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145 Cards in this Set

  • Front
  • Back
About 2/3 of the water in the body is what?
intracellular
About 1/3 of the water in the body is what?
extracellular
What % of body weight is water?
57%
What makes up 7% of body water?
plasma
What makes up 18% of body water?
lymph
What makes up 12% of body water?
CSF, synovial, ears, eyes, etc.
How much fluid do you take in daily by food and drink?
2100 ml/day
How much fluid do you take in daily by catobolic water?
200 ml/day
The regulation of fluid intake is stimulated by what?
thirst center
The thirst center located where is sensitive in blood osmotic pressure?
thirst center
The thirst center in the hypothalamus stimulates the release of what when osmotic pressure is too high?
ADH
What are in major arteries that detect any drop in BP and alert the thirst center?
pressoreceptors
What stimulates the thirst center?
angiotensin II
With increased BP there is an increase in what?
GFR and urine
With increased BOP, what is released which increases water resorption in DCT and CD?
BOP
With decreased BP, the kidney releases what?
renin
What needs to stay in the blood so BP will stay in increased?
solute
What is the specific heat of copper?
0.092
What is the term for raising one calorie to one gram?
high specific heat
High specific heat has a high ability to maintain what?
body temperature
Is water more or less dense when frozen?
less
At what temperature is water most dense?
3.98 degrees celsius
What happens to water when it becomes less dense?
it floats
What is the term for water having a plus and minus charge?
polarity
Water has a plus and minus charge which makes it what?
efficient solvent
How much energy does it take for water to convert from liquid to gas
539 cal/gram
Why is water a very efficient coolant for the body?
high heat of vaporiztion
How much energy is needed to raise a gram?
1 calorie
What is function of water that converts liquid water into a solid?
high heat of fusion
How much energy does it take to convert liquid water into a solid?
80 cal/gram
What is the term for the function of water moving up tubes by capillary action?
high suface tension
What allows insects to walk on top of water?
high surface tension
What % of oxygen is in plasma?
2%
What are the functions of water?
transport O2, CO2 waste, food
Solvent for chemical reactions
Diluton for acids
Maintain osmotic balance
Hydrostatic movement
What is an example of hydrostatic movement?
peristalsis in the gut
What are the types of electrolytes?
anions and cations
What are some examples of anions?
Cl-, HCO3-, HPO4-2
What are some examples of cations?
Na+, K+, MG+2
Where do electrolytes inonize in?
solution
Electrolytes control osmotic pressure because they are what?
solutes
Where are the major regions of the body where there are electrolytes?
plasma, interstitial fluid, intracellular fluid
What is the content of Na, Cl, protein, and K in plasma?
high Na and Cl, medium protein, low K
What is the content of Na, Cl, protein, and K in plasma?
high Na and Cl, low protein and K
What is the content of Na, Cl, protein, and K in plasma?
high protein and K, low Na and Cl
What is an expression of the number of charges in a solution?
mEq/L
Values of electrolytes are measured in what?
mEq/L
What is the term for MW in milligrams per L?
millimoles
What is the term for # of particles per unit volume?
milliosmoles
What impacts osmotic pressure?
milliosmoles
What is the term for # of charges per unit volume?
milliequivalents
What indicates the charges in a solution?
equivalents
What is the typical value of sodium and potassium in plasma?
Na=140 K=5
What is the typical value of sodium and potassium in interstitial space?
Na=135 K=10
What is the typical value of sodium and potassium in intracellular space?
Na=10 K=130
What means "we like it, so we eat it"?
hedonistic
What % of potassium in filtrate is lost?
15%
Where can you get potassium from?
food and traces of cytoplasm
Increased what causes us to dump potassium?
aldosterone
What is released when serum calcium is too low?
parathormone
What is in bone tissue that extracts calcium from the bone?
osteoclasts
Where is calcium absorbed?
gut and kidney
What causes 25, hydroxycholecelcipherol to be transformed into Vitamin D?
parathormone
What increases the the absorption of calcium from the gut?
Vitamin D
What converts 7-dehydrocholesterol in skin to cholecalcipherol?
UV light
What converts cholecalcipherol to 25, hydroxycholecalapherol?
liver
What converts 23, hydroxycholecalapherol to 1,25 dihydroxycholecelapherol?
PTH
What is the abbreviation of 1,25 dihydroxycholecelapherol?
1,25 (OH)2 D3
Where is calcitonin release from?
thryoid gland
What is released when serum caclium level rises above normal levels?
calcitonin
What is one of the most critical balances in live?
acid base balance
What are compounds that produce hydrogen ions when placed in solution?
acids
What are compounds that accepts hydrogen ions in solution?
bases
What are substances that prevent extreme changes in the number of free hydrogen ions or free Oh- in solution?
buffers
What are the four buffer systems?
bicarbonate, hemoglobin, phosphate, and protein
What is an expression of the H+ concentration in solution?
pH
What is the pH of pure water equal to?
7
What is the whole name of pH?
puissance Hydrogen
As the concentration of H+ increases in solution, what decreases in solution?
OH-
What means that for each change in number the concentration changes ten times?
logarithmic
The pH scale was named by who?
