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3 Cards in this Set
- Front
- Back
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Hodgkin cycle |
A positive-feed back loop is transiently established at threshold Only lasts 1 ms depolarizing stimulus depolarization VGNCs open net NA+ influx depolarization . . . |
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States of voltage-gated sodium channels (VGNCs) |
1. Closed and capable of opening - requires relatively negative RMP 2. Opening and conducting NA+ ions into cytosol 3. Inactivated: non-conducting can occur at positive voltage |
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Features of action potentials |
1. Carry long distance electrical signals 2. Trigger physiological events 3.Self creating without getting smaller 4. High velocity up to 100m/sec 5. Require RMP be relatively negative (65 MV or move negative) 6. Convey both digital (number of APs) and analogue (amp. and duration) info. 7. Abnormalities in APs are severe or fatal (epilepsy, multiple sclerosis, cardiac arrhythmias, muscle paralysis, myotomia: can't relax) |
