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52 Cards in this Set

  • Front
  • Back
Is cartilage vascular or avascular?
Avascular

Which tissue is avascular?
What are the specialized cells of cartilage called?
Chondrocytes

Which tissue are these specialized for?
Why do chondrocytes have pale or vacuolated areas?
Cytoplasm has glycogen, lipid, and large golgi apparatus

This space with the above components are found in what cell?
Why do chondrocytes have a lacuna?
During preparation, glycogen and lipids are lost and the cell will shrink leaving a surrounding space.
Is the lacuna in chondrocytes seen in LM or EM?
LM only!
The 3 Cartilages all have what type of collagen fibers?
Type II
What color is the ECM of cartilage in H&E staining?
Basophilic because the ECM contains sulfate groups on its proteoglycans which bind hemotoxylin.
Why is the lacuna typically more intense basophilic?
Because sulfate groups are present in highest concentrations around the lacunae.
Can you tell the difference by looking at staining an old person vs. a young person?
Yes, staining of cartilage from older individuals are less intensely basophilic than young individuals.
What are the 3 types of cartilage?
Hyaline, Elastic, Fibrocartilage
What tissue is found in the Fetal skeletal tissue, epiphyseal plates, articular surface of synovial joints, costal cartilages of the rib cag, cartilages of the ansal cavity, laryn, rings of trachea and plates in bronchi
Hyaline Cartilage
What tissue is found in the Pinna of external ear, external acoustic meatus, auditory tube, cartilages of larynx
Elastic Cartilage
What tissue is found in the IV disks, pubic symphysis, knee joint
Fibrocartilage
Which cartilage provides resistance to compression, cushioning, structural support?
Hyaline
Which cartilage provides flexible support?
Elastic
Which cartilage resists deformation under stress?
Fibrocartilage
Which cartilages have pericondrium?
Hyaline and Elastic
Which cartilages undergo calcification?
Hyaline and Fibrocartilage
What are the major cell types of the cartilages?
Chondroblasts and chondrocytes
Which cartilage contains fibroblasts?
Fibrocartilage
Which cartilage contains Type II collagen fibrils
All: hyaline, elastic, and fibrocartilage
Which cartilage contains Type II and elastic fibers?
Elastic cartilage
Which cartilage contains Type II and Type I collage fibers
Fibrocartilage
How do the 3 cartilages grow?
Interstitially and appositionally, very limited in adults
Is the repair capability good for the 3 cartilages?
Very limited capability, commonly forms scar resulting in fibrocartilage formation.
Which cartilage has perichondrium containing blood vessels surrounding non-articular cartilage?
Hyaline
Which cartilage has chondrocytes in isogenic pairs?
Hyaline
In which cartilage are the chondrocytes closer together (less matrix) than in hyaline?
Elastic
Which cartilage has ECM that includes fine elastic fibers and lamellae?
Elastic
In which cartilage can deposits of adipose tissue occur?
Elastic
Which cartilage has chondrocytes that are sparse, arranged linearly, and separated by thick collagen bundles?
Fibrocartilage
Which cartilage has ECM that resembles Dense CT?
Fibrocartilage
Ground bone is used to prepare?
Matrix organization-osteons, cells are destroyed, can use dyes such as India ink
Decalcified bone is used to prepare?
Cells but treated with acids to dissolve inorganic components, lamella preserved, can use to see blood vessels, and periosteum
Which cell of the bone secrets collagen and ground substance of osteoid?
Osteoblasts
Which cells are cuboidal or polygonal and located on the surface of the forming bone?
Osteoblasts
Which cell differentiates from osteoblasts, surrounded by matrix, shrunk, and surrounded by a TRUE lacuna?
Osteocytes
Which cell removes bone during development?
Osteoclasts
How is the cytoplasm stained in Osteoblasts?
Basophilic
How is the cytoplasm stained in Osteoclasts?
Eosinophilic
Which cell has multiple nuclei and present and contains Howship's lacuna?
Osteoclasts
How is the bone matrix stained?
Eosinophilic
Which has Golgi and RER (Obsteoblasts or Osteocytes?)
Osteoblasts
Matrix of developing bone contains what staining?
Both basophilic and eosinophilic
What are the zones of Endochondral bone formation?
Zone of reserve cartilage
Zone of proliferation
Zone of maturation/hypertrophy
Zone of Calcified cartilage
Zone of resorption
Zone of ossification
What are intramembranous bone formation?
Limited to those bones that are not required to perform an early supporting function
What zone has chondrocytes with relatively little intervening matrix?
Zone of reserve cartilage
What zone contains parallel stacks of chondrocytes, daughter cells resulting from rapid mitosis
Zone of proliferation
What zone contains enlarged chondrocytes with pale cytoplasm (glycogen)
Zone of maturation/hypertrophy
What zone has chondrocytes die, lacunae are empty, and matrix calcifies (basophilic)
Zone of calcified cartilage
What zone has blood vessels and connective tissue invade area of dying chondrocytes?
Zone of resorption
What zone has bone cells that are present and ossified matrix is eosinophilic
Zone of ossification