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52 Cards in this Set
- Front
- Back
- 3rd side (hint)
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rosuvastatin
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Crestor
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IIa, IIb, IV; 5-40 mg; inc. warfarin serum levels, gemfibrozil inc. crestor levels; antacids dec. absorb; not 2 h before or after meals
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fluvastatin
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Lescol/XL
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IIa, IIb; 20-80 mg QD, XL 80 mg QHS; less potent
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atorvastatin
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Lipitor
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IIa, IIb; 10-80 mg QD; CYP 3A4, may inc digoxin levels; azoles inc atorv levels; grapefruit juice inc atorv; very portent; take anytime
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lovastatin
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Mevacor
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IIa, IIb; 20-80 mg QPM; CYP 3A4; ci: itraconazole/sporanox; azoles/gf juice inc levels; take w/ evening meal
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pravastatin
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Pravachol
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IIa, IIb; 10-80 mg QHS; BAS dec absorb; give 1 hr before or 4 hr after BAS; take @ bedtime
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simvastatin
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Zocor
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IIa, IIb, IV; 5-80 mg QPM; CYP 3A4; no 80 mg in new pats; ci; sporanox; most hepatotoxic; may inc dig & warfarin; evening dosing; c. sporine A; amiodarone, verapamil, azole, gf juice, protease i., nefazadone inc sim
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gemfibrozil
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Lopid
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IV; 600 mg BID; 30 min before meals; may inc warfarin levels; w/ statin leads to myopathy, ci: liver dx, renal dx, gb dx
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fenofibrate
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Tricor, Trilipix
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IIa, IIb, IV; 48-145 mg QD; take w/ food; interacts w/ warfarin & statins; ci: liver dx, renal dx, LPT inc, GB dx; micronized vs non-micronized
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omega 3 acid ethyl esters
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Lovaza
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Hyper TG > 500; 4 caps QD or 2 caps BID; inc bid time w/ warfarin; caution fish allergy; take w/ food; AE: belching, dyspnea, taste change; take w/ food, contains DHA
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cholestyramine
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Questran
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IIa; 4-16 g/d; can divide prn, max 24 g; mix w/ cold h2o; dec absorb of many drugs; caution gi motility; give other meds 1 hr before or 4 hr after
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colesevelam
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Welchol
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IIa; 6 t QD or 3 t BID; take w/ meals; caution GI motility; AE: constipation, dyspepsia, ample fluids
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niacin
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Niaspan
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IIa, IIb, IV; 500 - 2000 mg QHS w/ snack; inc statin leads to myopathy; titrate; no EtOH; ci: liver dx, inc LFT, DM, gout; AE: flushing, pruritus, rash, GI
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ezetimibe
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Zetia
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IIa; 10 mg QD; mono or combo w/ statin; myopathy; fib acids inc zet levels; cholesyt dec zet levels; AE: minimal; caution liver dx
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ezetimibe/simvastatin
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Vytorin
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hyperlipidemia; 10/10 - 10/80 mg QD; Zocor & Zetia info
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furosemide
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Lasix
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CHF; 20-160 mg; max rqd bid dosing; tab, soln, iv; oral > 300 mg may be needed, oral bioavail 50-60%; loop; onset 30-60 min, pk 1 h (oral)
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bumetanide
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Bumex
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CHF; 0.5-4 mg QD; oral, IV; loop; max 10 mg QD; onset 30-60 min; pk 1 h; F=80-90%; no IV adjustment
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torsemide
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Demadex
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CHF: 20-200 mg QD; HTN: 10-200 mg QD; oral & IV
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HCTZ
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HCTZ
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HTN; 12.5-50 mg QD; t; caution: impaired renal fx dec effectiveness; need GFR > 30 ml/min
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indapamide
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Lozol
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CHF: 2.5-5 mg QD; HTN: 1.25-2.5 mg QD; t
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metolazone
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Zaroxolyn
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CHF/renal dysfx; 2.5-20 mg QD; t; may use in combo w/ loop; give metaz 30 min before to inc diuresis; check F/E
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spironolactone
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Aldactone
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edema: 25-200 mg QD; HTN: 50-100 mg QD; used in nephrotic syndrome; interact: ace, K spar, K supp; ci: anuria/renal insuff, hyper K; AE: hyper K, boobies
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eplerenone
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Inspra
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CHF post MI, HTN; 50 mg QD; titrate to 50 mg BID after 4 wks prn; CYP 3A4; ci: K>5.5, CrCl < 30; CYP inhib clarithro; AE: dz, HTN & complication DM; inc CrCl<50, use K
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Triamterene/HCTZ
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Dyazide
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edema, HTN; 1-2 caps QD; 37.5/25 mg cap; caution w/ other K sparing agents
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Triamterene/HCTZ
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Maxzide
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edema, HTN; 1 t QD; 37.5/25mg, 75/50 mg; caution w/ other K sparing agents
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potassium chloride
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N/A
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supplement; 16-80 mEq/day; can div to dec GI upset; take w/ meal & full glass h2o; tab, powder, cap, liq, IV; K-shell in stool
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clopidogrel
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Plavix
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dec risk of CV events; 75 mg QD; report unusual bleeding; prodrug; irrev effect of plt; interact w/ phenytoin; AE: HA, dzy, arthralgia
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ticlodipine
