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29 Cards in this Set
- Front
- Back
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1. What is the use of ACE inhibitors to tx HF?
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a. DOC
b. HTN DOC |
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2. What is the MOA of ACE inhibitors?
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a. Inhibit conversion of Ang I to Ang II
b. Decrease afterload and preload c. Prevent ventricular remodeling |
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3. What are the adverse effects of ACE inhibitors?
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a. Cough due to increased bradykinin
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4. What are the contraindications of ACE inhibitors?
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a. Pregnancy
b. Bilateral renal arterys tenosis |
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5. What is the use of ARBs to tx HF?
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a. CHF 2nd line
b. HTN |
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6. What is the MOA of ARBs?
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a. Block At1 receptor in blood vessels and heart
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7. What are the contraindications of ARBs?
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a. Pregnancy
b. Bilateral renal artery stenosis |
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8. What are the K sparing diuretics?
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a. Aldosterone receptor antagonists
b. Spironolactone c. Eplerenone |
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9. What is the clinical use of K sparing diuretics?
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a. CHF
b. Cirrhosis DOC |
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10. What is the MOA of K sparing diuretics?
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a. Aldosterone receptor antagonist in collecting tubule
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11. What are the contraindications of K sparing diuretics?
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a. Oral K administration
b. Hyperkalemia c. Renal insufficiency |
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12. What is the clinical use of carvedilol?
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a. CHF DOC
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13. What is the MOA of carvedilol in the tx of CHF?
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a. Blocks a1, B1, and B2 receptors
b. Antioxidant and antiproliferative effects |
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14. What are the contraindications for carvedilol?
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a. Asthma/COPD
b. Diabetes |
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15. What is the clinical use of metoprolol in the tx of CHF?
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a. CHF DOC
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16. What is the MOA of metoprolol?
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a. B1 blocker
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17. What class of drug is furosemide?
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a. Sulfonamide loop diuretic
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18. What is the clnical use of furosemide?
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a. Edematous states DOC
b. Severe CHF |
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19. What is the MOA of furosemide?
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a. Inhibits Na/K/Cl transporter in thick ascending loop
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20. What is the clinical use of digoxin in the tx of CHF?
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a. CHF patients in a-fib
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21. What is the MOA of digoxin?
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a. Inhibits Na/K ATPase
b. Positive inotropic state |
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22. What will a therapeutic dose of digoxin lead to?
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a. Stimulation of parasympathetic
b. Long PR interval |
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23. What will a high dose of digoxin lead to?
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a. Sympathetic stimulation
b. AV block |
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24. What is hydralazine?
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a. Arteriolar dilator
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25. What are isosorbide dinitrates?
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a. Venodilators
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26. What is the clinical use of hydralazine+isosorbide dinatrates?
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a. CHF ssx
b. For pts intolerant to ACE and ARB |
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27. What is the MOA of hydralazine+isosorbide?
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a. Decrease preload and afterload
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28. What are the chronic oral tx for chf?
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a. Glycosides
b. B blockers c. RAAS inhibitors d. Diuretics |
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29. What are the acute IV tx for CHF?
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a. Sympathomimetics
b. Vasodilators c. Diuretics (loop) |
