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14 Cards in this Set

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Brand names for theophylline are?

(must have prescription)
Bronkodyl
Elixophyllin
So-Bid
Theo-Dur
Quibron-T
Uniphyl
Two classes of bronchodilators are?
xanthine derivatives and
beta-agonists
The net drug effect of all bronchodilators (beta-agonists, anticholinergics, xanthine derivatives, indirect-acting antiasthmatics, and corticosteroids) is
relaxation of bronchial smooth muscle
Theophylline is one of the most commonly used of all?
xanthine derivatives as well as of all bronchodilators
Theophylline is most frequently used in the treatment of?
chronic respiratory disorders
asthma
Theophylline may also be used for the relief of?
mild to moderate acute asthmatic attacks.
Avoid if hypersensitivity to?
xanthines
Avoid if patient has?
tacharrhythmias
Common therapeutic range in blood is?
10 to 20 micrograms/ml...levels ABOVE THIS ARE TOXIC AND FATAL!
Toxicity of xanthine derivatives in elderly...what are symptoms?
restlessness
insomnia
irritability
tremors
nausea
vomiting
restlessness due to possible
hypoxia
Encourage elderly not to ______ dose?
double...never omit doses...contact doctor if this occurs
Xanthines work by?
inhibiting phosphodiesterase...phosphodiesterase breaks down cAMP, which is needed to relax smooth muscle
Theophylline is the most common; what is the parenteral form of theophylline?
aminophylline
Xanthine derivatives are contraindicated in patients with a history of?
GI tract disorders or peptic ulcer disease