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Ticlid
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dec CVA; 250 mg BID; take w/ meals; irrev effect of plt; ci: blood dyscrasias; AE: neutropenia, thrombocytopenia, monitor CBC
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prasugrel
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Effient
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dec risk of CV events; 10 mg QD; irrev effect on plt; inc risk of bleed w/ warfarin; AE: HA, dzy, bleed; ci: after CVA/TIA; avoid > 75 y.o., inc bleed risk <60 kg
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dipyridamole
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Persantine
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thrombotic event risk, dec w/ warfarin post valve replacement; 100 mg qid; often coadmin w/ warfarin/ASA; AE: drowsy, dzy, hypoTN in elderly
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dipyridamole/ASA
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Aggrenox
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CVA prevention w/ h/o TIA/CVA; 200/25 mg cap div BID; secondary prevention; Persantine & ASA info
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pentoxifylline
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Trental
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intermittent claudication; 400 mg TID; take w/ meals; can dec to BID if GI SE; inc theophylline levels; AE: drowsy, GI; effect in 2-4 wks, full in 8-12 wks
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cilostazol
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Pletal
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intermittent claudication; 100 mb bid; take 30 min before or 2 h after meal; ci: CHF; 2 wks for effect, fill in 12 wks; CYP 3A4, dose adj for interaction: diltiazem, GF juice, plt drgs
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warfarin
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Coumadin
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Afib, CVA prevent, VTE, other; 1-10 mg; CYP 3A4, 2C9; AE: bruise/bld; ci: preg; pep ulcer; hem tend; no EtOH, ASA, consist Vit K
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dabigatran
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Pradaxa
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Afib, CVA prevent; 150 mg BID; VTE; inhib fibrinogen to fibrin; direct thrombin inhib; free & clot bound, inhib plt aggreg; less monitoring than warfarin
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terasozin
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Hytrin
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HTN; 1-5 mg QD; start low; 1st dose @ bedtime; orthostatic counseling
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doxasozin
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Cardura/XL
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HTN/BPH (IR) 1-16 mg QD & BPH (SR) 4 mg QD; start low, 1st dose @ bedtime; pk 2-3 h; can inc to 8 mg QD in 4 wks take in AM w/ meal, shell in stool
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prazosin
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Minipress
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HTN; 2-5 mg TID; start low; 1st dose @ bedtime; orthostatic counseling
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hydralizine
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Apresoline
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HTN; 10-50 mg QID; +/- nitrate in CHF; caution: long term leads to lupus; AE: dzy, edema; w/ isorbide in CHF; take w/ food report fatigue, aches
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clonidine
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Catapress/TTS
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HTN; 0.1-0.4 mg BID tab; 0.1 g patch q 7 days; interact w/ BB; AE: sedation; don't DC abruptly-rebound HTN; apply to hairless healthy skin
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nifedipine
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Procardia/XL
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vasospastic+chronic stable angina, XL-HTN; 30-120 mg QD div doses-not optimal dosage, V-30-180 mg QD empty stomach; H-30-90 mg QD empty stomach interact w/ GF & cimitedine
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felodipine
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Plendil
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HTN; 2.5-20 mg QD; AE: rare gingivial hyperplasia; counsel dental hygiene
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amlodipine
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Norvasc
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HTN-2.5-10 mg QD, vasosp/CSA-10 mg QD; long tyz
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amlodipine/benazepril
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Lotrel
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HTN; 2.5/10, 5/10, 5/20, 5/40, 10/20, 10/40; div cap QD; DHP & ACE
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diltiazem
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Cardizem CD/SR, Dilacor XR
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angina proph 30 mg QID before meals & @ HS, HTN 120 -360 mg QD or 120 -540 QD empty stomach; oral & IV
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verapamil
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Isoptin/SR
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vasosp/CSA 80-160 mg TID (usual 240-480 mg QD), 120-240 mg QD-BID; ci: sever lv dysfx; AE: constipation
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isosorbide dinitrate
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Isosorbide Dinitrate/SR
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angina 40 mg TID - dose @ 7, 12, 5; proph 40 mg BID dose @ 8,2; ci w/ Viagra; AE: HA, dzy, flush, nausea; long term tolerance
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isosorbide mononitrate
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Imdur
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angina, proph; 30-240 mg QD; scored tab; can split, don't crush
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nitroglycerin
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Nitrostat
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acute angina pain; q 5 min prn; 3 tab/15 min than call 911; prn sit down; AE: reflex tachycardia; sit down dissolve under tongue; good for 6 months
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transdermal NTG
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Nitro-Dur
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prevent & tx angina; apply 1 patch QAM, remove after 12 h; don't wear > 4 h; apply to chest, back rotate site daily
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digoxin
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Lanoxin tab
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CHF, Afib, Aflut; 0.125-0.25 mg QD; dose adjust in renal dx; interact w/ diuretic, amiodarone, erythromycin, AE: anorexia, same time QD, blur vision, HA; toxic-green halo
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amiodarone
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Pacerone, Cordarone
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A/V, arrhythmias; 200-400 mg QD (maint dose); LD common, wks to respond; t1/2-50 d; interact w/ dig, warfarin, inc INR; ci: sinus node dysfx, resp/hep tox
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dronedarone
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Multaq
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Afib, Aflutter; 400 mg BID; w/ meals; AE: N/V/D; ci: HF; fewer AE than amiodarone; monitor LFT
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