• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/27

Click to flip

27 Cards in this Set

  • Front
  • Back
Influences bulk, softness and hydration of stool
fiber
food contents that are resistant to enzymatic digestion
fiber
increases stool weight
bran
more than 40% fiber and left over flour production
bran
osmotically active agents
saline laxatives
cause water retention via osmotic mechanisms which increases peristalsis
saline laxatives
contain magnesium or PO4 ions
saline laxatives
nondigestible sugars/alcohols
lactulose/sorbitol/mannitol
short chain fatty acids
lactulose/sorbitol/mannitol
stimulate colonic motility by drawing water into the lumen by osmosis
**opioid induced constipation
lactulose/sorbitol/mannitol
wetting agent/emollients
docusate salts
anionic surfactants
docusate salts
lowers stool surface tension
docusate salts
AEs= interference with absorption of vitamins, foreign body reactions and leakage of oils (mineral oil)
docusate salts
direct actions on enterocytes, enteric neurons and GI smooth muscle (inflammation of bowel)
**BISACODYL
stimulant/irritant laxatives
activation of prostaglandins, NO, platelet activating factor production, inhibition of proton pump
stimulant/irritant laxatives
plant derivatives and contain monoanthrones which are converted to dianthrones and glycosides (stimulant/irritant laxatives)
anthraquinone laxatives
stimulant/irritant laxatives: anthraquinone laxatives
process of converting monoanthrones to dianthrones is revered by
colon bacteria to generate active agents
AEs=melanotic pigmentation and cathartic colon (nerve damage)
anthraquinone laxatives of stimulant laxatives
Contains ricin and triglyceride ricinoleic acid which is hydrolyzed into glycerin in small bowel
castor oil stimulant laxatives
bowel distension and evacuation reflex
**glycerin is an alcohol that is a hygroscopic agent and lubricant
enemas and suppositories
stimulate absorption and inhibit fluid/electrolyte secretion
alpha-2 adrenergic receptor agonists
clonidine
alpha-2 adrenergic receptor agonists
inhibits hormone secretion
*SST analogue
Octreotide
Verapamil/Nifedipine
calcium channel blockers
reduce motility and promote electrolyte and water absorption
calcium channel blockers
plant alkaloid which also reduces motility and promotes electrolyte/water absorption
berberine