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90 Cards in this Set

  • Front
  • Back
why something happens & what's the big picture
teleological approach to physiology
how something happens
mechanic approach to physiology
mediates exchange of materials btwn cells and environment
ECF
the ability of the body to maintain a relatively constant internal environment
homestasis
- it is DYNAMIC
what are some examples of parameters that homeostasis is in control of
- environmental (temperature, pH)
- materials cell needs (nutrients, water, Na, Ca, ions)
- internal secretions (hormones)
3 cavities of body
1. cranial
2. thoracic
3. abdominal
- organismal level of compartmentation
signalling molecule released in bloodstream & acts on target cells in distance
hormone
neurocrine released by neuron into blood & acts on distant target cells
neurohormones
acts more slowly than NTs & act in autocrine & paracrine signals
neuromodulator
chemical signal secreted by neuron
neurocrine
cannon's postulates are:
1. nervous system has a role in preserving the fitness of internal environment
2. some systems of body are under tonic control
3. some systems of body are under antagonistic control
4. 1 chemical signal can have different effects in diff tissues
control that can be varied up or down by same effector
tonic control
ex) volume on ipod
type of control where 2 regulators w/ opposite effects on same variable
antagonistic control
3x) heating & air
paracrine & autocrine are ___ control
local
nervous & endocrine is __ control
reflex
- long distances
the ___ ___ evaluates signal & compares it to a set point & initiates response
integrating center
a change in a regulated variable
stimulus
___ monitors the variable& sends info to integrating center
sensor/ receptor
true or false- endocrine signals last longer than nervous system
true
in endocrine signalling the efferent signalling is a
hormone
neuroendocrine reflexes have how many integrating centers?
2 or more
these are classified chemically as peptides, steroids, or amines
hormones
__ hormones bind to membrane receptors
peptide
__ hormones are derived from cholesterol
steroid
steroid hormones in adrenal cortex are
cortisol & aldosterone
steroid hormone in ovary
estradiol
___ hormones bind to cytoplasmic receptors
steroid
- most are bound to steroid plasma protein carriers
- receptors are in cytoplasm or nucleus
what are 3 catecholamine hormones
1. dopamine
2. norepinephrine
3. epinephrine
what is an example of a thyroid hormone
1. thyroxine
__ is an amine hormone derived from the amino acid tryptophan
melatonin
what are the 2 tyrosine derivative hormones
1. catecholamines
2. thyroid hormones
___ pituitary is an extension of the neural tissue
posterior
___ pituitary is a true endrocrine gland of epithelial origin
anterior
– controls ejection of milk during breastfeeding
– Stimulates uterine contractions during labor
– other possible modulatory functions in the brain
oxytocin
- posterior pituitary
– regulates water balance (promotes water reabsorption)
– Target tissue is kidney
– also called antidiuretic hormone (ADH)
vasopressin
- posterior pituitary
every anterior pituitary hormone is a trophic hormone except for ___
prolactin
the hypothalamic-hypophyseal portal system is used for what hormones
anterior pituitary
-
The combination of
hormones produces a
result that is greater
than additive.
synergism
One hormone cannot fully exert its effects unless a
second hormone is present is called
permissiveness
2 parts of periphral nervous system:
afferent & efferent
2 parts of efferent nervous system
autonomic (smooth muscle, cardiac muscle, somatic (skeletal muscle)
CNS is made of
brain & spinal cord
2 parts of autonomic system
1. parasympathetic
2. sympathetic
- many shared targets usually antagonistic
functional unit of the nervous system
neuron
space between axon terminal and target cell
synaptic cleft
__ neurons are afferent neurons
sensory
- pseudounipolar & bipolar
___ neurons are in the CNS
interneurons
__ neurons go from CNS to effectors
efferent
- ex) motor
__ nerves are both sensory & motor axons
mixed
cluster of nerve cell bodies in the PNS
ganglion
cluster of nerve cell bodies in CNS
nucleus
neurocrines are __ from axon terminal & ___ in cell body
secreted; synthesized
true or false- glial cells are only used for support cells
true
50% of all cells in brain are ___
astrocytes
what kind of cells form the myelin sheath
schwann cells, oligodendrocytes
the net amount of electrical charge produced by any process is 0
law of conservation of electrical charge
material that allows separated positive & negative charges to move freely toward each other
conductor
- ex) water, cytoplasm
material that prevents separated charges from moving toward each other
insulator
ex) phospholipid bilayer
flow of electrical charge carried by
an ion
current
The direction of ion movement depends on
the ___ ___ for the ion.
electrochemical gradient
amplitude (strength) is variable & depends on strength of initial stimulus
• Small stimulus creates small graded potential
• Voltage change may be in either direction- depolarizing or hyperpolarizing
• Usually ions involved: Na+, Cl-, and Ca2+
graded potential
true or false- graded potentials can add up
true
- can also be inhibitory
– A second action potential cannot be triggered regardless of
the strength of the stimulus
– Basis: time required for Na+ channel gates to reset
– Implications: Action potentials cannot overlap and cannot
travel backward.
absolute refractory period
– A stronger than normal depolarizing graded potential is
required to reach threshold and trigger an action potential,
which may be smaller than normal
– Basis: some (but not all) Na+ channels have reset, K+
channels are still open
relative refractory period
• Autoimmune disease –more common in women
• Antibodies destroy myelin sheath around neurons in CNS
• So K+ leaks out of cell through voltage-gated K+ channels- causes cells to become hyperpolarized (cell will require bigger potential to reach AP)
• Symptoms: muscle weakness, fatigue, decrease in coordination, paralyzed
• No cure
MS
• Demyelinating autoimmune disease
• Affects sensory & motor neurons in PNS
• Very rapid onset – can be paralyzed within a weak
• Can recover from it
Guillain-Barre Syndrome
axon terminal of neuron sending the signal
presynaptic cell
bind to NT and initiate some sort of response
postsynaptic cell
__ is made from acetyl-CoA & choline
acetylcholine
acetylcholine has 2 types of cholinergic receptors:
nicotinic & muscarinic
True or false- Norepinephrine (NE)- can be used as a NT, epinephrine cannot
true, it can only be used as a neurohormone
one controlling neuron coordinating a response is called
divergence
when a neuron receives info from multiple pre-synaptic cells when they converge on 1 post-synaptic cells
convergence
layer of meninges thick protective layer associated w/ veins that collect blood from brain through sinuses
duramater
true or false- In most regions, blood is kept separate from
neural tissue by the blood-brain barrier
true
____ fluid is inside the pia mater
Interstitial
___ is in ventricles and subarachnoid space
CSF
spinal cord divided into 2 areas-
white matter & gray matter
__ matter in spinal cord is unmyelinated & contains interneurons
gray
__ matter in spinal cord is myelinated & runs to/from the brain & between different parts of spinal cord
white
a __ reflex initiates a response w/o input from the brain
spinal reflex
___ is in charge of involuntary
functions (e.g., blood pressure,
breathing, swallowing, vomiting
medulla oblongata
___ is in charge of information relay point between
cerebrum and cerebellum; control of
breathing
pons
___ is in charge of eye movement
midbrain
__ is in charge of sleep/arousal, muscle tone, breathing, BP, pain
reticular formation
rest and digest is what branch of autonomic division
parasympathetic
fight or flight is what branch of autonomic division
sympathetic
major areas of limbic system:
amygdala, cingulate gyrus, hippocampus
amygdala & cingulate gyrus are linked to:
emotion & memory
hippocampus is associated with:
learning & memory