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20 Cards in this Set
- Front
- Back
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how do prostaglandins work?
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reduce stomach acidity by affecting proton pump
milder acting than proton pump inhibitors useful for NSAID induced ulcerations |
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name an common prostaglandin.
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cytotec
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name three side effects of prostaglandins.
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nausea
diarrhea can cause uterine contractions in pregnancy |
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how do anti muscarinics work?
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block normal functioning of cholinergic receptors that activate proton pump
they decrease GI motility and gastric secretions |
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name the two major side effects of anti muscarinics.
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arrhythmias
urinary retention |
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what is sucralfate?
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enhances mucosal layer
adheres to damaged ulcer tissue protects against acid and enzymes stimulates prostaglandin secretion |
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what is an antimicrobial agent that can eradicate H. pylori?
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bismuth
antimicrobial and forms protective mucosal lining |
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what are some drug interactions that can occur with cimetidine?
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inhibits P450 and can slow metabolism of warfarin, diazepam, phenytoin, quinidine
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what are drug/herb side effects with omeprazole?
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interferes with oxidation of warfarin, phenytoin, and diazepam
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what are drugs interaactions with sucralfate? (IMPORTANT)
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it needs an acidic environment so should not be combined with histamine antagonists or antacids.
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name three herbs that reduce stomach acidity.
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hai paio xiao
wu zhu yu huang lian |
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what are the three main types of anti diarrheals?
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antimotility agents
adsorbents agents that modify fluid and electrolyte transport |
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what are antimotility agents?
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decrease peristalsis and slow the action of the intestines by activating presynaptic opioid receptors in the enteric nervous system
inhibits acetylcholine release |
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what are adsorbents?
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absorb intestinal toxins or microorganisms by protecting or coating the mucosa
provides bulk as a laxative |
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how do agents that modify fluid and electrolyte transport work?
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they inhibit prostaglandin synthesis (pepto bismol)
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what are the c/cs with adsorbents?
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the interfere with the absorption of other drugs.
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what are the c/cs with antidiarrheals?
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because they interfere with intestinal function, herbs should be given four hours before or after to ensure absorption.
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what are the 3 types of laxatives?
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irritants/stimulants
bulking agents stool softeners |
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how do bulking agents work?
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fiber causes intestines to distend thus causing peristalsis
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what are two side effects of laxatives?
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electrolyte imbalance
habituation |
