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15 Cards in this Set
- Front
- Back
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Common manifestations of vitamin D deficiency are
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symmetric low back pain, proximal muscle weakness, muscle aches, and throbbing bone pain elicited with pressure over the sternum or tibia.
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What test should be obtained in patients with suspected vitamin D deficiency.
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25-hydroxyvitamin D
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What are the levels for 25-hydroxyvitamin D deficiency or insufficiency
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Deficiency is defined as a serum 25-hydroxyvitamin D level of less than 20 ng per mL (50 nmol per L), and insufficiency is defined as a serum 25-hydroxyvitamin D level of 20 to 30 ng per mL (50 to 75 nmol per L).
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In persons with vitamin D deficiency, treatment may include oral ergocalciferol (vitamin D2) at what dose?
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50,000 IU per week for eight weeks.
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What is a maintenance dose of cholecalciferol (vitamin D3) once deficiency has been corrected?
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800 IU per day
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What are the two forms of vitamin D:
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1. vitamin D2 (ergocalciferol), which comes from irradiation of the yeast and plant sterol (cholecalciferol), ergosterol
2. vitamin D3 which is obtained from oily fish and by skin synthesis. |
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What percent of vitamin D is from sun synthesis?
What percent of vitamin D is from dietary sources? |
90 percent of vitamin D from sunlight.
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What percentage of patients may fail to maintain healthy bone density and tooth attachment because of inadequate vitamin D levels.
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50 percent of persons 65 years and older in North America and 66 percent of persons internationally (all ages)
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Risk factors for vitamin D deficiency
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anticonvulsants or glucocorticoids,
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What are the sources of D3?
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Dietary D2 or D3
Skin UV radiation of dehydrocholesterol |
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Previtamin D3 is with OH from the liver yields?
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25- hydroxyvitamin D
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25- hydroxyvitamin D plus OH from the kidney yields?
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1,25- hydroxyvitamin D (activated )
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Kidney activates vitamin D based on
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Increased PTH or decreased phosphorus
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The Endocrine Society recommends that adults who are deficient in vitamin D be prescribed:
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receive 50,000 IU of ergocalciferol or cholecalciferol weekly for eight weeks, based on a study of 38 patients who received ergocalciferol.10
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When does the vitamin D level peak after vitamin is supplemented?
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An RCT of 61 men and women 32 to 50 years of age who were randomized to 1,000 IU or 4,000 IU of vitamin D daily found that levels peaked at three months, regardless of dosage
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