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40 Cards in this Set

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There is ____ mL/kg of blood in the body
80
Order of hematocrit from high to low?
newborn
male
female
A low hematocrit indicates ____
anemia
A high hematocrit indicates ____
polycythemia
One would have a _____ hematocrit at high elevation. Why?
high
increases oxygen carrying capacity
High body water would result in ____ hematocrit
low
Low body water would result in ____ hematocrit
high
Anemia due to nutritional deficiencies is related to low ____ and ____.
iron
folic acid
Anemia due to pernicious is related to no ____ in the ____ resulting in no ____ absorption in the ____.
IF
stomach
B12
small intestine
Anemia due to aplastic is related to ____.
bone marrow blood cell production
Anemia due to renal is related to low production of ____.
EPO (erythropoietin)
Anemia due to hemolytic is from what?
increased breakdown of RBC
What diseases are associated with hemolytic anemia
malaria
mycoplasma
autoimmune
sickle cell anemia
thalassemia
What is hemorrhagic anemia?
blood loss
What are the three types of polycythemia?
primary - overproduction RBC in bone marrow
secondary - increased EPO
relative - decrease in plasma
Viscous blood could be an indicator of what?
polycythemia
What is the % breakdown of plasma
90 % water
9 % organic
1 % inorganic
What is a plasma donation used for?
coagulation disorders
Rank blood cells from high to low
erythrocytes
platelets
leukocytes
What is the main source of O2 in the blood?
O2 bound to Hemoglobin (Hb)
Low O2 causes the kidneys to release ____ causing what?
EPO
erythropoyesis - production of RBC in bone marrow
How is iron transferred in the blood? Why?
transferrin
free iron is toxic
What plasma protein is responsible for colloidal pressure?
Albumins
What plasma protein transports lipids, hormones, etc
globulins
What plasma protein is synthesized in the liver and is important for clotting?
fibrinogen
What makes RBCs flexible
spectrin
How much O2 per g of Hb
1.3
High levels of unconjugated bilirubin indicate ____ jaundice? Why?
prehaptic
hemolysis overwhelms the liver
High levels of conjugated bilirubin indicate ____ jaundice? Why?
postepatic
bile duct obstruction - can't be excreted
High levels of unconjugated and conjugated bilirubin indicate ____ jaundice? Why?
hepatic
liver damage
What are the 3 steps of hemostasis?
vascular spasm
platelet aggregation
coagulation cascade
What are the genetic clotting disorders?
Von Willebrand disease
Hemophelia
What is the nutritional clotting disorder?
vitamin K deficiency
Factor VIII is lacking in Hemophelia ____.
A
Factor IX is lacking in Hemophelia ____.
B
Factor XI is lacking in Hemophelia ____.
C
Warfarin - ____
vit K antagonist
Heparin - ____
blocks thrombin
Hirudin - ____
blocks thrombin
Draculin - ____
inhibits factor IX and X