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12 Cards in this Set
- Front
- Back
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draw glycolysis
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this is glycolysis
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draw glycolysis
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kjasgd
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list all the parts of an axon
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axon hillock
dendrites soma axon myelin axon terminals |
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Describe chemical synaptic transmission
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AP arrives at postsynaptic terminus and depolarizes V-sensitive Ca channels, Ca triggers synaptic vesicles loaded with say Ach(put there by a Ach/H atpase) to exocytose NT into cleft, Ach binds AchR causing a conf change to a cation selective pore(NA,K,Ca), causes a excitatory postsynaptic potential EPSP (GRADED!)
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is an EPSP mostly Ca or Na?
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Na
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Miniature endplate potentials MEPPS
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represent quantal release of NT from vesicles
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spatial vs temporal summation
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EPSP's are summated both temporally(in time, regarding frequency) and spacially(along many dendrites)
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Describe an IPSP and how is works
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GABA binds its receptor, causes a Cl conducting pore to form causing hyperpolerization
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two main clases of NT Receptors
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ionotropic and metabotropic
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ionotropic
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ligand gated ion channels direct and rapid postsynaptic effects
Nicotinic |
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metabotropic
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G-protein linked, slower, greater amplification
Muscarinic |
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convergent vs divergent actions of a NT
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divergent: ie NE activated three different signal cascades each of which does 4 different things
convergent: 7 NT's act on 7 receptors which all increase K permeability |
