Pharmacology Week One

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PHARMACODYNAMICS

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STUDY OF THE MECHANISMS OF ACTION OF DRUGS WITHIN THE BODY & HOW DRUGS PRODUCE THEIR EFFECTS IN THE BODY.

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PHARMACOGENETICS

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STUDY OF DRUG REACTIONS IN THE BODY THAT ARE UNANTICIPATED OR UNUSUAL,& MAY HAVE A HEREDITARY BASIS FOR RESPONSE

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PHARMACOKINETICS

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STUDY OF DRUG ACTIONS AS THEY OMVE THROUGH THE BODY;THE WAY BODY ABSORBS, DISTRIBUTES, METABOLIZES AND EXCRETES DRUGS, MATHEMATICAL STUDY OF DRUGS BASED ON TIME AND DOSE

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PHARMACOLOGY

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STUDY OF HOW BIOLOGICALLY ACTIVE COMPOUNDS, HOW THEY REACT IN THE BODY AND HOW THE BODY REACTS TO THEM

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PHARMACOTHERAPUETICS

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STUDY OF DRUGS USED TO PREVENT, TREAT, OR DIAGNOSE DISEASE

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PHARMACY

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PREPARATION AND DISPENSING OF DRUGS

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TOXICOLOGY

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STUDY OF HARMFUL OR POISIONOUS EFFECTS OF DRUGS

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DRUG'S CHEMICAL NAME

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SCIENTIFIC NAME, DESCRIBES ATOMIC AND MOLECULAR STRUCTURE OF A DRUG

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DRUG'S GENERIC NAME

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NONPROPRIETARY NAME, ABBRIEVIATION OF CHEMICAL NAME

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DRUG'S TRADE NAME

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BRAND NAME, TRADE NAME, SELECTED BY THE PHARMACEUTICAL COMPANY THAT MADE THE DRUG

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RECEPTORS

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PROTIEN MOLECULES W/ ONE OR MORE BINDING SITES, LOCATED ON CELL MEMBRANES. RECIEVE SIGNALS FROM BODYS CHEMICALS (NEUROTRANSMITTERS, HORMONES, ENZYMES)

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AFFINITY

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ATTRACTION BETWEEN A DRUG AND A RECEPTOR

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HIGH AFFINITY

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DRUG WILL BIND EASILY TO THE RECEPTOR

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LOW AFFINITY

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REQUIRES A HIGHER CONCENTRATION OF THE DRUG TO GET A THERAPUETIC RESPONSE

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DRUG POTENCY

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AMOUNT OF A DRUG REQUIRED TO PRODUCE A THERAPUETIC RESPONSE

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EFFECTIVE DOSE
(ED)

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AMOUNT OF DRUG THAT PRODUCES A THERAPEUTIC RESPONSE IN 50% OF THE PPL TAKING IT

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ENTERAL ROUTE

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ENTERS THE BODY THROUGH THE GI TRACT. TAKEN BY MOUTH, THROUGH THE RECTUM, UNDER THE TONGUE OR HELD IN THE CHEEKS (BUCCAL)

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PARENTERAL

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ENTERS THE BODY THRU MEANS OTHER THAN THE GI TRACT-
CAN BE INJECTED THRU VIENS, ARTERIES, MUSCLES, SPINAL CORD, UNDER SKIN, INHALED THRU LUNGS,TRANSDERMALLY THRU SKIN BY PATCH OR OINTMENT

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TISSUE PERMEABILITY

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ABILITY OF A DRUG TO PASS THROUGH THE MEMBRANES RAPIDLY AFFECTS THE EXTENT TO WHICH THE DRUG MOVES AROUND THE BODY

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HALF LIFE

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TIME REQUIRED TO DECREASE THE BLOOD LEVELS OF A DRUG BY ONE HALF,

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STEADY STATE

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RATE OF DRUG ADMINISTRATION IS EQUAL TO THE RATE OF DRUG EXCRETION

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ORGANS THAT EXCRETE DRUGS

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KIDNEYS, LUNG, SWEAT GLANDS, MAMMARY GLANDS, SALIVARY GLANDS, SKIN AND GI TRACT

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SCHEDULE 1 DRUGS (C-I)
HIGH ABUSE POTENTIAL/NOTLEGAL/NO ACCEPTABLE MEDICAL USE/NO RX AVAIL.

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EX: HEROIN, LSD,COCAINE, MARIJUANA, METHAQUALONE

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SCHEDULE 2 DRUGS (C-II)
HIGH ABUSE POTENTIAL,SEVERE DEPENDANCE LIABILITY, CURRENT ACCEPTABLE MEDICAL USE, RX DRUG-SIGNED, NON-STAMPED RX, 30 DAY SUPPLY, NO REFILLS

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EX:OPIUM, MORPHINE, COCA,METHADONE

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SCHEDULE 3 DRUGS (C-III)
LESS ABUSE POTENTIAL,LOW-MODERATE PHYSICAL DEPENDANCE, HIGH PSYCHLOGICAL DEPENDANCE, BY RX ONLY, EXP. W/I 6 MO., MAX 5 REFILL ON 1 SCRIPT

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EX:AMPETAMINES, CODIENE, BARBITUATES, VALIUM, XANAX, ANABOLIC STERIODS

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SCHEDULE4 DRUGS (C-IV)
LESS ABUSE POTENTIAL THAN C-III DRUGS, ACCEPTED MEDICAL USE, LIMITED PHYSICAL+PSYCHOLOGICAL DEPENDANCE, WRITTEN OR VERBAL RX, EXP. IN 6 MO., MAX. 5 REFILLS ON 1 SCRIPT

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EX:CHLORAL HYDRATE, MEPTROBAMATE, PARALDEHYDE, PHENOBARBITAL

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SCHEDULE 5 DRUGS (C-V)

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LIMITED ABUSE POTENTIAL, ACCEPTED MEDICAL USE, SMALL AMTS OF NARCOTICSUSED AS ANTITUSSIVES (COUGH MED) OR ANTIDIARHEALS,MAY NOT NEED AN RX BUT MAST BE RECORDED AS A TRANSACTION.