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145 Cards in this Set
- Front
- Back
About 2/3 of the water in the body is what?
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intracellular
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About 1/3 of the water in the body is what?
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extracellular
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What % of body weight is water?
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57%
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What makes up 7% of body water?
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plasma
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What makes up 18% of body water?
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lymph
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What makes up 12% of body water?
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CSF, synovial, ears, eyes, etc.
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How much fluid do you take in daily by food and drink?
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2100 ml/day
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How much fluid do you take in daily by catobolic water?
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200 ml/day
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The regulation of fluid intake is stimulated by what?
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thirst center
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The thirst center located where is sensitive in blood osmotic pressure?
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thirst center
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The thirst center in the hypothalamus stimulates the release of what when osmotic pressure is too high?
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ADH
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What are in major arteries that detect any drop in BP and alert the thirst center?
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pressoreceptors
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What stimulates the thirst center?
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angiotensin II
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With increased BP there is an increase in what?
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GFR and urine
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With increased BOP, what is released which increases water resorption in DCT and CD?
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BOP
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With decreased BP, the kidney releases what?
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renin
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What needs to stay in the blood so BP will stay in increased?
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solute
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What is the specific heat of copper?
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0.092
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What is the term for raising one calorie to one gram?
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high specific heat
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High specific heat has a high ability to maintain what?
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body temperature
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Is water more or less dense when frozen?
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less
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At what temperature is water most dense?
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3.98 degrees celsius
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What happens to water when it becomes less dense?
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it floats
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What is the term for water having a plus and minus charge?
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polarity
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Water has a plus and minus charge which makes it what?
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efficient solvent
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How much energy does it take for water to convert from liquid to gas
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539 cal/gram
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Why is water a very efficient coolant for the body?
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high heat of vaporiztion
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How much energy is needed to raise a gram?
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1 calorie
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What is function of water that converts liquid water into a solid?
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high heat of fusion
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How much energy does it take to convert liquid water into a solid?
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80 cal/gram
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What is the term for the function of water moving up tubes by capillary action?
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high suface tension
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What allows insects to walk on top of water?
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high surface tension
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What % of oxygen is in plasma?
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2%
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What are the functions of water?
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transport O2, CO2 waste, food
Solvent for chemical reactions Diluton for acids Maintain osmotic balance Hydrostatic movement |
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What is an example of hydrostatic movement?
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peristalsis in the gut
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What are the types of electrolytes?
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anions and cations
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What are some examples of anions?
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Cl-, HCO3-, HPO4-2
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What are some examples of cations?
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Na+, K+, MG+2
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Where do electrolytes inonize in?
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solution
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Electrolytes control osmotic pressure because they are what?
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solutes
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Where are the major regions of the body where there are electrolytes?
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plasma, interstitial fluid, intracellular fluid
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What is the content of Na, Cl, protein, and K in plasma?
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high Na and Cl, medium protein, low K
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What is the content of Na, Cl, protein, and K in plasma?
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high Na and Cl, low protein and K
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What is the content of Na, Cl, protein, and K in plasma?
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high protein and K, low Na and Cl
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What is an expression of the number of charges in a solution?
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mEq/L
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Values of electrolytes are measured in what?
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mEq/L
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What is the term for MW in milligrams per L?
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millimoles
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What is the term for # of particles per unit volume?
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milliosmoles
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What impacts osmotic pressure?
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milliosmoles
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What is the term for # of charges per unit volume?
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milliequivalents
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What indicates the charges in a solution?
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equivalents
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What is the typical value of sodium and potassium in plasma?
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Na=140 K=5
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What is the typical value of sodium and potassium in interstitial space?
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Na=135 K=10
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What is the typical value of sodium and potassium in intracellular space?
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Na=10 K=130
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What means "we like it, so we eat it"?
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hedonistic
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What % of potassium in filtrate is lost?
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15%
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Where can you get potassium from?
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food and traces of cytoplasm
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Increased what causes us to dump potassium?
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aldosterone
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What is released when serum calcium is too low?
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parathormone
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What is in bone tissue that extracts calcium from the bone?
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osteoclasts
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Where is calcium absorbed?
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gut and kidney
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What causes 25, hydroxycholecelcipherol to be transformed into Vitamin D?
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parathormone
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What increases the the absorption of calcium from the gut?
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Vitamin D
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What converts 7-dehydrocholesterol in skin to cholecalcipherol?
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UV light
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What converts cholecalcipherol to 25, hydroxycholecalapherol?
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liver
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What converts 23, hydroxycholecalapherol to 1,25 dihydroxycholecelapherol?
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PTH
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What is the abbreviation of 1,25 dihydroxycholecelapherol?
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1,25 (OH)2 D3
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Where is calcitonin release from?
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thryoid gland
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What is released when serum caclium level rises above normal levels?
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calcitonin
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What is one of the most critical balances in live?
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acid base balance
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What are compounds that produce hydrogen ions when placed in solution?
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acids
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What are compounds that accepts hydrogen ions in solution?
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bases
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What are substances that prevent extreme changes in the number of free hydrogen ions or free Oh- in solution?
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buffers
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What are the four buffer systems?
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bicarbonate, hemoglobin, phosphate, and protein
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What is an expression of the H+ concentration in solution?
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pH
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What is the pH of pure water equal to?
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7
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What is the whole name of pH?
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puissance Hydrogen
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As the concentration of H+ increases in solution, what decreases in solution?
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OH-
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What means that for each change in number the concentration changes ten times?
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logarithmic
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The pH scale was named by who?
