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26 Cards in this Set

  • Front
  • Back
Actin
Thin filaments
Myosin
Thick filaments
I Band
Band of just actin
A Band
Band of overlap between actin and myosin
Z Disc
Ends of actin attach to this disc
Sarcomere
Area of myofibril between two successive Z discs
Titin (attachments and function)
One end attaches to Z disc

Other end attaches to myosin

Springy fiber that holds things in place
NT of nmj
Acetylcholine (re: muscles)
Action potential in muscle
Causes sarcoplasmic reticulum to open, releasing Ca
Filament that slides in muscle contraction
Actin (re: muscle contraction)
Band/disc that changes size in muscle contraction
Z disc (re: muscle contraction)
Myosin head
Has ATPase activity; releases energy for the contraction
Tropomyosin
In resting state, block actin's active site
Troponin
High affinity for Ca

Responsible for pushing tropomyosin deeper into the actin

Allows contraction to occur
Myosin head (re: contraction)
Tilts forward, pulling the actin along

Immediately releases and tilts back

Tilts forward again
Combination of myosin heads
Since each works independently, the more heads causes increased force of contraction
ATP and myosin head
Before contraction, myosin cleaves ATP forcing the head perpendicular to the actin

ADP remains on the myosin head

When myosin attaches to actin, it tilts forward creating force and releasing the ADP
Tension-length relationship
When too long (no overlap of actin and myosin), produce very little tension

When too short (z discs pushing against the myosin), produce very little tension
Length for maximum force from whole muscle contraction
Normal, resting length produces maximum force
Load-velocity relationship
With increasing load, the velocity decreases
Phosphocreatine
Allows ADP to form back into ATP quickly

Uses its own phosphate bond to generate energy
Maximum muscle efficiency
Contraction at moderate velocity
Isometric
Muscle contraction without change in length
Isotonic
Muscle change in length, but no change in tension
Slow muscle fibers (5 properties)
Type I

Smaller fibers

More vasculature

More mitochondria

More myoglobin
Fast muscle fibers (5 properties)
Type II

Larger fibers

Extensive sarcoplasmic reticulum

Lots of glycolytic enzymes

Less vasculature

Fewer mitochondria