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149 Cards in this Set
- Front
- Back
What are the 5 viewpoints of biological psychology?
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1) Description of behavior, 2) its evolution, 3) its lifetime development, 4) its underlying biological mechanisms, and 5) applications of knowledge to dysfunctional behavior
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What are the three approaches to understanding the brain-behavior link?
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1) somatic intervention: alter a structure or function of the brain or body
2) behavioral intervention: change an organism's behavior, examine for changes in bio 3) correlation: finding the extent to which a bio measure corresponds with a behavior measure |
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Basic unit of the nervous system is:
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Neuron
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The hypothesis that the brain is composed of separate cells that are structurally, metabolically, and functionally distinct:
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Neuron doctrine
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Researcher who showed that neurons are not CONTINUOUS, but rather CONTIGUOUS:
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Ramon y Cajal
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Non-neural brain cells that provide structural, nutritional, and other support to the brain:
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Glial cells, neuroglia
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Structures in cell body where genetic info is translated to produce proteins:
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Ribosomes
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Extensions of neuron cell bodies that are the receptive surfaces:
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dendrites
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Area of neuron receiving info from other neurons or specialized sensory structures, corresponding to dendrites:
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Input Zone
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Cell body region
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soma (pl. somata)
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Area of neuron cell body where signals are combined and transformed:
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Integration Zone
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Area corresponding with axon, leading away from cell body and towards axon terminals:
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Conduction Zone
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Area corresponding to axon terminals, where cell's activity is communicated to others:
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Output Zone
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1/10 of a centimeter
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millimeter
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1/1000 of a millimeter
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micrometer
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histological stain that fills a small number of neurons with dark, silver-based dye
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Golgi stain
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histological stain outlining all cell bodies via attraction of dye to RNA in nuclei; helps measure cell body size and cell density of regions:
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Nissl stain
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histological technique showing the distribution of radioactive chemicals in tissues, enabling researchers to know (for example) what parts of the brain are affected by a drug
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autoradiography
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method of detecting types of proteins in tissues, using manufactured antibodies that attach to target proteins and are then chemically treated to be made visible
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immunocytochemistry (ICC)
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method for detecting specific RNA transcripts in tissue by using radioactively-labelled bits of nucleic acid that will bind with the targeted RNA
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in situ hybridization
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class of genes showing rapid, temporary increases in expression in activated cells
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immediate early genes (IEGs)
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common example of an IEG
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c-fos
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enzyme found in a particular plant's roots which is useful for determining cells of origin for a particular set of axons, by being taken up at axon terminals and traveling backward
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horseradish peroxidase (HRP)
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3 principal types of neurons:
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1) multi-polar
2) bipolar 3) unipolar/monopolar |
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many dendrites, single axon, most common type of neuron:
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multi-polar
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single process/extension, branching in two directions from cell body, one toward dendrites, one toward axon terminals; e.g. those transmitting touch info from body into spinal cord:
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unipolar/monopolar neurons
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single dendrite, single axon, common in sensory systems like vision:
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bipolar neurons
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nerve cell transmitting motor messages that stimulate a muscle or gland:
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motoneuron
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neuron directly affected by changes in environment:
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sensory neuron
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neuron that receives input from and sends output to other neurons; vast majority of neurons
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interneurons
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major types of glial cells:
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1)astrocytes
2) microglial cells 3)oligodendrocytes 4)Scwhann cells |
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star-shaped glial cell with numerous processes running in all directions, often regulating bloodflow and monitoring nearby synaptic activity:
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astrocyte
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extremely small glial cells that clean up cellular debris and protect injured cell sites
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microglial cells
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glial cell that forms myelin in the Central Nervous System (brain & spinal cord):
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oligodendrocyte
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fatty insulation that coats conduction zones of neurons, formed by glial cells, and improving speed of conduction:
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myelin
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gap between a pair of myelinated axonal segments where axonal membrane is exposed:
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node of Ranvier
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demyelinating disease (lit. "many scars") that can have catastrophic results:
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multiple sclerosis
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glial cell providing myelin in the peripheral nervous system (everything outside brain, spinal cord):
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Schwann cell
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swelling of injured tissue, e.g. glial cells in brain, that can compound brain injuries:
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edema
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elaborate branching of some dendrites:
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arborization
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referring to region of synapse releasing neurotransmitters:
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presynaptic
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referring to region of synapse receiving and responding to neurotransmitters:
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postsynaptic
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specialized membrane of axon terminal of transmitting neuron; releases neurotransmitters:
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presynaptic membrane
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space between presynaptic and postsynaptic regions:
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synaptic cleft
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small spherical structure containing molecules of neurotransmitter, which fuses with presynaptic membrane in response to neuronal electrical activity:
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synaptic vesicle
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specialized protein molecule on postsynaptic membrane that captures and reacts to neurotransmitters:
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receptors
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common number of synaptic contacts on a neuron:
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5,000-10,000
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average synapse size:
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less than a square micrometer
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cone shaped area from which the axon protrudes from the cell body, functionally corresponding to the "integration zone":
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axon hillock
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a branch of the same axon from a neuron:
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axon collateral
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to provide neural input; to make synaptic contact with another cell:
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innervate
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movement of material (proteins, recycled materials) within the neuron, to and from cell body:
