Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
Indications of Phenothiazines?
|
Used peri-anesthetically to reduce anxiety, induction & maintenance drug doses, contribute to balanced anesthesia.
Administer along with Opiods for synergistic effect. Anti-emetic. Some anti-histamine effect. |
|
|
Indications of Injectable Anesthetics?
|
Sedation/hypnosis/anesthesia
|
|
|
Drug choices of Phenothiazines?
Common root? |
Acepromazine.
Chlorpromazine. Fluphenazine. "-azine" |
|
|
Drug choices of Injectable Anesthetics?"
Common root? |
Propofol.
Etomidate Guaifenesin. None. |
|
|
Uses and MOA of Acepromazine?
|
Phenothiazine.
Antagonizes stimulation from dopamine in the CNS. Sedation and anti-emetic (via D2 & alpha-adrenergic CRTZ). |
|
|
Uses and MOA of Chlorpromazine?
|
Phenothiazine.
Better anti-emetic than ACE. Sedation. |
|
|
Adverse effects of Acepromazine and Chlorpromazine?
|
Altered involuntary motor activity.
Peripheral alpha-adrenergic blocking = vasodialation. Penile prolapse in stallions. |
|
|
Contraindications of Acepromazine, Chlorpromazine, and Fluphenazine?
|
Not allowed in race horses or show horses.
No ACE in Boxers. |
|
|
Uses and MOA of Propofol?
Adverse effects? |
Enhances the effects of GABA. Causes CNS depression.
Not analgesic. Increases intracranial pressure, decreases intraoccular pressure. Respiratory depression and muscle relaxation. Low therapeutic index. Limited shelf-life. |
|
|
Uses and MOA of Etomidate?
Adverse effects? |
GABA agonist --> Creates CNS depression.
No specific binding site. No muscle relaxation and not analgesic. Decreases intraoccular and intracranial pressure. Minimal cardiovascular effects. |
|
|
Metabolism of Injectable Anesthetics?
|
Redistributed from CNS to body tissues then metabolized by liver. Do not alter dose based on BCS.
|
|
|
Uses and MOA of Guaifenesin?
Adverse effects? |
Specific mechanism unknown. Inhibits neurons in the brain by depressing nerve transmission --> CNS sedation. Muscle relaxation. No cardiovascular or respiratory effects.
Not analgesic.1 |