Sorensen
Is the pH of most foods and drugs acidic or basic?
acidic
What factors can cause pH change?
increase or decrease in pH
catabolic acid production
ingestion of acid foods and drugs
pH is balanced at about 7.4
What terms is used when CO2 is discussed during pH?
respiratory acidosis or alkalosis
If you increase CO2 content, what else do you increase?
H+
What terms are used with acid production?
metabolic acidosis or alkalosis
If your pH shifts below 7.35, what is this called?
acidosis
If your pH shifts above 7.45, what is this called?
alkalosis
What can cause acidosis?
hypoventilation, increase in H+, lose bicarbs
What can cause alkalosis?
hyperventilation, H+ loss (vomit), increase bicarbs (antacids)
What can adujust for the change of pH?
compensation and buffers
What prevents drastic changes in pH?
buffers
How do buffers prevent drastic pH change?
add or sponge up H+
What do not completely ionize in solution?
weak acids
What type of buffer adds H+ or OH- to shift toward or away from CO2 and H2O?
carbonic acid/bicarbonate buffer
What happens when acid are added to blood or lymph?
shift away from the H+ and HCO3-
What combines with H+ to become water?
OH-
What happens when OH- is added to a solution?
shifts toward H+ and HCO3-
What buffer system is present in blood and interstitial fluid and has to do with monobasic and dibasic?
phophate buffer system
Is mono or dibasic an H+ donor?
monobasic
Is mono or dibasic an H+ acceptor?
dibasic
What buffers H+ in RBC's?
hemoglobin-oxyhemoglobin buffer
What is a weaker acid, hemoglobin or H2CO3?
hemoglobin
What happens when hemoglobin gives up oxygen and takes on a negative charge?
hemoglobin steals H+ from H2CO3
What works as a buffer because there is a carboxyl at one end and an amine at the other end?
protein buffer system
Kidney excretion helps to maintain what?
pH
What two things can the kidneys do to help maintain pH?
dump H+ and conserve HCO3- or conserve H+ and dump HCO3-
What kidneys compensate for pH change it is called what?
metabolic compensation
What is the increase of H+ content somewhere like in muscle?
dilution
What the lungs compensate for pH change what is this called?
respiratory compensation
Increased PCO2 in blood causes what?
decreased pH
What causes respiratory alkalosis because an increased breathing rate causes more carbon dioxide to be blown ou?
hyperventilation
Can you have acidosis or alkalosis at the same time?
no
When hyperventilation occurs, the PCO2 value is lowered to what?
35 mmHg
What causes respiratory acidosis becasue carbon dioxide is not released from blood?
hypoventilation
When hypoventilation occurs, the PCO2 value is increased to what?
45 mmHg
What is the normal pH?
7.35-7.45
What pH level would cause acidosis?
below 7.35 (7.38)
What pH level would casue alkalosis?
above 7.45 (7.42)
What is the term for inadequate CO2 release from lungs?
respiratory acidosis
What are some examples of respiratory acidosis?
emphysema, polio, obesity, pulmonary edema, kyphoscoliosis
What is the term for a decrease of CO2 in blood?
respiratory alkalosis
What one thing causes respiratory alkalosis?
hyperventilation
What is the term for the HCO3- content is below 24 mEq/L?
metabolic acidosis
What is the normal value for bicarbonate (HCO3-)?
24 mEq/L
What does "rhe" mean"
flow
What can cause metabolic acidosis?
abnormally high acid producing metabolism
bicarbonate loss
renal failure
acid drugs
What is the term for HCO3- is above 24 mEq/L?
metabolic alkalosis
What causes potassium to be placed into the filtrate while sodium is resorbed?
aldosterone
Aldosterone activity causes a loss of what which can push someone into alkalosis?
hydrogen ions
When pH deviates from normal it moves in one of two directions: what are they?
toward acidosis or alkalosis
What is the ratio of H2CO3 to HCO3-?
1:20
If the ratio of H2CO3 and HCO3- is less then 1:20 what does the pH shift to?
acidosis
If the ratio of H2CO3 and HCO3- is more then 1:20 what does the pH shift to?
alkalosis
If the ratio of H2CO3 and HCO3- is 1:1, what is the pH?
6.2
When the pH is 6.2 and there are equal amounts of the reactants is reached what is this called?
pK
What three values do you get when a lipid panel is done?
PaCO2, HCO3-, pH
In normal blood, what is the value of PCO2?
40 mmHg
In normal blood, what is the value of HCO3-?
24 mEq
In normal blood, what is the value of H2CO3?
1.2 mEq
Can you have acidosis and alkalosis at the same time?
no
Can you have both repiratory alkalosis and metabolic alkalosis at the same time and same with acidosis?
yes
A PCO2 level above 40 mmHg (if acting alone) shitfts blood into what?
respiratory acidosis or compensation for metabolic alkalosis
A PCO2 level below 40 mmHg shift blood into what?
respiratory alkalosis or compensation for metabolic acidosis
A HCO3- level above 24 mEq/L shifts blood into what?
metabolic alkalosis or compensation for respiratory acidosis
A HCO3- level below 24 mEq/L shifts blood into what?
metabolic acidosis or compenstion for repiratory alkalosis