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50 Cards in this Set
- Front
- Back
Metronidazole (Flagyl) is useful to treat?
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Periodontal anaerobes
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Cephalexin, Keflex, Ceclor
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Types of Cephalosporins
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antibiotic with actions similar to penicillins, inhibits cell wall synthesis
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Cephalosporins
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How are Cephalosporins administered?
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orally,IM, IV
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A wide spectrum against organisms involved with oral infections esp. anaeorobes
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Cephalosporins
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What's the half-life for cephalosporins?
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1 hr. to 6 hrs.
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Where are cephalosporins metabolized?
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Metabolized in the liver and excreted in urine
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What are the adverse effects for cephalosporins?
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GI
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Other effects of cephalosporins?
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superinfection, cross-hypersensitivity with penicillins, renal toxicity
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What are cephalosporins useful for?
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Infections by microbes resistant to penicillins
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*Isoniazid
*Rifampin *Pyrazinamide *Ethambutol |
Antituberculosis Agents
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*bactericidal only aganist actively proliferating organism, disrupts cell wall
*taken for 9-12 months *used alone as a prophalytic agent to those recently exposed to Tb or seroconverts |
Isoniazid
(Antituberculosis Agent) |
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*Bactericiostatic antibiotic that inhibits DNA and RNA enzymes
*taken for 9-12 months |
Rifampin
(Antituberculosis Agent) |
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*bactericidal
*usually used for the first 2 months or until negative sputum samples |
Pyrazinamide
(Antituberculosis Agent) |
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*bacteriostatic agent
*used if other agents cannot be used |
Ethambutol
(Antituberculosis Agent) |
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*used for prevention of bacterial endocarditis
*used when possibility of introducing significant bacteremias *based upon American Heart Association recommendations *also used in prostheic joint replacements *primary and speciality physicians should be consulted |
Antiboitic PreMedication
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*Nystatin
*Imidazoles *Amphotericin B and Griseofulvin |
Antifungal Agents
|
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Mycostatin, Lamisil, Nizoral
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Nystatin
(Antifungal Agents) |
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fungicidal and fungistatic antiboitic by altering cell wall permeability
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Nystatin
(Antifungal Agents) |
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*poorly aborsorbed through mucosa,skin, or GI
*few adverse effects |
Nystatin
(Antifungal Agents) |
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What's the primary treatment for Nystatin?
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Topical, 10-14 days
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*clotrimazole
*miconazole *ketaconazole |
Types of Imidazoles
(Antifungal Agents) |
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synthetic antifungal agent, avaiable in creams, oinments, lozenges
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Imidazoles
(Antifungal Agents) |
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What do Imidazoles alter?
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Cell wall permeability
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What are the adverse reactions for Imidazoles?
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Mostly GI
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Which Imidazoles is contraindicated during pregnancy?
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Ketaconzole is contraindicated during pregnancy (oligodactly, syndactly, embryotoxicity)
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*Ususully used to treat serious systemic fungal diseases
*little dental uses (used to treat athletes foot) |
Amphotericin B And Griseofulvin
(Antifungal Agent) |
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Acyclovir (Zovirax)
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Antiviral Agents
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*inhibits DNA/RNA synthesis
*applied topically or systemically *distributed well in all tissues *selectively toxic to infected host cells |
Acycylovir (Zovirax)
(Antiviral Agent) |
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What are the adverse effects for Acyclovir (Zovirax)?
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Headache, burning, itching, GI
(used to treat fever blisters) |
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*used for prevention of bacterial endocarditis
*used when possibility of introducing significant bacteremias *based upon American Heart Association recommendations *also used in prostheic joint replacements *primary and speciality physicians should be consulted |
Antiboitic PreMedication
|
|
*Nystatin
*Imidazoles *Amphotericin B and Griseofulvin |
Antifungal Agents
|
|
Mycostatin, Lamisil, Nizoral
|
Nystatin
(Antifungal Agents) |
|
fungicidal and fungistatic antiboitic by altering cell wall permeability
|
Nystatin
(Antifungal Agents) |
|
*poorly aborsorbed through mucosa,skin, or GI
*few adverse effects |
Nystatin
(Antifungal Agents) |
|
What's the primary treatment for Nystatin?
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Topical, 10-14 days
|
|
*clotrimazole
*miconazole *ketaconazole |
Types of Imidazoles
(Antifungal Agents) |
|
synthetic antifungal agent, avaiable in creams, oinments, lozenges
|
Imidazoles
(Antifungal Agents) |
|
What do Imidazoles alter?
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Cell wall permeability
|
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What are the adverse reactions for Imidazoles?
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Mostly GI
|
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Which Imidazoles is contraindicated during pregnancy?
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Ketaconzole is contraindicated during pregnancy (oligodactly, syndactly, embryotoxicity)
|
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*Ususully used to treat serious systemic fungal diseases
*little dental uses (used to treat athletes foot) |
Amphotericin B And Griseofulvin
(Antifungal Agent) |
|
Acyclovir (Zovirax)
|
Antiviral Agents
|
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*inhibits DNA/RNA synthesis
*applied topically or systemically *distributed well in all tissues *selectively toxic to infected host cells |
Acycylovir (Zovirax)
(Antiviral Agent) |
|
What are the adverse effects for Acyclovir (Zovirax)?
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Headache, burning, itching, GI
(used to treat fever blisters) |
|
*Nucleoside
*Nonnucleoside *Protease |
Types of HIV agents
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Reverse transcriptase inhibitors
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*Nucleoside
*Nonnucleoside |
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Inhibitors
(hiv agents) |
Protease
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*All have variable side effects
*Frequently used in combinations |
HIV Agents
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What are the adverse effects for HIV Agents?
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may have GI, CNS, and bone marrow suppression
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