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33 Cards in this Set
- Front
- Back
Laplaces Law equation? interpretation?
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2T/r
As you increase radius you dilute surfactant so that T and r increase together. This keeps pressure in the airways equal and prevents collapse of small --> large |
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Minute ventilation equation?
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VE = f*Vd + f*Va
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PECO2?
PACO2 |
PECO2 = mixed expired air = measured at the mouth
PACO2 = alveolar CO2 |
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Fraction of tital volume that is physiological deadspace
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VD/VT = PACO2 - PECO2/PACO2
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Henry's Law
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Cx = Px*Sx
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Alveolar ventilation equation?
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VA = VCO2 [(PB-47)/PACO2]
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Respiratory quotient?
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VCO2/VO2
normally 0.8 |
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PAO2 equation?
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PAO2 = PIO2 - [PACO2/R]
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% saturation of hgB?
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O2bound /O2 capacity
O2 capacity hgb = 15g/dL * 1.34mL O2/gm |
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% saturation?
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total O2 content - dissolved O2/O2capacity
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concentration of disolved O2?
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0.3 mL O2/dL
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FEV1/FVC
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normally 80%
low values suggest obstruction or lack of driving pressure |
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Changes in Fibrosis or scoliosis:
FVC FEV1 FEV1/FVC |
FVC = <80%
FEV1 = reduced FEV1/FVC = normal |
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Changes in obstruction:
FVC FEV1 FEV1/FVC |
FVC = normal or reduced
FEV1 = reduced <80% FEV1/FVC = reduced <70% |
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How to convert PAO2 to [O2] dissolved?
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[O2] = PA02 · 0.003
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Bicarb buffer equation?
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pH = 6.1 + log [HCO3- ] / 0.03 PCO2
0.03 is in mMoles/L/mmHg HCO3 is in mMoles |
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Normal values:
RBF = ? RPF = ? GFR = ? |
RBF = 1 L blood/min
RPF = 0.6RBF = 600ml/min GFR = 0.2 RPF = 125 ml/min |
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Ex =? (2 equations; general and physiological)
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Ex = Fx + Sx - Rx
Ex = Ux * V |
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Fx =?
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Px * GFR
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Cx = ?
Cx of inulin? Cx of PAH? |
Cx = (Ux * V)/Px
Cx of inulin = GFR b/c all inulin is filtered and excreted with no secretion or reabsorbtion Cx of PAH = RPF |
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calculate RBF using HCT
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RBF = RPF * (1/1-Hct)
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FF =?
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GFR/RPF
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Rate of reabsorbtion?
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reabsorbed = filtered - excreted
Rx = (Px * GFR) - (Ux * V) |
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Percentage of a filtered solute reabsorbed?
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= rate of reabsorbtion/rate of filtration
(Px * GFR) - (Ux * V)/(Px*GFR) |
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relationship between plasma creatnine and GFR?
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if Pcreat increases GFR is decreased
If Pcreat decreases GFR is increased |
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%H20 reabsorbed using Ux and Px?
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%H2O = 1 - 1/(U/P)
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a drop of ______ pH unit will result in an average increase of _______ mEq/L in plasma K
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a drop of 0.1 pH unit will result in an average increase of 0.6 mEq/L in plasma K
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Free water clearance equations
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CH20 = V - Cosm
CH2O = V[1-U/P] |
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Positive CH2O?
Negative CH2O? |
Positive = water is excreted
Negative = water is reabsorbed |
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Acid base equation
pH = ? |
pH = 6.1 + log [HCO3]/0.03pCO2
pH = 6.1 + log [HCO3- ] / 0.03 PCO2 0.03 is in mMoles/L/mmHg HCO3 is in mMoles |
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NAE = ?
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Net Acid Excretion
NAE = Utitration + UNH4+ - UHCO3 |
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anion gap
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anion gap = [Na] - ([Cl] + [HCO3])
normal = 5-11 |
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Acids that increase anion gap?
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lactic acid or ketoacid
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