sympathomimetics
ex. phenylephrine
Adrenergic Agents
Adrenergic Agents mimic the effect of _____
NE or Epi
NOTE: Alpha agonists bring :
-vasoconstriction and
increase BP (α1)
relaxation of GI smooth muscle
-contraction of uterus and
bladder, male ejaculation,
decrease insulin release,
pupil dilation
Paired glands sit on superior pole of each kidney
Adrenal Glands
Adrenal Glands
Cortex secrete???
secretes steroid hormone
Adrenal Glands-- Medulla ??

{{catecholamines (85% epi & 15% norepi)}}
modified sympathetic ganglion that secretes NT (hormones) into blood and not onto other neurons
Management of clinical depression- which drugs
Prozac (SSRI)
MAO inhibitors
which drug blocks reuptake of serotonin to prolong its mood-elevating effect
Prozac (SSRI)
which drug interfere with breakdown of monoamine neurotransmitters
MAO inhibitors
______ competes with adenosine (inhibitory causing sleepiness) by binding to its receptors
Caffeine
Propanolol blocks the Beta 1-adrenergic receptors located in cardiac muscle tissue. This action would serve to:
B. decrease heart rate
When epinephrine binds to Beta 2-adrenergic receptors found in the smooth muscle of the airways, the result is ______.
B. relaxation of the smooth muscle of the airways