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58 Cards in this Set

  • Front
  • Back
what are the 5 functions of the heart?
1 - self nutrition
2 - regular self excitation
3 - effective contraction/relaxation
4 - effective intra-cardiac blood flow path
5 - reulation of Pre-Load (pressure)
What is the heart disfunction concerned with "self nutrition"?
ischemia - not enough O2 supplied
What is the heart disfunction concerned with self excitation?
arrythmia
What is the heart disfunction concerned with effective contraction?
cardiomyopathies
What is the heart disfunction concerned with intra-cardial blood flow?
valve/septal defects
what is a septal defect?
a hole in the intra-atrial or intraventricular septum
What is the heart disfunction concerned with regulation of pre-load?
congestive heart failure - can't supply body's needs
2 major inflow vessels of heart?
inf/sup vena cava, pulmonary veins
2 major outflow vessels of hearts?
aorta, pulmonary trunk
Valve between RA and RV?
tricuspid
valve after R ventricle?
Pulmonic valve
valve after L ventricle?
aortic valve
valve between LV and LA
mitral (bicuspid) valve
3 major types of cardiac muscle?
atrial, vventricular, specialized pacemaker muscle
What allows cardiac cells to function in concert? (2 things)
intercalated discs and gap junctions
What type of metablosim do cardiac cells use? what cell structure does this necessitate?
Aerobic metabolism, needing mitochondria
What is the initial pacemaker of the heart?
SA NODE
describe the path of the electrical current of the herat?
SA node - atrial depol - AV node - purkinje fibers - ventricle depol
label 0-4
4 - RMP
0 - rapid depolarization
1 - outward K/Cl
2 - calcium influx
3 - repolarization
what is 0 due to?
FAST influx of Na thru voltage gated
what is 1 due to?
outward K/Cl
what is 2 due to?
calcium INFLUX
What is 3 due to?
efflux of K thru VOLTAGE
Where is ARP?
RRP?
ARP - 0--->1/2 of 3
RRP - 1/2 of 3 to 4
When are non-pacemaker cells able to take over funciton of heart beat?
RRP
What is the normal blood volume of a person?
5 L
What is comploiance of systemic veins measured in? what is the normal value?
mL/ mmHG
50
mean systemic filling pressure?
units?
normal value?
measure of DEGREE OF FILLING OF CIRCULATION - driving pressure
mmHg
7
Extravasulcar pressure?
Skeletal muscle tone
Central Venous Pressure?
unites?
usualy value?
mmHg
RAP -determines DIASTOLIC filling of RV
0 for RAP
vanous return
units
value
L/min
5
blood to R.A - cardiac output follows this value
Cardiac output
unit
value
L/min
blood into aorta
5
same as venous return
Total peripheral resistance
sum of resistance impeding floow between aorta and R.A
mmHg/ (L/min)
Mean atrial pressure
100 mm Hg normal
time of arterial pressure - pressure for flow to tissues
Percentages of where blood is
Pulmonary?
Systemic?
Heart?
systemic - 85%
heart - 5%
pulmonary circ - 10%
% of blood in the systemic circ
veins?
arteries?
capillaries?
veins - 65%
arteries - 13%
cap - 7%
6 vascular segments?
veins
large arteries
arterioles
capillaries
metarterioles
venuoles
veins
large arteries
arterioles
capillaries
metarterioles
venuoles
Which responds to nerves?
veins
veins
large arteries
arterioles
capillaries
metarterioles
venuoles
which stores energy
large artery
veins
large arteries
arterioles
capillaries
metarterioles
venuoles
which responds to local factors for resistance?
arterioles and metarteroiles
veins
large arteries
arterioles
capillaries
metarterioles
venuoles
which increases permeability with inflammatoin?
venuoles
a - 100
b - 98
c - 85
d - 30
e - 10
f - 98
g - 85
h - 30
i - 10
j - 0
a - aorta/large arteries
b - regional arteries
c - arterioles
d - capillaries
e large veins
Best answer: The blood flow toe each tissue of the body is ALMOST ALWAYS controlled by?
tissue's metabolic needs
cardiac output is controlled mainly by
sum of systemic tissue flows (venous return to R.A.)
Arterial pressure is controlled iNDEPENDENTLY of 2 things:
local blood flow and cardiac output
guyton's 3 principles?
1 - blood flow to tissue goverend by metabolic needs
2 - sum of systemic tissue flows controls cardiac output
3 - local blood flow and cardiac output are indepent of arterial pressure
Ohm's law
MAP = ?
(Q x TPR) + RAP
Laminar flow vs. turbulent flow
laminar is linear, streamline
turbulent is murmur causing
doubling length of tube
doubling diameeter of tube
doubling viscocity of blood
which decreases resistance?
doubling diameter, by 1/16
what is hematrocrit? normal level?
40 - percent of blood that is cells
27
20
20
15
8
7
5
splanchnic
renal
skeletal muscle
cerebral
fat/bone
skin
coronary
what are the 2 highest priority organs? what mechanism controls their flow?
brrain and heart - local control
what are the 2 lowest priority organs for blood? what controls them?
kidney and skin - baroreceptor reflex
rank the following in relative blood flow. what are the units?
GI brain kidney heart other
kidney
GI
heart
brain
other
ml/min/100g
which has the lowest oxygen in the venous blood leaving its capillary bed?
heart
2 esential purposes of CV system
blood flow
capillary exchange