Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
25 Cards in this Set
- Front
- Back
|
anesthetic potency is related to ___
|
lipid solubility
|
|
|
inhaled anesthetics act by ___ing which causes ___ in ___
|
being absorbed into plasma membrane
conformation changes membrane proteins |
|
|
T/F: all inhalation anesthetics decrease activity in the reticular system
|
false
|
|
|
in patch clamp preparations, ACh channels ___ after isoflurane administration
|
open for shorter durations
|
|
|
___ is the best estimate of anesthetic potency
this means ___. |
minimal alveolar concentration (MAC)
minimal concentration causing immobility in response to noxious stimulus in 50% of patients |
|
|
MAC awake means
|
lack of response to verbal command
|
|
|
MAC intubation is greater/less than MAC awake
|
greater
|
|
|
as body temp goes down, MAC goes up/down
|
down
|
|
|
as hydrostatic pressure increases MAC goes up/down
|
up
|
|
|
MAC is highest in baby/old dude
|
baby
|
|
|
MAC goes up with increasing ___emia but doesn't change with ___emia (2)
|
hypernatremia
hyperkalemia hypermagnesemia |
|
|
decerebration increases/decreases MAC
|
doesn't affect
|
|
|
T/F: giving 0.5 MAC of 2 different anesthetics should produce 1 MAC effect
|
true
|
|
|
isoflurane is more potent than ___, even though the 2 are ___. this is an exception to ___.
|
enflurane
isomers Meyer-Overton rule |
|
|
the rate at which the alveolar anesthetic concentration (F_A) rises to the inspired concentration (F_i) is determined by ___ (2)
|
F_i
alveolar ventilation |
|
|
equation for uptake in terms of lipid solubility (lambda), CO (Q), and delta P between alveoli and pulmonary vein
|
uptake = (lambda x Q x delta P)/(barometric pressure)
|
|
|
___ is required to achieve 1 MAC with N2O. this means MAC is a ___ anesthetic
|
hyperbaric N2O
incomplete |
|
|
N2O has ___ onset and recovery
it is used for ___ with ___. it can cause ___ |
fast
induction other anesthetics megaloblastic anemia |
|
|
halothane can cause ___ (3)
|
arrhythmia
hepatitis malignant hyperthermia |
|
|
___ was the most common inhalation anesthetic but was replaced by desflurane. it has ___ onset and recovery
|
isoflurane
medium |
|
|
risk for malignant hyperthermia is highest when inhaled anesthetics are used with ___
immediate tx with ___ is required |
succinylcholine
dantrolene |
|
|
halothane is metabolized by ___
|
liver
|
|
|
low blood/gas partition coefficient means
2 anesthetics with low partition coeffs |
high lipid solubility
desflurane sevoflurane |
|
|
N2O can cause ___ anemia by downregulating ___, causing ___.
|
megaloblastic
Met synthetase B12 deficiency |
|
|
___ doesn't cause malignant hyperthermia
|
propofol
|
