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5 Cards in this Set

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What is Ghrelin?
It is secreted primarily by the stomach and it appears to play an important role in the central control of food intake.
It also stimulates GH secretion by acting directly on receptors in the pituitary.
What is GIP?
It has 42 amino acids, and is produced by K cells in the mucosa of the duodenum and jejunum.
What stimulates its secretion?
It is stimulated by glucose and fat in the duodenum and because in large doses it inhibits gastric secretion and motility.
Does GIP stimulate insulin secretion?
Yes. Gastrin, CCK, secretin and glucagon als have this effect, but GIP is the only one that stimulates insulin secretion when administered in doses that produce blood levels comparable to those produced by oral glucose.
Is GIP also called glucose dependent insulinotropic polypeptide?
Yes.