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12 Cards in this Set

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draw glycolysis
this is glycolysis
draw glycolysis
kjasgd
list all the parts of an axon
axon hillock
dendrites
soma
axon
myelin
axon terminals
Describe chemical synaptic transmission
AP arrives at postsynaptic terminus and depolarizes V-sensitive Ca channels, Ca triggers synaptic vesicles loaded with say Ach(put there by a Ach/H atpase) to exocytose NT into cleft, Ach binds AchR causing a conf change to a cation selective pore(NA,K,Ca), causes a excitatory postsynaptic potential EPSP (GRADED!)
is an EPSP mostly Ca or Na?
Na
Miniature endplate potentials MEPPS
represent quantal release of NT from vesicles
spatial vs temporal summation
EPSP's are summated both temporally(in time, regarding frequency) and spacially(along many dendrites)
Describe an IPSP and how is works
GABA binds its receptor, causes a Cl conducting pore to form causing hyperpolerization
two main clases of NT Receptors
ionotropic and metabotropic
ionotropic
ligand gated ion channels direct and rapid postsynaptic effects

Nicotinic
metabotropic
G-protein linked, slower, greater amplification

Muscarinic
convergent vs divergent actions of a NT
divergent: ie NE activated three different signal cascades each of which does 4 different things


convergent: 7 NT's act on 7 receptors which all increase K permeability