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9 Cards in this Set

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This is one of the most important risk factors for the developmemt of CHD.
How is cholesterol used in the body?
- structure of cell membrane
- synthesis of certain hormones (testosterone, estrogen, progesterone, adrenal corticosteriods - glucocorticoids,mineralcorticoids )
- synthesis of bile salts - components of bile
- synthesis of
What is an important enzyme for synthesis of cholesterol?
HMG - coenzyme A reductase

hydroxy- methyl glutaryl
high cholesterol aka

hypercholesterolemia = elevated SERUM levels of cholesterol
primary vs secondary hypercholesterolemia
primary - genetic

secondary - diet, disease, medication
What are secondary factors for development of dyslipidemia?
diet - intake of sat fats

disease - DM, obesity, obstructive liver disease?, alcoholism, hypothyroidism

Medications - beta-blockers, thiazide diuretics, cyclosporins, ..oral estrogens, glucocorticoids
Would ingesting cholesterol or saturated fats increase serum cholesterol?
ingesting cholesterol increases it a little, but there is a compensatory mechanism in which the body limits cholesterol production

ingesting sat. fats increases chol levels much more
What is normal levels for serum triglycerides?
At what levels should you maintain your cholesterol? LDL and HDL?

what is considered high?
total cholesterol should stay < 200mg/dl. High > 240.

LDL stay < 100. High >160.

HDL is better if higher. <40 is low.