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42 Cards in this Set

  • Front
  • Back
Categories of Neurotransmitters
* I. Acetylcholines
* II. Monoamines
* III. Amino Acids
* IV. Peptides
* V. Other
II. Monoamines
(Every Monoamines contains one N2H(2 Nitrogen's & a Hydrogen molecule) group. Monoamines are looked at most when treating psych disorders.
* A. Catecholines
* B. Indolemines
* C. Histamines
A. Catecholines
* 1. DA
* 2. NE
* 3. E
B. Indolemines
* 1. Melatonin
* 2. Serotonin
III. Amino Acids (Every Amino Acids contains an Amine & Carboxyl group (COOH))
* A. GABA
* B. Glycine
* C. Glutamate
* D. Aspartate
IV. Peptides (A chain of Amino Acids. Peptides are the only NT group we are learning about that also functions and Hormones.)
* A. Substance P
* B. Endorphin
* C. Neuropeptide S
* D. Neuropeptide Y
* E. Vasopressin
* F. Oxytocin
V. Other
* A. Lipids
* B. Nucleotides
* C. Gases
Acetylcholine (ACh)
The molecules Acetate & Choline together
Where do you get Acetylcholine?
* You get the Acetate from acids in your diet.
* You get the Choline from Soy, Peanuts, Cauliflower…
What is ACh broken down by?
Acetylcholine Esterase
Action is PNS by ACh
Activates every muscle in the body.
Action in the CNS by ACh
• Learning & Memory, primarily in Hippocampus.
• Sleep & Arousal, particularly in Reticular Activating System (RAS).
• REM sleep, in the Pons.
• Active in Parasympathetic NS.
• Depending on person, Has to do with depression. That’s what Tricyclic Anti-Deps were trying to treat. Tricyclic Anti-Deps lower Acetylcholine levels. Side effects are memory issues and messes with sleep patterns.
Catecholines
* Chemically changed by:_MAO (Monoamine Oxidase – the enzyme which breaks down the Catecholines)_.
* Catecholines are very similar to each other.
Dopamine (DA) Plays a role in:
* Sympathetic arousal:
* Wakefulness:
* Hormones:
* Pleasure and affect:
* Sex:
* Food:
* Any drug or other addiction:
* Sleep:
* Mental Disorders:
Increase in DA in Limbic system(emotion center) is seen in:
Schizophrenia (increase of hallucinations, flat affect(socially withdrawn)). The drug Thorazin alleviates some of these symptoms.
Decrease of DA seen in:
Parkinson’s.
Dysfunction of DA level in:
Eating Disorders.
Dysfunction of DA:
Affects attention in learning and memory.
D4 receptor has to do with:
Thrill seeking.
Norepinephrine (NE) plays a role in:
* Arousal
* Active emotions
* Disorders
* Learning and Memory
* Eating
Epinephrine (E) plays a role in:
 Sympathetic NS
 Generalized anxiety
 Learning and memory
 Shyness and introversion
Indolamines:
- What is the precursor of Melatonin & Seratonin?
* Triptophan
What NT is key for sleep?
Melatonin
What NT is linked with Depression more than any other NT?
Seratonin
90% of what NT is found in the Intestines?
Seratonin.
Antipsychotic drugs do what?
Block Serotonin Receptors
Anti-Anxiety drugs do what to Serotonin?
Increase Serotonin levels
Hallucinogen Drugs do what to Serotonin?
Mess up Serotonin levels.
Serotonin plays a role in?
 depression
 OCD
 Impulsive disorders
 Affect (Emotion)
 Eating and drinking
 Arousal (Both Alertedness and Sleepiness)
Histamines have to do mostly with ____.
Allergies.
Mast Cells:
Cells that release Histamine.
What does Histamine do to body?
* Dilates Capillaries
* Causes flaring of wounds.
What does Histamine play a role in?
• Arousal
• Eating or drinking
• Pain
Amino Acids and their roles
The roles they play
GABA Plays a role in:
• Arousal
• Epilepsy
• Estrogen levels
Glycine: (Mostly _Inhibitory_) Plays a role in...
• Anorexia
• Sleep
Glutamate- major _Excitatory_ NT in your brain, Plays role in:
• Especially important in Learning and Memory.
• Visual Development
• Conductor of _Mild_ pain
• Arousal
• Disorders
• Addiction
What is Glutamates particular receptor?
NMDA
Why is Glutamate crucial in learning?
It increases New Synapses.

With NMDA, if there’s an increase in Glutamate, then there’s an increase in Calcium which increases Dendrite Bunches and New Synapses.
Too much Glutamate kills _____ and can lead to ________.
* neurons
* Amnesia
Aspartate is chemically similar to _____.
Glutamate.
Highest amount of Aspartate found in the _______.
_Thalamus_(The Switchboard)