Pharmii - Inhaled Anesthetics

Front 1

What is the meyer - overton rule related to?

Back 1

Potency of volatiles. The more lipid soluble they are the more potent they are.

Front 2

Which volatile decreases the cerebral metabolic rate the most?

Back 2

Isoflurane

Front 3

What is the only anesthetic capable of producing an isoelectric EEG at a clinical dose?

Back 3

Isoflurane

Front 4

Which volatile increases CSF absorption?

Back 4

Isoflurane

Front 5

When is MAC highest according to age?

Back 5

Between 6-12 months

Front 6

What are four factors that decrease MAC?

Back 6

Hypoxia
Hypothermia
Acidosis
Hypercapnia

Front 7

Why does N2O itself produce an increase in SVR and PVR?

Back 7

It has sympathomimetic effects

Front 8

Rank the agents from causes PONV to may cause PONV

Back 8

N2O - Des - Iso - Sevo

Front 9

Which two agents most decrease SVR?

Back 9

Iso and Des

Front 10

How does Iso reduce temperature?

Back 10

Suppresses brain autoregulation of temp control and reduces shivering

Front 11

What volatile agent most decrease CMR?

Back 11

Iso - des - sevo all have similar effects.

Front 12

Which agent is least likely to cause increases in ICP if modest hypocapnia is present?

Back 12

Iso

Front 13

Which agent is most likely to cause coughing during LMA use?

Back 13

Iso

Front 14

Which volatile is completely halogenated with fluorine?

Back 14

Des

Front 15

Which volatile most suppresses ventilation?

Back 15

Des

Front 16

Which volatile least depresses ventilation

Back 16

Halo

Front 17

Which volatile most depresses the baroreceptor reflex?

Back 17

Sevo - Halo

Front 18

Which volatile least depresses baroreceptor reflex?

Back 18

Des - Iso

Front 19

Which agent is most degraded by soda lime? Least?

Back 19

Sevo - most
Des - least

Front 20

How are the volatiles carried in the blood?

Back 20

Dissolved

Front 21

MAC of an inhaled anesthetic is inversely related to what?

Back 21

Potency

Front 22

What electrolyte imbalances will cause MAC to increase? Decrease?

Back 22

Hypernatremia - increase
Hypercalcemia and Hyponatremia - decrease

Front 23

What three renal changes are associated with volatile administration?

Back 23

Decreased renal blood flow, glomerular filtration rate, and UOP.

Front 24

List the agents from most to least metabolized

Back 24

Halo 20 - Sevo 4 - Iso 0.2 - Des 0.02

Front 25

Are Iso, Sevo, and Des metabolized by Oxidation or Reduction?

Back 25

Oxidation

Front 26

What is the only agent without Halogen (Cl, Fl, Br)?

Back 26

N2O

Front 27

What is N2O's effect on the brain?

Back 27

Increase CMRO2 and increase ICP

Front 28

Which volatile is best for maintaining the autoregulation in the brain?

Back 28

Iso

Front 29

Which agent does not relax skeletal muscles?

Back 29

N2O

Front 30

Which agent has coronary steal?

Back 30

Iso

Front 31

Which agent is best for CV stability?

Back 31

Sevo

Front 32

Which agent is most pungent?

Back 32

Des

Front 33

Which agents are good bronchodilators?

Back 33

All of them

Front 34

Which agent is good for asthmatics and for mask inductions?

Back 34

Sevo

Front 35

Which agent is metabolized by the liver the most?

Back 35

Halo

Front 36

Which agents reduce renal blood flow?

Back 36

All of them

Front 37

Which agent causes dysrythmias and loss of baroreceptor function?

Back 37

Halothan

Front 38

Which agent must you limit your use of Epi?

Back 38

Halothan

Front 39

Which agent can cause seizures?

Back 39

Sevo

Front 40

Which agent can prolong the QT even 30 minutes after the case?

Back 40

Sevo

Front 41

Increased MAC requirements

Back 41

Drugs - amphetamines, cocaine, ephedrine, ethanol
Age - 1-6 months
Hypernatremia
Hyperthermia
Red hair

Front 42

Decreased MAC requirements

Back 42

Drugs - (all anesthetics) lithium, verapamil
Age - elderly
Hyponatremia, hypercalcemia
Anemia, hypercarbia, hypothermia, hypoxia, pregnancy

Front 43

Which agent increases PVR?

Back 43

N2O

Front 44

Which agent has simpathomimetic properties offsetting any myocardial depression?

Back 44

N2O

Front 45

Which agent has the greatest risk for Carbon Monoxide build up?

Back 45

Des

Front 46

Which p-450s enzymes metabolize agents?

Back 46

2E1

Front 47

Which agent blocks the baroreceptor response?

Back 47

Iso

Front 48

Which agent most increases CBF and ICP?

Back 48

Halo

Front 49

Which agent decreases BP by decreased contractility?

Back 49

Halo

Front 50

Which agent is the most likely to cause post op shivering?

Back 50

Halo

Front 51

Which agent is the bigger MH trigger?

Back 51

Halo