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Sorensen
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Is the pH of most foods and drugs acidic or basic?
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acidic
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What factors can cause pH change?
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increase or decrease in pH
catabolic acid production ingestion of acid foods and drugs pH is balanced at about 7.4 |
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What terms is used when CO2 is discussed during pH?
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respiratory acidosis or alkalosis
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If you increase CO2 content, what else do you increase?
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H+
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What terms are used with acid production?
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metabolic acidosis or alkalosis
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If your pH shifts below 7.35, what is this called?
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acidosis
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If your pH shifts above 7.45, what is this called?
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alkalosis
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What can cause acidosis?
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hypoventilation, increase in H+, lose bicarbs
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What can cause alkalosis?
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hyperventilation, H+ loss (vomit), increase bicarbs (antacids)
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What can adujust for the change of pH?
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compensation and buffers
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What prevents drastic changes in pH?
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buffers
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How do buffers prevent drastic pH change?
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add or sponge up H+
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What do not completely ionize in solution?
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weak acids
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What type of buffer adds H+ or OH- to shift toward or away from CO2 and H2O?
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carbonic acid/bicarbonate buffer
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What happens when acid are added to blood or lymph?
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shift away from the H+ and HCO3-
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What combines with H+ to become water?
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OH-
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What happens when OH- is added to a solution?
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shifts toward H+ and HCO3-
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What buffer system is present in blood and interstitial fluid and has to do with monobasic and dibasic?
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phophate buffer system
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Is mono or dibasic an H+ donor?
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monobasic
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Is mono or dibasic an H+ acceptor?
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dibasic
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What buffers H+ in RBC's?
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hemoglobin-oxyhemoglobin buffer
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What is a weaker acid, hemoglobin or H2CO3?
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hemoglobin
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What happens when hemoglobin gives up oxygen and takes on a negative charge?
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hemoglobin steals H+ from H2CO3
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What works as a buffer because there is a carboxyl at one end and an amine at the other end?
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protein buffer system
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Kidney excretion helps to maintain what?
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pH
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What two things can the kidneys do to help maintain pH?
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dump H+ and conserve HCO3- or conserve H+ and dump HCO3-
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What kidneys compensate for pH change it is called what?
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metabolic compensation
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What is the increase of H+ content somewhere like in muscle?
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dilution
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What the lungs compensate for pH change what is this called?
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respiratory compensation
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Increased PCO2 in blood causes what?
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decreased pH
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What causes respiratory alkalosis because an increased breathing rate causes more carbon dioxide to be blown ou?
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hyperventilation
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Can you have acidosis or alkalosis at the same time?
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no
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When hyperventilation occurs, the PCO2 value is lowered to what?
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35 mmHg
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What causes respiratory acidosis becasue carbon dioxide is not released from blood?
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hypoventilation
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When hypoventilation occurs, the PCO2 value is increased to what?
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45 mmHg
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What is the normal pH?
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7.35-7.45
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What pH level would cause acidosis?
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below 7.35 (7.38)
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What pH level would casue alkalosis?
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above 7.45 (7.42)
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What is the term for inadequate CO2 release from lungs?
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respiratory acidosis
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What are some examples of respiratory acidosis?
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emphysema, polio, obesity, pulmonary edema, kyphoscoliosis
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What is the term for a decrease of CO2 in blood?
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respiratory alkalosis
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What one thing causes respiratory alkalosis?
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hyperventilation
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What is the term for the HCO3- content is below 24 mEq/L?
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metabolic acidosis
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What is the normal value for bicarbonate (HCO3-)?
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24 mEq/L
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What does "rhe" mean"
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flow
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What can cause metabolic acidosis?
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abnormally high acid producing metabolism
bicarbonate loss renal failure acid drugs |
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What is the term for HCO3- is above 24 mEq/L?
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metabolic alkalosis
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What causes potassium to be placed into the filtrate while sodium is resorbed?
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aldosterone
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Aldosterone activity causes a loss of what which can push someone into alkalosis?
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hydrogen ions
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When pH deviates from normal it moves in one of two directions: what are they?
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toward acidosis or alkalosis
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What is the ratio of H2CO3 to HCO3-?
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1:20
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If the ratio of H2CO3 and HCO3- is less then 1:20 what does the pH shift to?
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acidosis
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If the ratio of H2CO3 and HCO3- is more then 1:20 what does the pH shift to?
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alkalosis
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If the ratio of H2CO3 and HCO3- is 1:1, what is the pH?
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6.2
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When the pH is 6.2 and there are equal amounts of the reactants is reached what is this called?
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pK
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What three values do you get when a lipid panel is done?
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PaCO2, HCO3-, pH
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In normal blood, what is the value of PCO2?
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40 mmHg
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In normal blood, what is the value of HCO3-?
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24 mEq
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In normal blood, what is the value of H2CO3?
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1.2 mEq
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Can you have acidosis and alkalosis at the same time?
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no
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Can you have both repiratory alkalosis and metabolic alkalosis at the same time and same with acidosis?
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yes
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A PCO2 level above 40 mmHg (if acting alone) shitfts blood into what?
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respiratory acidosis or compensation for metabolic alkalosis
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A PCO2 level below 40 mmHg shift blood into what?
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respiratory alkalosis or compensation for metabolic acidosis
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A HCO3- level above 24 mEq/L shifts blood into what?
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metabolic alkalosis or compensation for respiratory acidosis
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A HCO3- level below 24 mEq/L shifts blood into what?
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metabolic acidosis or compenstion for repiratory alkalosis
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