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axonal transport
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visible demarcations of the nervous system, e.g. CNS/PNS, cerebral hemispheres)
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gross neuroanatomy
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three component nerve-groupings that make up the Peripheral Nervous System:
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1) cranial nerves
2) spinal nerves 3) autonomic nervous system |
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collection of axons bundled together outside CNS:
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nerve
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regulatory system primarily controlling the glands and smooth muscles of the viscera
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autonomic nervous system
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12 pairs (I-XII) of cranial nerves that serve sensory and motor systems in head and neck
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I. Olfactory
II. Optic III. Oculomotor IV. Trochlear V. Trigeminal VI. Abducens VII. Facial VIII. Vestibulocochlear IX. Glossopharyngeal X. Vagus XI. Spinal accessory XII. Hypoglossal |
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3 cranial nerves that are exclusively sensory pathways to the brain:
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olfactory (I), optic (II), and vestibulocochlear (VIII)
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5 cranial nerves that are exclusively motor pathways from the brain:
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oculomotor (III), trochlear (IV), abducens (VI), spinal accessory (XI), & hypoglossal (XII)
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4 cranial nerves that have both motor and sensory functions (on separate axons, of course):
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trigeminal (V), facial (VII), glossopharyngeal (IX), & vagus (X)
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how many pairs of spinal nerves?
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31 (one member of each pair to a side of the body)
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spinal nerves are also known as:
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somatic nerves
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each spinal nerve is made by the fusion of two branches, called "roots", respectively known as:
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dorsal & ventral roots
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branch of a spinal nerve that carries sensory info from the PNS to the spinal cord:
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dorsal root
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branch of a spinal nerve that carries motor messages from the spinal cord to the PNS:
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ventral root
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general name and number of membranes surrounding spinal cord and brain:
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3 meninges
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each layer of meninges, from outer to inner:
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dura mater, arachnoid, pia mater
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names of spinal cord regions, and the number of spinal cord segments (and attached pairs of nerves) in each:
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cervical: 8
thoracic: 12 lumbar: 5 sacral: 5 coccygeal: 1 |
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component of the autonomic nervous system that arises from the thoracic and lumbar regions of the spinal cord:
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sympathetic nervous system
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component of the autonomic nervous system arising from "above" and "below" the sympathetic, i.e. from cranial nerves and the sacral spinal cord
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parasympathetic nervous system
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two general types of nerves in both the sympathetic an parasympathetic divisions of the autonomic nervous system:
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preganglionic and postganglionic
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collections of nerve cell bodies found in various locations, and innervating major organs:
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autonomic ganglia
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chain of ganglia on each side of spinal column:
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sympathetic chain
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local network of sensory and motor neurons that regulate digestion, resembling a mesh, controlled by CNS:
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enteric nervous system
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neurotransmitter produced and released by sympathetic postganglionic neurons to accelerate organ activity; also produced in brain-stem and found throughout the brain:
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norepinephrine/noradrenaline
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neurotransmitter produced & released by parasympathetic postganglionic neurons, motoneurons, and various neurons in the brain to slow down various organic processes:
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acetylcholine
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executive portion of the CNS:
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brain, i.e. cerebrum
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ridges of tissue formed by external folding of brain tissue:
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gyri
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troughs or furrows between the ridges of tissue formed by folded brain tissue:
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sulci
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the 4 sectors of the cerebral hemispheres:
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frontal, parietal, temporal, and occipital lobes
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C-shaped bundle of axons allowing communication between the cerebral hemispheres:
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corpus callosum
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deep fissure demarcating the temporal lobe from the frontal and parietal lobes; also known as the lateral sulcus:
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Sylvian fissure
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fissure dividing the frontal and parietal lobes:
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central sulcus
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strip of frontal cortex, just in front of the central sulcus, that is crucial for motor control:
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precentral gyrus
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strip of parietal cortex, just behind the central sulcus, that mediates the sense of touch:
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postcentral gyrus
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areas/layers of brain and other nervous tissue that is dominated by cell bodies:
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gray matter
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areas/layers of brain and other nervous tissue dominated by axon fibers with myelin sheathing:
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white matter
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three planar orientations for viewing brain and body:
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horizontal (top and bottom), sagittal (left side and right side), and coronal or transverse (front and back)
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anterior (e.g. a ship's prow)
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rostral
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posterior (e.g. tail)
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caudal
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toward the middle
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medial
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toward the side
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lateral
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referencing a 2nd location on the same side as the first location
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ipsilateral
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referencing a 2nd location on the opposite side as the first
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contralateral
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near vs. distant
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proximal vs. distal
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an axon, tract, or nerve carrying info INTO a region of interest is:
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afferent
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an axon, tract or nerve carrying info AWAY from a region of interest:
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efferent
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embryonic CNS, with divisions corresponding to the future forebrain, midbrain, and hindbrain:
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neural tube
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forebrain
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prosencephalon
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midbrain
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mesencephalon
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hindbrain
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rhombencephalon
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frontal subdivision of the prosencephalon, containing the cerebral hemispheres:
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telencephalon
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what is contained in the cerebral hemispheres:
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cortex+basal ganglia+limbic systems
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posterior part of the prosencephalon, containing the thalamus & hypothalamus:
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diencephalon
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divisions of the rhombencephalon:
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metencephalon & myelencephalon
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what does the metencephalon contain?
