Pharmacotherapy - Anticoagulation

Front 1

A venous thromboembolism (VTE) manifests as which of the following?
I. DVT
II. PE
III. CVA

a. I only
b. III only
c. I and II only
d. II and III only
e. I, II, and III

Back 1

c. I and II only

Front 2

Which of the following are considered risk factors for a VTE?
a. Cancer
b. Obesity
c. Knee replacement
d. All of the above

Back 2

d. All of the above

Front 3

Which of the following most correctly describes the sequence of events in clot formation?
a. Platelet adhesion, coagulation cascade, fibrin formation
b. Coagulation cascade, platelet adhesion, fibrin formation
c. Fibrin formation, platelet adhesion, coagulation cascade
d. Platelet adhesion, fibrin formation, coagulation cascade
e. Coagulation cascade, fibrin formation, platelet adhesion

Back 3

a. Platelet adhesion, coagulation cascade, fibrin formation

Front 4

True (A) or False (B) A deep vein thrombosis and/or pulmonary embolus can be asymptomatic.

Back 4

True

Front 5

Which anticoagulant requires frequent lab monitoring?
I. LMWH
II. Warfarin
III. UFH

a. I only
b. III only
c. I and II only
d. II and III only
e. I, II, and III

Back 5

d. II and III only

Front 6

Which of the following is NOT considered a sign/symptom of bleeding?
a. nose bleed
b. unexpected bruises
c. blood in stool
d. hunger
e. headaches

Back 6

d. hunger

Front 7

Which of the following is least likely to occur during therapy with an anticoagulant?
a. formation of fibrin
b. osteoporosis
c. skin necrosis
d. thrombocytopenia

Back 7

a. formation of fibrin

Front 8

Which one of the following is the best clinical description of a bleeding disorder:
a. swelling in legs
b. angina (severe, sharp chest pain)
c. black, tarry stools
d. superficial thrombophlebitis (pain, redness in veins)

Back 8

c. black, tarry stools

Front 9

All of the following are major components necessary for regulating the normal hemostatic
system EXCEPT:
a. coagulation system
b. white blood cells
c. endothelial vessel wall
d. fibrinolytic system
e. platelets

Back 9

b. white blood cells

Front 10

Which one of the following the most likely side effect associated with the use of
anticoagulants?
a. tachycardia (heart rate > 100 beats/minute)
b. nasal congestion
c. diaphoresis (excessive sweating)
d. bradycardia (heart rate < 60 beats/minute)
e. hemiplegia (one-sided paralysis)

Back 10

a. tachycardia (heart rate > 100 beats/minute)

Front 11

Major causes of a bleeding disorder include all of the following EXCEPT:
a. vitamin K deficiency
b. liver disease
c. thrombosis
d. impaired platelet function
e. vascular malformations

Back 11

c. thrombosis

Front 12

Which one of the following is a potentially serious, life-threatening side effect of fibrinolytic
therapy that requires IMMEDIATE medical attention:
a. hemorrhage
b. anaphylaxis
c. epistaxis (nosebleed)
d. diaphoresis

Back 12

b. anaphylaxis

Front 13

Available pharmacotherapeutic options for managing clotting disorders include all of the
following EXCEPT:
a. vitamin K supplementation
b. antiplatelets
c. clot dissolvers
d. anticoagulants
e. fibrinolytics

Back 13

a. vitamin K supplementation

Front 14

Pertinent counseling points for patients on antiplatelet therapy include all of the following
EXCEPT:
a. avoid alcohol
b. discontinue use 5 days prior to elective surgery
c. monitor closely for signs of bleeding
d. protect from light

Back 14

d. protect from light

Front 15

Which one of the following is the best description of a sign/symptom of a clotting disorder?
a. hemarthrosis (bleeding into joint)
b. hematuria (blood in urine)
c. intracranial hemorrhage
d. recurrent epistaxis
e. angina

Back 15

e. angina

Front 16

A 35 year old woman is found to have renal artery thrombus and her physician wishes to treat this
problem aggressively. Use of which of the following will most likely result with immediate dissolution of this clot?
a. use of a glycoprotein IIb/IIIa inhibitor
b. use of a thrombolytic agent
c. use of unfractionated heparin, an anticoagulant
d. use of warfarin, an anticoagulant

Back 16

b. use of a thrombolytic agent

Front 17

A 35 year old woman is found to have renal artery thrombus and her physician wishes to treat this
problem aggressively. She eventually receives lovenox (Enoxaparin), an anticoagulant,
and aspirin, an anti-platelet agent. Monitoring of which of the following would be LEAST useful for
assessment of efficacy and/or safety?
a. signs and/or symptoms of the clot
b. vital signs (i.e. BP, HR, RR, temp)
c. platelet count
d. coagulation test

Back 17

d. coagulation test

Front 18

Atherosclerosis
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 18

b. Enthothelial Injury

Front 19

Paralysis
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 19

c. Circulatory Stasis

Front 20

Surgery
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 20

c. Circulatory Stasis

Front 21

Hip/Knee Replacement
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 21

b. Enthothelial Injury

Front 22

Estrogen Therapy
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 22

a. Hypercoagulate State

Front 23

Valvular Disease or Replacement
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 23

b. Enthothelial Injury

Front 24

Increasing Age
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 24

c. Circulatory Stasis

Front 25

Protein C and S Deficiency
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 25

a. Hypercoagulate State

Front 26

Malignancy
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 26

a. Hypercoagulate State

Front 27

Pregnancy
a. Hypercoagulate State
b. Enthothelial Injury
c. Circulatory Stasis

Back 27

a. Hypercoagulate State

Front 28

Varicose Veins
a. Hypercoagulate State
b. Endothelial Injury
c. Circulatory Stasis

Back 28

c. Circulatory Stasis

Front 29

Trauma
a. Hypercoagulate State
b. Endothelial Injury
c. Circulatory Stasis

Back 29

b. Endothelial Injury

Front 30

Indwelling venous catheters
a. Hypercoagulate State
b. Endothelial Injury
c. Circulatory Stasis

Back 30

b. Endothelial Injury

Front 31

Obesity
a. Hypercoagulate State
b. Endothelial Injury
c. Circulatory Stasis

Back 31

c. Circulatory Stasis

Front 32

Medical Illness
a. Hypercoagulate State
b. Endothelial Injury
c. Circulatory Stasis

Back 32

c. Circulatory Stasis

Front 33

Previous DVT/PE
a. Hypercoagulate State
b. Endothelial Injury
c. Circulatory Stasis

Back 33

b. Endothelial Injury