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10 Cards in this Set
- Front
- Back
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Cyclophosphamide
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Alkylating agent
USE: Non-hodkin, ovarian, breast, neuroblastoma ADVERSE: BMS+ hemorrhagic cystitis |
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Cisplatin
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Alkylating agent- cross links DNA
USE: testicular, ovarian, bladder, lung cancer ADVERSE: Nephro and Neurotoxic |
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Procarbazine
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Alkylating Agent
USE: Hodkins ADVERSE: BMS |
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Doxorubicin
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Forms free rads, inhibs topoisomerase
USE: Hodkins, breast, endometrial, lung, and ovarian ADVERSE: BMS, delayed CHF --can use dexrazoxane to prevent the formation of free rads |
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Methotrexate (CCS)
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Pyrimidine antimetabolite (s phase)
USE: Leukemias, lymphomas, breast, rheumatoid arthritis, psoriasis ADVERSE: BMS --can use leucovorin for rescue |
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5-Fluorouracil (CCS)
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Pyrimadine antimetabolite (s phase)
USE: brease, ovarian, head and neck,--topical for basal cell cancer ADVERSE: BMS |
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6-Mercaptopurine (CCS)
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Purine Antimetabolite
USE: Acute Lymphocytic Leukemia ADVERSE: BMS |
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Bleomycin (CCS)
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Complexes with Fe and O2 (G2 phase)
USE: Hodkins, testicular, head and neck, skin ADVERSE: Pneumonitis, pulmonary fibrosis |
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Vinblastine (CCS)
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Decreases microtubular polymerization (M phase)
USE: Hodkins, testicular, Kaposi ADVERSE: BMS |
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Vincristine
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Decreases microtubular polymerization (M phase)
USE: Hodkins, leukemias, Wilms ADVERSE: Neurotoxic |
