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51 Cards in this Set

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  • Back
Corticotropin-releasing horomone (CRH). (origin and effect)
Hyothalamus --> anterior pituitary. Stimulates secretion of adrenocorticotripoic hormone (ACTH)
Gonadotropin-releasing horomone (GnRH)
hypothalamus--> anterior pituitary. Stimulates secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
Prolactin-inhibiting hormone (PH) (Dopamine structure)
Hypothalamus--> Anterior Pituitary. Inhibits prolactin secretion
Somatostatin
hypothalamus--> anterior pituitary. inhibits secretion of growth hormone
thyrotropin-releasing hormone (TRH)
hypothalamus--> anterior pituitary. Stimulates secretion of thyroid-stimulating hormone (TSH)
Growth hormone-releasing hormone (GHRH)
Hypothalamus--> anterior pituitary. Stimulates growth hormone secretion
Pathway of hypothalamic hormones to anterior pituitary
Hyothalamic neurons secete hormones into primary capillary plexus--> hypophyseal portal veins (where they stimulate or inhibit release of hormones from anterior pituitary)--> anterior pituitary hormones secreted into 2ndary capillaries
trophic hormones stimulate hormone secretion in other glands (name them) (come from)
All come from anterior pituitary. GH (growth hormone), TSH (thyroid-stimulating hormones), ACTH (adrenocorticotropic hormone), FSH (follicle stimulating hormones), LH (luteinizing hormone), PRL (prolactin)
Trophic hormones can cause
hypertrophy of target organ at high concentrations
ACTH (adrenocorticotropic hormone): target tissue, actions, regulation of secretion
effects adrenal cortex, stimulates secretion of glucocorticoids, stimulated by CRH (corticotropin-releasing hormone)/inhibited by glucocorticoids
TSH (thyroid stimulating hormone) target tissue, actions, regulation of secretion
thyroid gland, stimulates secretion of thyroid homones, stimulated by TRH (thyrotropin-releasing hormones), inhibited by thyroid hormone
GH (growth hormone) target tissue, actions, regulation of secretion
Most tissue, promotes protein synthesis and growth, lipolysis and increased blood glucose, inhibited by somatostatin, stimulated by growth hormone-releasing hormone.
FSH: target tissue, actions, regulation of secretion
tagets gonads, promotes gamete productinon and stimulates estrogen production in females. Stimulated by GnRH (gonadotropin releasing hormone), inhibited by sex steroids and inhibin
Prolactin (PRL) target tissue, actions, regulation of secretion
targets mammary glands, other sex accessory organs. Promotes milk production in lactating females, additional actions in other organs
LH: target tissue, actions, regulation of secretion
Targets gonads, stimulates sex hormone secretion, ovulation and corpus leteum formation in females, stimulates testerone secretion in males
Pathway of hypothalmic hormones to posterior pituitary
Hypothalamic neurons synthesizes oxytocin and ADH, they're transported along hypothalamic-hypophyseal tract to the posterior pituitary. Then they're stored in axon terminals along post pituitary, then released to the blood.
Posterior pituitary hormones & efffects
Anti-diuretic hormone (ADH/vasopressin): promotes water reabsorption in kidneys, urine decrease
Oxytocin: stimulates smooth muscle contraction, especially during parturition (birthing). Promotes milk let down (milk ejection reflex)
Adrenal cortex hormones:
release hormones called cortiocosteroids. Zona glomerulosa, zona fasciculata, zona reticularis
Adrenal cortex hormones plus their secretions (Girls from russia Make good sex)
zona Glomerulosa: Mineralcorticoids
Zona fasciculata: glucocorticoids
Zona retcularis: sex steroids
Zona glomerulosa:
secretes mineralcorticoids.
Regulate Na+ and K+ balance
Aldosterone: Sodium and water retention; while excreting potassium
Zona fasciculata
Secretes glucocorticoids. Regulate glucose metabolism and that of other organic molecules.
