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67 Cards in this Set

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  • Back

ions and proteins, systems


integration of anatomy, biology, chem, and physics

what is physio?


ATP <---> ADP + Pi + energy



Glucose +O2 + ADP + Pi ---> ATP + CO2 +H20 + heat



CO2 + H20 <---> HCO3- + H+



PV=NRT

4 critical equations in physio


our currency to spend and to accomplish various processes

ATP <---> ADP + Pi + energy


what is this used for

use this equation to make the most currency for our body

glycolysis


glucose + O2 + ADP + Pi ----> ATP + Co2 + H2O + Heat

this aids in the transport of a key gas (equation)


but creates a pH problem...

CO2 + H2O <-----> HCO3- + H+

this eq is key in the lungs, blood vessels, etc

PV=NRT

glucose

this spikes after a meal

homeostasis

creates stable maintenance in the body


same as dynamic constancy

homeotostatic control systems

hormones and cells and systems make sure the parameters stay relatively the same


set of interconnected components

keep parameter at its set point (SP)

purpose of homeostatic control systems

set point

range of normal functioning in the body

steady state

parameter at its SP


systems not changing, but energy being used to keep in the range


NOT at equilibrium, no chage in energy at eq.


because energy limites, trade off required to keep one parameter at _____ or another

disturbances from steady state

reactive---> response = feedback


negative = opposite of ___ direction


positive = continue in same direction of _______

feed-forward feedback

an anticipation in a disturbance from steady state


body doesn't have to react as much


limits the degree of feedback that's necessary


less energy required

biorhythms

homeostatic control systems (HCS)


24 hour cycle patterns, circadian, annual, lunar


all patterns not the same


ex body temp higher when sleeping


plasma growth hormones higher when sleeping



feedforward

type of activation seen in biorhythms


proactive instead of reactive

DNA

we are set up to be active during the day and sleep at night (diurnal) in our _______

internal clocks

internal trigger components that tell us what time it is and whether we should be active or inactive


NOT determined by the environment

genetic changes

adaptations that set us up for survival come from ______


adapted to have biorhythms set up and ______ made us that way

acclimatization

-the adjustments we can make to biorhythms (within limits) to our biorhythms


-ie clock reset, changing SP

clock reset/SP changes

-this happens due to the environment


-but NOT based on genetic changes


-usually reversible


-exception: fetal ______ in development (eg fetal alcohol syndrome)


-any changes in utero cannot be reversed

reflex arc

-a control for HCS


-way to control a system using circular pathway of afferent and efferent pathways

receptor

-part of reflex arc


- first part of the arc that receives a stimulus


can be external or internal


-

afferent pathway

-part of reflex arc that goes to something


-goes to integrating center

integrating center

-part of reflex arc that knows what the current set point is and if we are in it or not


-can be brain, glands, etc


-if in correct range nothing happens


-if we are off our SP, we need to do something to change it


-

efferent pathway

-part of reflex arc


-going from something


-going to place in the body that is going to create a change


-get response (whatever change we need in physiology to counteract a stimulus)


-change happens by messages being passed

glands or neurons

endocrine cells released by __________

chemical messengers

move through EC fluid to elecit a response


-3 types: endocrine, paracrine, neurotransmitter

plasma (water portion of the blood)

pathway for endocrine messenger

distant effectors

endocrine messengers communicate with ______

distant effectors

any cell that has interaction potential with blood (pretty much every cell)

most cells

cells that release paracrine messengers

interstitial fluid (IF)

pathway for paracrine messengers

neighbor effectors (bc moves by diffusion, can't diffuse under a long range)

paracrine messengers communicate with ______

neurons

cells that release ntrans

IF (synapse)

pathway for ntrans

next neighbor neuron or effector

ntrans communicate with _____

autocrine, cytokines

three other chemical messengers that you cannot group in with the main 3


-still travel thru EC fluid

autocrine

chem messengers that communicate with itself


-effector is releaser


-pathway is IF

cytokine

-chem messenger


-pathway thru IF/plasma/lymph


juxtacrines and gap junctions

chemical messengers that are not based on EC fluid


gap junctions

direct channels between adjacent cells


-signal present in one cell and can move thru and be a signal in another cell

juxtacrines

messengers bound to the cell membrane


not released, stays on the surface

cell

basic unit of body organization


-all contain the same DNA


-new ____ via mitosis

differentiation

cells go from unspecialized to specialized

muscle, connective, nerve, epithelial

4 major categories of cells

muscle cells

cells that help generate mechanical force (move, beat heart etc)

nerve cells

these cells works to make electrical signals

epithelial cells

these cells interact with the outside environment


ie, skin, lungs

connective cells

cells that connect,anchor, and support


ie metabolic, structural, etc

muscle, connective, nerve, epithelial

four major types of tissues

tissues

groupings of similar specialized cells

organs

combinations of tissues


-vary in proportion and pattern

functional unit

does the whole job of the organ but is repeated over and over


-whole organ is duplications of the ________ to do the larger function


-nephron is the _______ of the kidney


-not every one is working all the time

redundancy

don't lose the function of the organ just because one functional unit isn't working

expansion

can expand the capacity of an organ and not lose any time


-add more without stopping

heart

only has one functional unit

organ systems

organs with a common function


-many contain organs from other ______


ex: immune = WBCs, spleen, thymus and WBCs are in circ

matrix

-mix of proteins and minerals


-function is to provide structure and regulate info transfer

protein types in the matrix

fibers, main ones (eg hair) long and thin


-collagen and elastin and reticular

collagen

fiber in the body with rope-like traits

elastin

fiber in the body, rubber band like trait

reticular fibers

fibers in the body


type III collagen


form a scaffolding for other cells

intracellular, extracellular, plasma

3 fluid compartments

intracellular fluid

-type of fluid compartment


-cytosol within the cells


-67% of total water

extracellular fluid

-type of fluid compartment


-outside of the cells


-interstitial fluid (IF) - between cells


26% of total water



plasma

-type of fluid compartment


-7% of total water