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131 Cards in this Set

  • Front
  • Back
Automonic Nervous System (ANS)
regulates organs and organ systems, and smooth muscles and glands
also provides information to the CNS
Smooth muscle
active on their own
ANS promotes/inhibits
ANS has 2 neurons
Preganglionic neuron: cell body in brain or spinal cord
Postganglionic neuron: synapses and an autonomic ganglion
2 Divisions in ANS
Sympathetic: fight or flight
Parasympathetic: feed or breed
Sympathetic
very fine tuned responses
very short preganglionic fibers
postganglionic very long
Divergence
(short) preganglionic branch to synapse with number of longer postganglionic neurons
Adrenal Medulla
realeases epinephrine (lots) and norepinephrine (less) in blood in response to preganglionic stimulation
Parasympathetic
slower
alot more specific
long preganglionic, short postganglionic
Both sympathetic and parasympathetic PREGANGLIONIC release
ACh
Parasympathetic POSTGANGLIONIC also release
ACh
Most sympathetic POSTGANGLIONIC release
norepinephrine, but release some ACh
Unusual Synapses
Varicosities
Agonists
drugs the promote actions of a NT
Antagonists
drugs the inhibit actions of a NT
Nicotinic blocked by
Curare
Muscarinic blocked by
Atropine
Dual innervation
supplied by both sympathetic and parasympathetic
Medulla Oblongata
most directly controls activity of ANS
Hypothamamus
centers for control of body temp, hunger, and thrist
Limbic system
responsible for visceral responses that reflect emotional states
Endocrine Glands
are ductless and secrete hormones into bloodstream
Neurohormones
secreted into blood by specialiezed neurons
Amine
derived from tyrosine or trytophan
Polypeptide and protein
horomones are chains of amino acids
Glycoproteins
LH, FSH, TSH
Steriods
lipids derived from cholesterol
Prohormones
precursors of hormones
ex/proinsulin
Prehormones
precursors of prohormones
ex/preproinsulin
hormone interaction
2 hormones are synergistic if work together to produce an effect
Priming effect or upregulation
hormone induces more of its own receptors in target cells
Desensitization or downregulation
long exposure to high levels of polypeptide hormone
Thyroid Hormone Action
T4 must be converted into T3

T3 can float directly into cells and get the job done
cAMP
mediates effects of many polypeptide and glycoprotein hormones
Pituitary Gland
Acts as an endocrine gland
Posterior and Anterior lobes
controlled by hypothalamus
Growth hormone
promotes growth, protein synthesis and movement of amino acids
Thyroid stimulating hormone (TSH)
stimulates thyroid to produce and secrete T4 and T3
Adrenocorticotrophic hormone (ACTH)
stimulates adrenal cortex to secrete cortisol
Follicle stimulating hormone (FSH)
stimulates growth of ovarian follicles and sperm production
Luteinizing hormone (LH)
causes ovulation and secretion of testosterone in testes
Prolactin (PRL)
stimulates milk production by mammary glands
Feedback control
short feedback loop, negative feedback, and positive feedback
Antidiuretic hormone
promotes H2O conservation by kidneys
oxytocin
stimulates contraction of uterus
Adrenal glands
another connection between endocrine and nervous system
Cortisol
inhibits glucose utilization/stimulates gluconegenesis
aldosterone
stimulates kidneys to reabsorb Na+ and K+
Basil Metabolic Rate
the way we chew up energy
Skeletal Muscles
attach to bon on each end by tendons
Flexors
decrease angle of joint
Extensors
increase angle of joint
skeletal muscle structure
highly organized
striated muscle
only contract in one direction
Motor unit
includes each motor neuron and all fibers it innervates
Myofibrils
individual protein
Structure of myofibril
A ban is dark contains filaments
I band is light contains thin filaments
Myosin wants to bind to?
actin
in mysoin what must get burned
ATP
Sliding filament theory
muscle contracts cuz thin filaments slide over and between thick filaments
Troponin-tropomyosin system
control of cross bridge attachment to actin
Tropomyosin
interfers with myosin grabbing actin
when calcium is taken away the process
reverses
Sarcoplasmic reticulum
a calcium reservoir in muscle
APs in T tubules cause release of Ca++ from
cisternae
Cardiac Muscle
striated like skeletal but involuntary like smooth
Smooth muscles
has no sacromeres but has gap junctions
Smooth muscle is very good at?