Cortisol: stimulate glucose formation and inhibit utilization of glucose.
zona reticularis
secrete sex steroids
Weak androgens like Dehydropepiandrosterone (DHEA)
adrenal cortex regulated by ____, adrenal medulla regulated by
hormones, neural innervation
adrenal medulla secretes
epinephrine, norepinephrine which cause sympathetic-like response, activated by stress (flight or flight)
Goiter formation: caused by __
hypothyroidism- low iodine intake, nutritional deficiency, endemic goiter. hyperthyroidism- autoimmune response, graves disease
Pancreas endocrine cells located in ____, two types and their secretions
islets of langerhans, alpha cells secrete glucagon, beta cells secrete insulin
insulin and glucagon have ___ relationship. After meal insulin ____, and glucagon ___
insulin increases, glucagon decreases
After meals, blood glucose/amino acid/fatty acids/ ketone bodies __
decrease
Diabetes Type I: offset, caused by destruction of ___, lack of, conditions
adolescent onset, caused by destruction of beta cells, lak of insulin secretion leads to extracellular hyperglycemia and increase lipolysis, ketonemia, diabetic ketoacidosis, 10%
Type II diabetes mellitus: offset, condition
non insulin dependent, maturity-onset diabetes, insulin resistant, normal or elevated insulin initally, relative insulin deficiency, obese, 90%
Pineal gland hormone
melatonin, biological clock, night/day
Adipose tissue (hormones, target organs, effects)
leptin, hypothalamus, suppresses appetite
adrenal cortex (hormones, target organs, effects)
glucocorticoids aldosterone, liver/muscles/kidneys, glucocorticoids influence glucose metabolism, aldosterone promotes Na retention, K excretion
adrenal medulla (hormones, target organs, effects)
epinephrine, heart/bronchioles, blood vessels. Causes adrenergic stimulation.
heart (hormones, target organs, effects)
atrial natriuretic hormone, kidneys, promotes excretion of Na in urine
hypothalamus (hormones, target organs, effects)
releasing and inhibiting hormones, anterior pituitary, regulates secretion of anterior pituitary hormones
small intestine (hormones, target organs, effects)
secretin and chloecystokinin, stomach/liver/pancreas, inhibits gastic motility and stimulates bile and pancreatic juice secretion
Islets of langerhans (pancreas) (hormones, target organs, effects)
insulin, glucagon, effects many organs/liver/adipose tissue. Insulin promotes cellular uptake of glucose and formation of glycogen and fat, glucagon stimulates hydrolysis of glycogen and fat.
kidneys (hormones, target organs, effects)
erthropoietin, bone marrow, stimulates red blood cell production
Liver (hormones, target organs, effects)
somatomedins, cartilage, stimulates cell division and growth
Ovaries (hormones, target organs, effects)
estradiol-17beta and progesterone, female reproduction tract and mammary glands, maintains structure of reproduction tract and promotes secondary sex characteristics
parathyroid glands
parathyroid hormone, bone/small intestine/kidneys, increases Ca2+ concentration in the blood
pineal gland (hormones, target organs, effects)
melatonin, hypothalamus and anterior pituitary, affects secretion of gonadotrophic hormones
anterior pituitary (hormones, target organs, effects)
trophic hormones, endocrine glands and other organs, stimulates growth and development of target organs and stimulates secretion of other hormones
posterior pituitary (hormones, target organs, effects)
antidiuretic hormone, oxytocin, kidney/ BV uterus, mammary glands, antidiuretic hormone promotes water retention and vasoconstriction, oxytocin stimulates contraction of uterus and mammary secretory units
skin (hormones, target organs, effects)
1,25-dihydroxvitamin D, small intestine, stimulates absorption of Ca2+
stomach (hormones, target organs, effects)
gastrin, stomach, stimulates acid secretion
testes (hormones, target organs, effects)
testosterone, prostate/seminal vesicles/other organs, stimulates secondary sexual development
thymus (hormones, target organs, effects)
thymopoietin, lymph nodes, stimulates WBC production
thyroid gland (hormones, target organs, effects)
thyroxine (T4) and triidothyronine (T3), cacitonin. Most organs, thyroxine and triiodothyronine promote growth and stimulate basal rate of cell respriation (basal metabolic rate), calcitonin may participate in the regulation of blood Ca2+ levels
Pituitary gland attached to the ___ by the ___. Anterior is ___ tissue, posterior is _____ tissue,
hypothalamus, infundibulum, glandular, neural