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cerebellum + pons
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what is the myelencephalon more often known as?
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medulla
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what is contained in the "brainstem"?
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midbrain, pons, & medulla
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aggregation of neurons in a given region of the brain:
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nuclei
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bundles of axons in regions of brain:
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tracts
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the basal ganglia are composed of:
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1) caudate nucleus, 2) globus pallidus, 3) putamen, 4) subthalamic nucleus, and 5) substantia nigra
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loosely-defined, widespread network of structures involved in emotion and learning:
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limbic system
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the limbic system includes:
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1) amygdala, 2) hippocampus, 3) fornix, 4) cingulate gyrus, 5) olfactory bulb, 6) hypothalamus, and 7) mammilary bodies
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complex cluster of nuclei acting as a way station to the cerebral cortex:
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thalamus
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paired gray matter structures on the dorsal surface of the midbrain, involved in visual attention:
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superior colliculi
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paired gray matter structures on the dorsal surface of the midbrain, involved in auditory reception:
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inferior colliculi
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dorsal region of the midbrain, including both pairs of colliculi:
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tectum
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a part of the basal ganglia located in the midbrain, containing neurons that release dopamine:
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substantia nigra
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motor center in the midbrain that communicates with motoneurons in the spinal cord:
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red nucleus
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a network extending from the medulla to the thalamus, implicated in sleep and arousal functions:
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reticular formation
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large neurons composing the middle layer of the cerebellum's folds:
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Purkinje cells
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small nerve cells in the bottom layer of the cerebellum's folds:
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granule cells
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axons from the granule cells that compose the outer layer of the cerebellum:
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parallel fibers
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immediately ventral to the cerebellum:
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pons
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cortical tissue with three layers or unlayered organization:
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allocortex
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# of distinct cortical layers:
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6
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distinction of cortical layer I:
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few cell bodies
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distinction of cortical layers V and VI:
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many neurons with large cell bodies
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large nerve cell that is prominent in the cortex, esp. layers III and V:
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pyramidal cells
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extension of pyramidal cells that reaches the outermost layer of cortex:
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apical dendrites
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dendrites that spread out horizontally from pyramidal cells:
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basal dendrites
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info-processing units perpendicular to cortical layers, extending from white matter below to the gray surface above:
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cortical columns
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series of chambers filled with CSF (cerebrospinal fluid) in the center of the brain:
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ventricular system
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specialized membrane lining the inside of the lateral ventricles, and secreting CSF:
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choroid plexus
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arteries arising from the carotids, that provide blood to the anterior poles and medial surfaces of the cerebral hemispheres:
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anterior cerebral arteries
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arteries arising from the carotids, providing blood to the lateral surfaces of the cerebral hemispheres:
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middle cerebral arteries
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arteries that ascend the vertebrae and enter the base of the skull:
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vertebral arteries
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artery formed by the fusion the vertebral arteries, providing blood to the brainstem and the posterior cerebral arteries:
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basilar artery
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arteries arising from the basilar, providing blood to the posterior aspects of the cerebral hemispheres, the cerebellum and the brainstem:
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posterior cerebral arteries
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structure at the base of the brain (rostral to the brainstem) formed by the major cerebral arteries:
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circle of Willis
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brain-imaging wherein cerebral blood vessels are injected with a dye and then x-rayed to aid in the diagnosis of vascular disease:
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angiography
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computer analysis of brain structure using x-ray absorption at multiple positions around the head:
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computerized axial tomography
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technique to study brain structure, using magnetic energy to line up proteins in water molecules in the brain, then knocking them over with a blast of radio waves, then detecting micro-emissions of radio waves as the protons realign:
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magnetic resonance imaging
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technique to examine brain region function, using radioactive tracers (often attached to glucose) and multiple-position detectors:
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positron emission tomography
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technique to study brain region function with rapidly oscillating magnetic fields that detect oxygen availability:
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functional MRI
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use of reflected near-infrared light to reveal the activity of cortical regions:
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optical imaging
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use of focal magnetic currents to briefly stimulate the cortex, allowing mapping of the resulting patterns of activation through OI:
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transcranial magnetic stimulation
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detectors used to sense changes in magnetic fields created by neuronal activity:
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Superconducting Quantum Interference Devices
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method that uses SQUIDS to create realtime maps of brain activity from localized cortical magnetic fields:
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magnetoencephalography:
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