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63 Cards in this Set
- Front
- Back
4 layers of GIT?
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mucosa
submucosa muscularis externa serosa |
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Where are Peyer's patches and M Cells located? What portion of the GIT is it typically found?
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in the lamina propria of mucosa layer
ileum of small intestine |
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Mucin is in the ____. What is it's function.
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mouth
lubrication |
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Amylase is in the ____. What is it's function.
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mouth and pancreas
carbohydrate digestion |
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Muramidase is in the ____. What is it's function.
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Mouth
attack bacteria cell walls |
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Lactoferrin is in the ____. What is it's function.
|
mouth
binds to iron, prevents biofilm formation |
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Match the stomach gastric juice to it's cell producer.
mucin pepsinogen HCl + IF gastrin |
neck cell
chief cell parietal cell G cell |
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What is chyme?
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gastric juices and food
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What is pancreatic juice?
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chyme and pancreatic secretions
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What is bile?
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bicarbonate and bile salts
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What makes the small intestine so good at digestion and transportation?
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large surface area due to villi and microvilli
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What is the main site of digestion and absorption of the GIT?
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small intestine
|
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What prevents infection in the saliva of the mouth
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muramidase
lactoferrin |
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What is the primary water absorber of the GIT?
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large intestine
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The stomach has a pH or about ____.
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2
|
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What protects the rest of the body from the pH in the stomach? What results from a breakdown of this
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mucosal lining
peptic ulcer |
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Materials absorbed in the GIT move to the ____ via the ____, are processed and then move through the ____ into circulation.
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liver
hepatic portal vein hepatic vein |
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What is secreted from the pancreas that neutralized the acid from the stomach? WHere does this occur?
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bicarbonate
duodenum |
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Where do secretions from the liver and pancrease mix?
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Ampula of Vater
from the the common bile duct and pancreatic duct |
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What regulates liver and pancreatic secretions into the duodenum?
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Sphincter of Oddi
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Where is bile produced?
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liver
|
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Where is bile stored?
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gall bladder
|
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What cells take material from the blood and move it to bile for excretion?
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hepatocytes
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What three organs secrete products into the duodenum?
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liver
gall bladder pancreas |
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WHat organ does not produce their products in acini?
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liver
|
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What makes up bile?
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bile salts + bicarbonate
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Where is salivary amylase inactivated and why?
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stomach
low pH |
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What is the endpoint of amylase digestion?
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maltose and limit dextrins
|
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What are the four disacharides listed?
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dextrins
sucrose lactose maltose |
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What is the order of sugar breakdown? Where does each happen and by what enzyme?
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sugar
POLYSACHARIDES - amylase in mouth, pancreatic amylase DISACHARIDES - brush border enzymes in duodenum MONOSACHARIDES |
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What can't amylases break down?
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branch points
disacharides |
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In carb absorption, what goes through secondary active transport, and what goes through facilitated transport?
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secondary - glucose & galactose
facilitated - fructose |
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What are the three monosacharides?
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glucose
fructose galactose |
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What ion drives glucose and galactose transport across a membrane?
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2 Na+ for every 1 of either
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What is the carrier for glucose and galactose?
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Glut2
|
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What is the carrier for fructose absorption?
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Glut4
|
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Which monosacharide has a strong gradient across an absorption membrane?
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fructose
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Which monosacharides have no gradient across an absorption membrane?
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glucose
galactose |
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What side of the membrane is Glut 2, blood or lumen?
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blood
|
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Proteins are absorbed through ____ with ____.
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secondary active transport
Na+ |
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Pepsinogen comes from ____ cells in what organ.
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chief
stomach |
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HCl comes from ____ cells in what organ?
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parietal
stomach |
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What organ does trypsinogen come from?
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pancreas
|
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How does the body solve the lipid solubility problem?
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emulsification
|
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Emulsifiers are ____.
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amphipathic
|
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Emulsification does what to surface area of fat glubules?
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increases it
|
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What happens to pancreatic lipase if colipase is not present?
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Bile salts repel the lipase
|
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What does lipase do to triglycerides?
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breaks them into a monoglyceride and two fatty acids
|
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No B12 = ____ anemia
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pernicious
|
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Which vitamins move with lipids
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fat soluble A,D,E,K
|
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What must be present for pancreatic lipase to work?
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colipase
|
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What does the triglyceride get packaged into?
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chylomicrons
|
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The enteric nervous system has ____ CNS input?
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no
|
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In the ENS the ____ deals with secretion and the ____ deals with motality.
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submucosal
myenteric |
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Which reflex has CNS input? Where does it go to get to the ENS?
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long reflex pathway
ANS CNS -> ANS -> ENS |
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What stimulates cells like pepsinogen, and parietal cells?
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gastrin
|
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Increased pH stimulates ____ in the duodenum.
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secretin
|
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Increased proteins and fats stimulates ____ in the duodenum.
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CCK
|
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What organs secrete bicarbonate?
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liver
pancreas |
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What does secretin stimulate?
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liver bile
pancreatic bicarbonate |
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What does CCK stimulate?
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gallbladder contraction
sphincter of oddi relaxation |
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____ increases the force of intestinal motility.
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gastrin
|
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____ decreases the force of intestinal motility.
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CCK
secretin GIP |