contracting and sustaining that contraction
cardiovascular
heart pumps blood
blood vessels carry blood from heart to cells and back
Cardiovascular system includes:
arteries, arterioles, capillaries, venules, veins
Lymphatic system
picks up excess fluid filtered out in capillary beds and returns it to veins
blood consist of:
formed elements (cells) and plasma (fluid part)
when blood centrifuged, blood seperates:
Formed elements on bottom and plasma on top
adema
decrease in proteins in blood
3 types of plasma proteins
albumins, globulins, and fibrinogen
albumins
create colloid osmotic pressure that draws H2O from interstitial fluid into capillaries to maintain blood volume and pressure
Globulins
carry lipids or are antibodies
Fibrinogen
serves as clotting factor
Serum
fluid left when blood clots
formed elements
Erythrocytes (RBCs) and leukocytes (WBCs)
leukocytes
has nucleus
can crawl around
squeeze through capillary walls
Granular Leukocytes
help detoxify foreign substances and release heparin
Agranular leukocytes
phagocytic and produce antibodies
Include lymphocytes and monocytes
Megakarocytes
produce nuclear platelets
Thrombocytes
lack nucleus and are not true cells
Hematopoiesis
formation of clood cells from stem cells
Erythropoiesis
formation of RBCs
Leukopoiesis
formation of WBCs
Hemostasis
stop loss of blood and maintain blood pressure
Vasoconstriction
restricts blood flow to area
Role of fibrin
RBCs get caught
Clot forms structure for rebuilding of vessel
Conversion of Fibrinogen to fibrin (2 Pathways)
Intrinsic
Extrinsic
Intrinsic
Involves conversionof prothrombin to thrombin
Thrombin converts fibrinogen to fibrin
Extrinsic
damaged tissue can release clotting factors that triggers a clotting shortcut
Heart has 4 chambers
2 atria (Left and right)
2 Ventricles (Left and Right)
Atria
receive blood from venous system
Ventricles
pump blood to arteries
Left Ventricle
works 7x more than right
Pulmonary Circulation
path of blood from right ventricle through lungs and back to heart
Systemic circulation
path of blood from left ventricle to body and back to heart
Atrioventricular
Seperates Atrium and ventricle
Tricuspid valve
between right atrium and ventricle
Bicuspid valve
between left atrium and ventricle
Semilunar Valves
Pulmonary Valve
Aortic Valve
Systole
refers to contraction stage
Diastole
refers to relaxation stages
SA node
functions as pacemaker
Arteries
expand during systole and recoil during diastole
Arteries (cont.)
Provide most resistance and greatest drop in pressure in circulatory system
capillaries
provide extensive surface area for exchange
"place where buisness of the blood gets done"
Veins
bigger than arteries
very stretchy, weak, and thin
low BP
contain majority of blood in circulatory system
Lymphatic system (3 functions)
Transports interstitial fluid back to blood
Transports absorbed fat from small intestine to blood
helps provide immunological defenses against pathogens
Lymph is carried from lymph capillaries to:
Lymph ducts to lymph odes
Cardiac Output (CO)
is volume of blood pumped/min by each ventricle
Stroke Volume (SV)
volume of blood pumped/beat by each ventricle (mL/beat)
Heart Rate (HR)
the number of beats/minute
Cardiac Rate is controlled by
autonomic
sympathetic increase cardiac performance
Parasympathetic decrease cardiac performance
SA node is:
main controller for HR
Parasympathetic releases:
ACh
Norepinephrine and epinephrine
increase or stimulate HR
ACh:
Decrease HR
Stroke Volume (3 variables)
End diastolic volume (EDV)
Total Peripheral Resistance (TPR)
Contractility
End Diastolic Volume (EDV)
amount of blood in a ventricle when it is relaxed
Total Peripheral Resistance (TPR)
amount of work the heart has to work against
Regulation of Stroke volume
EDV is preload
TPR is afterload
Ejection Fraction
SV/EDV
Venous Return
resvoir that resides in our veins
Hydrostatic
amount of squeezage
Vasodilation
decreases resistance, increases blood flow
Vasoconstriction
decrease blood flow
Blood Pressure
Increase or Decrease in sympathetic
Blood Pressure (cont.)
mainly controlled by HR, SV, and peripheral resistance
Pulse pressure
(systolic pressure) - (diastolic pressure)
Mean Arterial pressure (MAP)
represents average arterial pressure during cardiac cycle